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UniProtKB - A0A2K5ZBS6 (A0A2K5ZBS6_MANLE)

Entry version 18 (10 Feb 2021)
Sequence version 1 (28 Mar 2018)
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Protein

Tower domain-containing protein

Gene

BRCA2

Organism
Mandrillus leucophaeus (Drill) (Papio leucophaeus)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingARBA annotation
Biological processDNA damage, DNA recombinationARBA annotation, DNA repairARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tower domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BRCA2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMandrillus leucophaeus (Drill) (Papio leucophaeus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9568 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Mandrillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000233140 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1007 – 1041BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1216 – 1250BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1424 – 1458BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1520 – 1554BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1667 – 1701BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1840 – 1874BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1974 – 2008BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati2055 – 2089BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati2228 – 2262BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati2309 – 2343BRCA2PROSITE-ProRule annotationAdd BLAST35
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3089 – 3130TowerInterPro annotationAdd BLAST42

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni40 – 68DisorderedSequence analysisAdd BLAST29
Regioni440 – 460DisorderedSequence analysisAdd BLAST21
Regioni1726 – 1749DisorderedSequence analysisAdd BLAST24
Regioni2686 – 2706DisorderedSequence analysisAdd BLAST21
Regioni3648 – 3675DisorderedSequence analysisAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili3113 – 3137Sequence analysisAdd BLAST25
Coiled coili3417 – 3437Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00390000003602

Identification of Orthologs from Complete Genome Data

More...OMAi		KMEQNIK

Family and domain databases

Conserved Domains Database

More...CDDi		cd04493, BRCA2DBD_OB1, 1 hit
cd04495, BRCA2DBD_OB3, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR015525, BRCA2
IPR015252, BRCA2_hlx
IPR036315, BRCA2_hlx_sf
IPR015187, BRCA2_OB_1
IPR015188, BRCA2_OB_3
IPR002093, BRCA2_repeat
IPR012340, NA-bd_OB-fold
IPR015205, Tower_dom

The PANTHER Classification System

More...PANTHERi		PTHR11289, PTHR11289, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF09169, BRCA-2_helical, 1 hit
PF09103, BRCA-2_OB1, 1 hit
PF09104, BRCA-2_OB3, 1 hit
PF00634, BRCA2, 8 hits
PF09121, Tower, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF002397, BRCA2, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01341, Tower, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50249, SSF50249, 3 hits
SSF81872, SSF81872, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50138, BRCA2_REPEAT, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2K5ZBS6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSIGSKERPT FFEIFKTRCN KADLGPISLN WFEELSSEAA PYNSEPAEDS 
        60         70         80         90        100
EHKNNSYEPN LFKTPQRKPS YNQLASTPII FKERGLTLPP YQSPVKELDT 
       110        120        130        140        150
FRLDLGRNVP SSRHKSLRTV KAEMHQADDV TCPLLNSCLS ESPVVLQCTH 
       160        170        180        190        200
VTPQRNKSVV CGSLFHTPKF VKGRQTPKHI SESLGAEVDP DMSWSSSLAT 
       210        220        230        240        250
PPTLSSTVLI VRNEEASETL FPHDTTANVK SYFSNHDKSL KKNDRCIPSV 
       260        270        280        290        300
TDSENTNQRE ATSHRFGRTL GNSFKVNSCK DHIGKSMPNV LEDEVYETVV 
       310        320        330        340        350
DTSEEDSFSL CFSKCRTGNL QKVRTSKTRK KIFREANADE CEKSKNQVKE 
       360        370        380        390        400
KYSFVSEMES SDTDPLDSNV ANQKPFESGS DKISKEVVPS LACEWSQLTL 
       410        420        430        440        450
SGLDGTQMEK IPLLHISSCD QNNSEKDLLN TENERKKDFL TSENSLPHIS 
       460        470        480        490        500
SLPKSEKPLN EETVVNKRDE EQHLESHRDY ILAVKQAVSE TSPMASSFQG 
       510        520        530        540        550
IKKSIFRIRE SPKEIFNASF SGHVTDPNFK KETKASESGL EIHTVCSRKD 
       560        570        580        590        600
DSLCPNSIDN GSWPAATTQT SVASKNAGLI STLKKKTNKF IYAIHDETSY 
       610        620        630        640        650
QGKKMPKDQK SELMNCSAQF EANAFEAPLT FANADSGLFH SSVKRSCSQN 
       660        670        680        690        700
YSEEPTLSLT SSFGTILRKC SRNETCSSNN TIISQDLDYK EAKCNKKELQ 
       710        720        730        740        750
LFITPEADSL SFLQEGQYEN DPKSRKVSDI KEEVLAAAHH PVQHSKAEYS 
       760        770        780        790        800
DTDFQSQESP LYDHENASTL ILTPTSKDVL SNLVMISRGK ESYKMSDELK 
       810        820        830        840        850
GNNYESDFEL TKNIPMEKNQ DVCALSENSK HVELLPPEKY IRVASPSRKV 
       860        870        880        890        900
QFNQNTNLRV IQKDQEEPTL IPKITVNPDS EELFSDNENN FVFQVVNERN 
       910        920        930        940        950
NFALGNTKEL HETDLTCVNE PIFKNSTMVL YADIGDKQAT QVSIKKDLDS 
       960        970        980        990       1000
SNIVYDLAEE NKNSVKQHLK MTLGQDLQPD ILNIDKIADK NNDCMDKWAG 
      1010       1020       1030       1040       1050
PLDPISNHSF GGSFRTASNK EIKVSEHNIK KSKMFFKDIE EQYPTSLACV 
      1060       1070       1080       1090       1100
EIVNTLALDN QKKLSKPQSI NTVSAQIQSS VVVSDCKNSH ITPQMSFSKQ 
      1110       1120       1130       1140       1150
DFNSNHNLTP SQKAEITELS TILEESGSQF EFTQFRKPSY ILQKNTFEVP 
      1160       1170       1180       1190       1200
ENQVTILNTT SAENRDAGLV IMNAPSIGQV DSSKQFEGTV GIKQKFAGLL 
      1210       1220       1230       1240       1250
KNDCNKSASG YLTDENEVEF RGFYSAHGVK LNVSTEALQK AVKLFSDIEN 
      1260       1270       1280       1290       1300
ISEETSAEVD PISLSSSKFH DSVVSMFKIE NHNDKTVSGK NKCQLMLQNN 
      1310       1320       1330       1340       1350
IEMTTGTFVE EITENYKINT ENEDNKYTAA SRNSRNLEFV GSDSSKNDTV 
      1360       1370       1380       1390       1400
CIHKDEKDLP FTDQHNICLK LSGQFMKEGN TQIKEGLSHL TFLEVVKAQE 
      1410       1420       1430       1440       1450
TCHGNTSNKE QLTATKTEQN IKDFETFDIS FQTASGKNIS VTKESFNKIV 
      1460       1470       1480       1490       1500
NFFDPKPEEL HNFSLNSKLH SDIRKNKMDI LSHEETDTVK NKILKESVPV 
      1510       1520       1530       1540       1550
GTGNQLVTFQ ERPQGDEKIK EPTLLGFHTA SGKKVKITKE SLDKVKNLFD 
      1560       1570       1580       1590       1600
EKEQGASEIT SFSHQWAKTL KYREACKDLE LACETVEITT APKCKEMQNS 
      1610       1620       1630       1640       1650
LNNDKNLVSI ETVVPPKLLS DHLCRQTENL KTSKSIFLKV KVHENVEKET 
      1660       1670       1680       1690       1700
AKSPATCYTN QSPYSVIENS ALAFYTSCSR KRSVSQTSLL EAKQWLREGI 
      1710       1720       1730       1740       1750
FDDQPERINT ADYVGNSLYE NNSKNTIAES DKNHPSKKQD TTLNNSSMSN 
      1760       1770       1780       1790       1800
SYSYLSDEVY SDSGYLSKNK LDSGIEPVLK KVEDQKNTSF SKVISSVKDA 
      1810       1820       1830       1840       1850
NTYPQTVNEG ICVEELVTSS SPCKNKNAAI KVSISNCNNF EVGPPAFSTA 
      1860       1870       1880       1890       1900
SGKIICVSHE TIKKVKEIFT DSFGKVIKEN NENKSNICQT KIVAGRYEAL 
      1910       1920       1930       1940       1950
DDSEDIFHNS LDSDECSMHS HKVFADIQSE EILQHNQNMS GLEQVSKVSP 
      1960       1970       1980       1990       2000
CDVSLETSDI CKCSIGKFPK SVPSTNICGI FSTASGKSVQ VSDASLQKAR 
      2010       2020       2030       2040       2050
QVFSEIKDST KQVCSKVLFK SNEHSDQLTR EENTTIHTPK HLISSQKDFS 
      2060       2070       2080       2090       2100
YNVVNSSVFS GFSTASGKQV SISESSLHKV KGMLEEFDII RTEHSLHYSP 
      2110       2120       2130       2140       2150
TSRQNVSKIL PCVDKRTPEH CVNSEMEKAC SKEFNLSNNF NVEGGSSENN 
      2160       2170       2180       2190       2200
HSIKVSPSLS QFKQDKQQLC SMHSHKVFAD IQSEEILQHN QNMSGLEQVS 
      2210       2220       2230       2240       2250
KVSPCDVSLE TSDICKCSIG KFPKSVPSTN ICGIFSTASG KSVQVSDASL 
      2260       2270       2280       2290       2300
QKARQVFSEI KDSTKQVCSK VLFKSNEHSD QLTREENTTI HTPKHLISSQ 
      2310       2320       2330       2340       2350
KDFSYNVVNS SVFSGFSTAS GKQVSISESS LHKVKGMLEE FDIIRTEHSL 
      2360       2370       2380       2390       2400
HYSPTSRQNV SKILPCVDKR TPEHCVNSEM EKACSKEFNL SNNFNVEGGS 
      2410       2420       2430       2440       2450
SENNHSIKVS PSLSQFKQDK QQLVLGTKVS LVENIHVLGK EQASPENVKM 
      2460       2470       2480       2490       2500
EIGKTEAFSD VPVKTNIEVC STYSKDSENY FETEAVEIAK AFMEDGELTD 
      2510       2520       2530       2540       2550
SELPSHATHS LFTRPQNEEM VLSNSRIGKR RGEALISAGE PPIKRNLLNE 
      2560       2570       2580       2590       2600
FDRIIENQEK SLKPSKSTPD GTIKDRRLFM HHVSLEPITC VPFCTTKERQ 
      2610       2620       2630       2640       2650
EIQNPNFTAP GQEFLSKSHL YEHLTLEKSS SNLAVSGHPF YQVSATRNEK 
      2660       2670       2680       2690       2700
MRHLITTGKP TKVFIPPFKT KSHFHRDEQC VRNINLEENK QKQNIDGHGS 
      2710       2720       2730       2740       2750
GDSKNKINDN EIHHFNKNNS NQAATVIFTK CEEEPLDLIT SLQNARDIQD 
      2760       2770       2780       2790       2800
MRIKKKQRQR IFPQPGSLYL AKTSTLPRIS LKAAVGGQVP SACSHKQLYM 
      2810       2820       2830       2840       2850
YGVSKHCIKI NSKNAESFQF YTQDYFGKES LWAGKGIQLA DGGWLIPSND 
      2860       2870       2880       2890       2900
GKAGKEEFYR ALCDTPGVDP KLISRIWVYN HYRWIIWKLA AMECAFPKEF 
      2910       2920       2930       2940       2950
ANRCLSPERV LLQLKYRYDM EIDRSRRSAI KKIMERDDTA AKTLVLCVSD 
      2960       2970       2980       2990       3000
IISLSANISE TSSNKTSSAD TQKVAIIELT DGWYAVKAQL DPPLLAVLKN 
      3010       3020       3030       3040       3050
GRVTVGQKII LHGAELVGSP DACTPLEAPA SLMLKISANS TRPARWYTKL 
      3060       3070       3080       3090       3100
GFFPDPRPFP LPLSSLFSDG GNVGCVDVII QRAYPIQWME KTSSGLYIFR 
      3110       3120       3130       3140       3150
NEREEEKEAA KYVEAQQKRL EALFTKIQEE FEEHEENTTK PYLPSRALTR 
      3160       3170       3180       3190       3200
QQVRALQDGA ELYEAVKNAA DPAYLEGYFS EEQLRALNNH RQMLNDKKQA 
      3210       3220       3230       3240       3250
QIQLEIRKAM ESAEQKEQGL SRDVTTVWKL RIVSYSKKEK DSVILSIWRP 
      3260       3270       3280       3290       3300
SSDLYSLLTE GKRYRIYHLA TSKSKSKSER ANIQLAATKK TQYQQLPVSD 
      3310       3320       3330       3340       3350
EILFQVYQPR EPLHFSKFLD PDFQPSFSEV DLIGFVVSVV KKTGLAPFIY 
      3360       3370       3380       3390       3400
LSDECYNLLA IKFWIDLNED IIKPHMLIAA SNLQWRPESK SGLPTLFAGD 
      3410       3420       3430       3440       3450
FSVFSTSPKE GHFQETFNKM KNTVENIDIL CNEAENKLMH ILHANDPKWS 
      3460       3470       3480       3490       3500
TPIKDWTSES YTAQIIPGTG NKLLISSPNC ELYYQSPLSL CMAKRKSVST 
      3510       3520       3530       3540       3550
PVSAQITSKS CEGEKEIDDQ KSCKRRRALD FLSRLPLPPP VSPICTFVSP 
      3560       3570       3580       3590       3600
AAQKAFQPPR SCGTKYQTPI KKKELNSPQM TPFKKFNEIS LSESNSIADE 
      3610       3620       3630       3640       3650
ELALINTQAL LSGSTGEKQF ISVSESTRTT PTSSEDYLRR KRRCATSLIK 
      3660       3670 
EQERSRSGKE ECENNRQDTI TAKKY
Length:3,675
Mass (Da):412,687
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFF19EA84D246DBC4
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMLET00000048796; ENSMLEP00000025266; ENSMLEG00000036824

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSMLET00000048796; ENSMLEP00000025266; ENSMLEG00000036824

Phylogenomic databases

GeneTreeiENSGT00390000003602
OMAiKMEQNIK

Family and domain databases

CDDicd04493, BRCA2DBD_OB1, 1 hit
cd04495, BRCA2DBD_OB3, 1 hit
InterProiView protein in InterPro
IPR015525, BRCA2
IPR015252, BRCA2_hlx
IPR036315, BRCA2_hlx_sf
IPR015187, BRCA2_OB_1
IPR015188, BRCA2_OB_3
IPR002093, BRCA2_repeat
IPR012340, NA-bd_OB-fold
IPR015205, Tower_dom
PANTHERiPTHR11289, PTHR11289, 2 hits
PfamiView protein in Pfam
PF09169, BRCA-2_helical, 1 hit
PF09103, BRCA-2_OB1, 1 hit
PF09104, BRCA-2_OB3, 1 hit
PF00634, BRCA2, 8 hits
PF09121, Tower, 1 hit
PIRSFiPIRSF002397, BRCA2, 2 hits
SMARTiView protein in SMART
SM01341, Tower, 1 hit
SUPFAMiSSF50249, SSF50249, 3 hits
SSF81872, SSF81872, 1 hit
PROSITEiView protein in PROSITE
PS50138, BRCA2_REPEAT, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2K5ZBS6_MANLE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2K5ZBS6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: February 10, 2021
This is version 18 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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