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Entry version 18 (10 Feb 2021)
Sequence version 1 (28 Mar 2018)
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Protein

Tower domain-containing protein

Gene

BRCA2

Organism
Mandrillus leucophaeus (Drill) (Papio leucophaeus)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingARBA annotation
Biological processDNA damage, DNA recombinationARBA annotation, DNA repairARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tower domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BRCA2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMandrillus leucophaeus (Drill) (Papio leucophaeus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9568 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMandrillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000233140 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1007 – 1041BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1216 – 1250BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1424 – 1458BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1520 – 1554BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1667 – 1701BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1840 – 1874BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1974 – 2008BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati2055 – 2089BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati2228 – 2262BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati2309 – 2343BRCA2PROSITE-ProRule annotationAdd BLAST35
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3089 – 3130TowerInterPro annotationAdd BLAST42

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni40 – 68DisorderedSequence analysisAdd BLAST29
Regioni440 – 460DisorderedSequence analysisAdd BLAST21
Regioni1726 – 1749DisorderedSequence analysisAdd BLAST24
Regioni2686 – 2706DisorderedSequence analysisAdd BLAST21
Regioni3648 – 3675DisorderedSequence analysisAdd BLAST28

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili3113 – 3137Sequence analysisAdd BLAST25
Coiled coili3417 – 3437Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000003602

Identification of Orthologs from Complete Genome Data

More...
OMAi
KMEQNIK

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04493, BRCA2DBD_OB1, 1 hit
cd04495, BRCA2DBD_OB3, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015525, BRCA2
IPR015252, BRCA2_hlx
IPR036315, BRCA2_hlx_sf
IPR015187, BRCA2_OB_1
IPR015188, BRCA2_OB_3
IPR002093, BRCA2_repeat
IPR012340, NA-bd_OB-fold
IPR015205, Tower_dom

The PANTHER Classification System

More...
PANTHERi
PTHR11289, PTHR11289, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09169, BRCA-2_helical, 1 hit
PF09103, BRCA-2_OB1, 1 hit
PF09104, BRCA-2_OB3, 1 hit
PF00634, BRCA2, 8 hits
PF09121, Tower, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002397, BRCA2, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01341, Tower, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50249, SSF50249, 3 hits
SSF81872, SSF81872, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50138, BRCA2_REPEAT, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2K5ZBS6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSIGSKERPT FFEIFKTRCN KADLGPISLN WFEELSSEAA PYNSEPAEDS
60 70 80 90 100
EHKNNSYEPN LFKTPQRKPS YNQLASTPII FKERGLTLPP YQSPVKELDT
110 120 130 140 150
FRLDLGRNVP SSRHKSLRTV KAEMHQADDV TCPLLNSCLS ESPVVLQCTH
160 170 180 190 200
VTPQRNKSVV CGSLFHTPKF VKGRQTPKHI SESLGAEVDP DMSWSSSLAT
210 220 230 240 250
PPTLSSTVLI VRNEEASETL FPHDTTANVK SYFSNHDKSL KKNDRCIPSV
260 270 280 290 300
TDSENTNQRE ATSHRFGRTL GNSFKVNSCK DHIGKSMPNV LEDEVYETVV
310 320 330 340 350
DTSEEDSFSL CFSKCRTGNL QKVRTSKTRK KIFREANADE CEKSKNQVKE
360 370 380 390 400
KYSFVSEMES SDTDPLDSNV ANQKPFESGS DKISKEVVPS LACEWSQLTL
410 420 430 440 450
SGLDGTQMEK IPLLHISSCD QNNSEKDLLN TENERKKDFL TSENSLPHIS
460 470 480 490 500
SLPKSEKPLN EETVVNKRDE EQHLESHRDY ILAVKQAVSE TSPMASSFQG
510 520 530 540 550
IKKSIFRIRE SPKEIFNASF SGHVTDPNFK KETKASESGL EIHTVCSRKD
560 570 580 590 600
DSLCPNSIDN GSWPAATTQT SVASKNAGLI STLKKKTNKF IYAIHDETSY
610 620 630 640 650
QGKKMPKDQK SELMNCSAQF EANAFEAPLT FANADSGLFH SSVKRSCSQN
660 670 680 690 700
YSEEPTLSLT SSFGTILRKC SRNETCSSNN TIISQDLDYK EAKCNKKELQ
710 720 730 740 750
LFITPEADSL SFLQEGQYEN DPKSRKVSDI KEEVLAAAHH PVQHSKAEYS
760 770 780 790 800
DTDFQSQESP LYDHENASTL ILTPTSKDVL SNLVMISRGK ESYKMSDELK
810 820 830 840 850
GNNYESDFEL TKNIPMEKNQ DVCALSENSK HVELLPPEKY IRVASPSRKV
860 870 880 890 900
QFNQNTNLRV IQKDQEEPTL IPKITVNPDS EELFSDNENN FVFQVVNERN
910 920 930 940 950
NFALGNTKEL HETDLTCVNE PIFKNSTMVL YADIGDKQAT QVSIKKDLDS
960 970 980 990 1000
SNIVYDLAEE NKNSVKQHLK MTLGQDLQPD ILNIDKIADK NNDCMDKWAG
1010 1020 1030 1040 1050
PLDPISNHSF GGSFRTASNK EIKVSEHNIK KSKMFFKDIE EQYPTSLACV
1060 1070 1080 1090 1100
EIVNTLALDN QKKLSKPQSI NTVSAQIQSS VVVSDCKNSH ITPQMSFSKQ
1110 1120 1130 1140 1150
DFNSNHNLTP SQKAEITELS TILEESGSQF EFTQFRKPSY ILQKNTFEVP
1160 1170 1180 1190 1200
ENQVTILNTT SAENRDAGLV IMNAPSIGQV DSSKQFEGTV GIKQKFAGLL
1210 1220 1230 1240 1250
KNDCNKSASG YLTDENEVEF RGFYSAHGVK LNVSTEALQK AVKLFSDIEN
1260 1270 1280 1290 1300
ISEETSAEVD PISLSSSKFH DSVVSMFKIE NHNDKTVSGK NKCQLMLQNN
1310 1320 1330 1340 1350
IEMTTGTFVE EITENYKINT ENEDNKYTAA SRNSRNLEFV GSDSSKNDTV
1360 1370 1380 1390 1400
CIHKDEKDLP FTDQHNICLK LSGQFMKEGN TQIKEGLSHL TFLEVVKAQE
1410 1420 1430 1440 1450
TCHGNTSNKE QLTATKTEQN IKDFETFDIS FQTASGKNIS VTKESFNKIV
1460 1470 1480 1490 1500
NFFDPKPEEL HNFSLNSKLH SDIRKNKMDI LSHEETDTVK NKILKESVPV
1510 1520 1530 1540 1550
GTGNQLVTFQ ERPQGDEKIK EPTLLGFHTA SGKKVKITKE SLDKVKNLFD
1560 1570 1580 1590 1600
EKEQGASEIT SFSHQWAKTL KYREACKDLE LACETVEITT APKCKEMQNS
1610 1620 1630 1640 1650
LNNDKNLVSI ETVVPPKLLS DHLCRQTENL KTSKSIFLKV KVHENVEKET
1660 1670 1680 1690 1700
AKSPATCYTN QSPYSVIENS ALAFYTSCSR KRSVSQTSLL EAKQWLREGI
1710 1720 1730 1740 1750
FDDQPERINT ADYVGNSLYE NNSKNTIAES DKNHPSKKQD TTLNNSSMSN
1760 1770 1780 1790 1800
SYSYLSDEVY SDSGYLSKNK LDSGIEPVLK KVEDQKNTSF SKVISSVKDA
1810 1820 1830 1840 1850
NTYPQTVNEG ICVEELVTSS SPCKNKNAAI KVSISNCNNF EVGPPAFSTA
1860 1870 1880 1890 1900
SGKIICVSHE TIKKVKEIFT DSFGKVIKEN NENKSNICQT KIVAGRYEAL
1910 1920 1930 1940 1950
DDSEDIFHNS LDSDECSMHS HKVFADIQSE EILQHNQNMS GLEQVSKVSP
1960 1970 1980 1990 2000
CDVSLETSDI CKCSIGKFPK SVPSTNICGI FSTASGKSVQ VSDASLQKAR
2010 2020 2030 2040 2050
QVFSEIKDST KQVCSKVLFK SNEHSDQLTR EENTTIHTPK HLISSQKDFS
2060 2070 2080 2090 2100
YNVVNSSVFS GFSTASGKQV SISESSLHKV KGMLEEFDII RTEHSLHYSP
2110 2120 2130 2140 2150
TSRQNVSKIL PCVDKRTPEH CVNSEMEKAC SKEFNLSNNF NVEGGSSENN
2160 2170 2180 2190 2200
HSIKVSPSLS QFKQDKQQLC SMHSHKVFAD IQSEEILQHN QNMSGLEQVS
2210 2220 2230 2240 2250
KVSPCDVSLE TSDICKCSIG KFPKSVPSTN ICGIFSTASG KSVQVSDASL
2260 2270 2280 2290 2300
QKARQVFSEI KDSTKQVCSK VLFKSNEHSD QLTREENTTI HTPKHLISSQ
2310 2320 2330 2340 2350
KDFSYNVVNS SVFSGFSTAS GKQVSISESS LHKVKGMLEE FDIIRTEHSL
2360 2370 2380 2390 2400
HYSPTSRQNV SKILPCVDKR TPEHCVNSEM EKACSKEFNL SNNFNVEGGS
2410 2420 2430 2440 2450
SENNHSIKVS PSLSQFKQDK QQLVLGTKVS LVENIHVLGK EQASPENVKM
2460 2470 2480 2490 2500
EIGKTEAFSD VPVKTNIEVC STYSKDSENY FETEAVEIAK AFMEDGELTD
2510 2520 2530 2540 2550
SELPSHATHS LFTRPQNEEM VLSNSRIGKR RGEALISAGE PPIKRNLLNE
2560 2570 2580 2590 2600
FDRIIENQEK SLKPSKSTPD GTIKDRRLFM HHVSLEPITC VPFCTTKERQ
2610 2620 2630 2640 2650
EIQNPNFTAP GQEFLSKSHL YEHLTLEKSS SNLAVSGHPF YQVSATRNEK
2660 2670 2680 2690 2700
MRHLITTGKP TKVFIPPFKT KSHFHRDEQC VRNINLEENK QKQNIDGHGS
2710 2720 2730 2740 2750
GDSKNKINDN EIHHFNKNNS NQAATVIFTK CEEEPLDLIT SLQNARDIQD
2760 2770 2780 2790 2800
MRIKKKQRQR IFPQPGSLYL AKTSTLPRIS LKAAVGGQVP SACSHKQLYM
2810 2820 2830 2840 2850
YGVSKHCIKI NSKNAESFQF YTQDYFGKES LWAGKGIQLA DGGWLIPSND
2860 2870 2880 2890 2900
GKAGKEEFYR ALCDTPGVDP KLISRIWVYN HYRWIIWKLA AMECAFPKEF
2910 2920 2930 2940 2950
ANRCLSPERV LLQLKYRYDM EIDRSRRSAI KKIMERDDTA AKTLVLCVSD
2960 2970 2980 2990 3000
IISLSANISE TSSNKTSSAD TQKVAIIELT DGWYAVKAQL DPPLLAVLKN
3010 3020 3030 3040 3050
GRVTVGQKII LHGAELVGSP DACTPLEAPA SLMLKISANS TRPARWYTKL
3060 3070 3080 3090 3100
GFFPDPRPFP LPLSSLFSDG GNVGCVDVII QRAYPIQWME KTSSGLYIFR
3110 3120 3130 3140 3150
NEREEEKEAA KYVEAQQKRL EALFTKIQEE FEEHEENTTK PYLPSRALTR
3160 3170 3180 3190 3200
QQVRALQDGA ELYEAVKNAA DPAYLEGYFS EEQLRALNNH RQMLNDKKQA
3210 3220 3230 3240 3250
QIQLEIRKAM ESAEQKEQGL SRDVTTVWKL RIVSYSKKEK DSVILSIWRP
3260 3270 3280 3290 3300
SSDLYSLLTE GKRYRIYHLA TSKSKSKSER ANIQLAATKK TQYQQLPVSD
3310 3320 3330 3340 3350
EILFQVYQPR EPLHFSKFLD PDFQPSFSEV DLIGFVVSVV KKTGLAPFIY
3360 3370 3380 3390 3400
LSDECYNLLA IKFWIDLNED IIKPHMLIAA SNLQWRPESK SGLPTLFAGD
3410 3420 3430 3440 3450
FSVFSTSPKE GHFQETFNKM KNTVENIDIL CNEAENKLMH ILHANDPKWS
3460 3470 3480 3490 3500
TPIKDWTSES YTAQIIPGTG NKLLISSPNC ELYYQSPLSL CMAKRKSVST
3510 3520 3530 3540 3550
PVSAQITSKS CEGEKEIDDQ KSCKRRRALD FLSRLPLPPP VSPICTFVSP
3560 3570 3580 3590 3600
AAQKAFQPPR SCGTKYQTPI KKKELNSPQM TPFKKFNEIS LSESNSIADE
3610 3620 3630 3640 3650
ELALINTQAL LSGSTGEKQF ISVSESTRTT PTSSEDYLRR KRRCATSLIK
3660 3670
EQERSRSGKE ECENNRQDTI TAKKY
Length:3,675
Mass (Da):412,687
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFF19EA84D246DBC4
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMLET00000048796; ENSMLEP00000025266; ENSMLEG00000036824

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSMLET00000048796; ENSMLEP00000025266; ENSMLEG00000036824

Phylogenomic databases

GeneTreeiENSGT00390000003602
OMAiKMEQNIK

Family and domain databases

CDDicd04493, BRCA2DBD_OB1, 1 hit
cd04495, BRCA2DBD_OB3, 1 hit
InterProiView protein in InterPro
IPR015525, BRCA2
IPR015252, BRCA2_hlx
IPR036315, BRCA2_hlx_sf
IPR015187, BRCA2_OB_1
IPR015188, BRCA2_OB_3
IPR002093, BRCA2_repeat
IPR012340, NA-bd_OB-fold
IPR015205, Tower_dom
PANTHERiPTHR11289, PTHR11289, 2 hits
PfamiView protein in Pfam
PF09169, BRCA-2_helical, 1 hit
PF09103, BRCA-2_OB1, 1 hit
PF09104, BRCA-2_OB3, 1 hit
PF00634, BRCA2, 8 hits
PF09121, Tower, 1 hit
PIRSFiPIRSF002397, BRCA2, 2 hits
SMARTiView protein in SMART
SM01341, Tower, 1 hit
SUPFAMiSSF50249, SSF50249, 3 hits
SSF81872, SSF81872, 1 hit
PROSITEiView protein in PROSITE
PS50138, BRCA2_REPEAT, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2K5ZBS6_MANLE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2K5ZBS6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: February 10, 2021
This is version 18 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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