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Entry version 9 (31 Jul 2019)
Sequence version 1 (28 Mar 2018)
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Protein
Submitted name:

Uncharacterized protein

Gene

KIAA2012

Organism
Mandrillus leucophaeus (Drill) (Papio leucophaeus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KIAA2012Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMandrillus leucophaeus (Drill) (Papio leucophaeus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9568 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMandrillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000233140 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Whole Genome Shotgun Assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni229 – 274DisorderedSequence analysisAdd BLAST46
Regioni433 – 562DisorderedSequence analysisAdd BLAST130
Regioni774 – 951DisorderedSequence analysisAdd BLAST178
Regioni964 – 983DisorderedSequence analysisAdd BLAST20
Regioni1049 – 1072DisorderedSequence analysisAdd BLAST24

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi442 – 459PolyampholyteSequence analysisAdd BLAST18
Compositional biasi517 – 531PolarSequence analysisAdd BLAST15
Compositional biasi774 – 802PolyampholyteSequence analysisAdd BLAST29
Compositional biasi812 – 837PolyampholyteSequence analysisAdd BLAST26
Compositional biasi838 – 852BasicSequence analysisAdd BLAST15
Compositional biasi900 – 925PolarSequence analysisAdd BLAST26
Compositional biasi926 – 951PolyampholyteSequence analysisAdd BLAST26

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00860000133854

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031440 DUF4670

The PANTHER Classification System

More...
PANTHERi
PTHR21937 PTHR21937, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15709 DUF4670, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2K5Y835-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFTLSLLSRG HGKLGQDKQK LEVYFEPEDY LNWRSPEDYV PVSKPQDKNN
60 70 80 90 100
ANQHSWSLFL PKTFSTRKGA LILYSEGLAI SAWTPKERRK GLYRPKGPWR
110 120 130 140 150
KLDLELHTLQ DLQEAILAYG RQQGQQDRAW QPYLHFRSQL ESQAQRQIQP
160 170 180 190 200
GHSAKRYLRG LLRTWPPDAM YRLWCSGYIK DSVLLQDSQL NVPKKLRPQQ
210 220 230 240 250
DLSGVPPKYH LLPVFPSFWI QQGKSFEQGQ QGLDEGEAGA AGHVDQGPLA
260 270 280 290 300
KNHGSQGTRL PPLRKQPWQE DETWAEDTSI ENHLHLYASK ERYNEKTQQT
310 320 330 340 350
FRKAFGHGHI DYSCLPSDKS HIMFCGGTFP NRKADLSDKQ RNVKLHKARS
360 370 380 390 400
GHLLQSLPAE RCLFPPVASA TGSGIITPGE VKKKKAPKAL KLPPISEEPP
410 420 430 440 450
RVLEPLKSQF KANEPPTELF IFPVEIHYHI QHPPKEKAHR RGAPHPKSEP
460 470 480 490 500
ERSEEARPVW KPPLKPVSLE TPRELTVHLP VDAGRDTLSP QDDDAPPHDA
510 520 530 540 550
APPLDLLPPI KGKKSPESQN GLDSPRTSGR SSPPCLPHMR ASRRALPAAQ
560 570 580 590 600
EDSSDPTLGH FLLGPDGEEV CLSLPGQTQT EALPSGKAYE SVNSNISHKE
610 620 630 640 650
DGPSSQHFLK ANTEPRANLH MNLYETSPLT QTTEKQGAQQ SLEAAAQKTE
660 670 680 690 700
EPQSCINKGL ICSNRKEFYT RKLHIDMTPF LKESGNALDS QEEAGRLLRE
710 720 730 740 750
THHDGQDSEP KSMTLDSLRA SQTEHIRTPE ADIVQKVGRD YDIHHLHKGL
760 770 780 790 800
LGYGPESPKK LSAVYTSLLP REREGKAEPR LFSRETSASI SHERDLIDKS
810 820 830 840 850
KRKKRPKKDK TKGPKREREG KVYGEAEAAI GKSKDSKAKK KLEKKTRPQR
860 870 880 890 900
KRTQKERNLE TAAELSGPDV NSDETEDTSN RGSFASDSFV EDPWLSPKYD
910 920 930 940 950
AQETQVSLDG RSSPSQIATV TGNMESKEER SCEDPSKALL TKRQQEKASW
960 970 980 990 1000
DRLRAEKAET RWLEVEKKRR EQEEQRQLQQ EQLERAKKME EELELDQQRR
1010 1020 1030 1040 1050
AEEIRLRKQR LQEEQQRQEE EERKQQLWLK AAQERARQQQ EEFRRKLREL
1060 1070 1080 1090 1100
QRKKQQEEAE RAEAEKQRQK ELEMQLAEEQ KRLMEMAEEE RLEYQRRKQE
1110 1120 1130 1140 1150
EEKAQLEAEE RRQKEVEAAR LALEEATKQA QEQARQKAAL KKHLHFHQEL
1160 1170 1180
RKEASGLQWT HNISRPWVYS YFQFLQIPRP
Length:1,180
Mass (Da):135,639
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i076E924C6974AD7A
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMLET00000035156; ENSMLEP00000011731; ENSMLEG00000030041

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMLET00000035156; ENSMLEP00000011731; ENSMLEG00000030041

Phylogenomic databases

GeneTreeiENSGT00860000133854

Family and domain databases

InterProiView protein in InterPro
IPR031440 DUF4670
PANTHERiPTHR21937 PTHR21937, 1 hit
PfamiView protein in Pfam
PF15709 DUF4670, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2K5Y835_MANLE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2K5Y835
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: July 31, 2019
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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