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Protein
Submitted name:

Rho GTPase activating protein 4

Gene

ARHGAP4

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGTPase activationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Rho GTPase activating protein 4Imported
Gene namesi
Name:ARHGAP4Imported
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 317F-BARInterPro annotationAdd BLAST299
Domaini507 – 695Rho-GAPInterPro annotationAdd BLAST189
Domaini746 – 805SH3InterPro annotationAdd BLAST60

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili42 – 62Sequence analysisAdd BLAST21
Coiled coili150 – 191Sequence analysisAdd BLAST42
Coiled coili454 – 477Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118863

Family and domain databases

CDDicd11956 SH3_srGAP4, 1 hit
Gene3Di1.10.555.10, 1 hit
1.20.1270.60, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR031160 F_BAR
IPR001060 FCH_dom
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR035678 srGAP4_SH3
PfamiView protein in Pfam
PF00611 FCH, 1 hit
PF00620 RhoGAP, 1 hit
PF00018 SH3_1, 1 hit
SMARTiView protein in SMART
SM00055 FCH, 1 hit
SM00324 RhoGAP, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 2 hits
SSF48350 SSF48350, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS51741 F_BAR, 1 hit
PS50238 RHOGAP, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K5WP83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAHGKLRRE RGLQAEYETQ VKEMRWQLSE QLRCLELQGE LRRELLQELA
60 70 80 90 100
EFMRRRAEVE LEYSRGLEKL AERFSSRGGR LGSSREHQSF RKEPSLLSPL
110 120 130 140 150
HCWAVLLQHT RQQSRESAAL SEVLAGPLAQ RLSHIAEDVG RLVKKSRDLE
160 170 180 190 200
QQLQDELLEV VSELQTAKKT YQAYHMESVN AEAKLREAER QEEKRAGRSV
210 220 230 240 250
PTTTAAATEA GPLRKSSLKK GGRLVEKRQA KFMEHKLKCT KARNEYLLSL
260 270 280 290 300
ASVNAAVSNY YLHDVLDLMD CCDTGFHLAL GQVLRSYMAA ESRTQASQVQ
310 320 330 340 350
GLGSLEEAVE ALDPSGDKAK VLEVHATIFC PPLRFDYHPH DGDEVAEICV
360 370 380 390 400
EMELQDEILP RAQNIQSRLD RQTIETEEVN KTLKATLQAL LEVVASDDGD
410 420 430 440 450
VLDSFQTSPS TESLKSTSSD PGSRQAGRRR GQQQETETFY LTKLQEYLSG
460 470 480 490 500
RSILAKLQAK HEKLQEALQR GDKEEREMSW TQYTQRKFQK SRHPRPSSQY
510 520 530 540 550
NQRLFGGDME KFIQCSGQPV PLVVESCIRF INLNGLQHEG IFRVSGAQLR
560 570 580 590 600
VSEIRDAFER GEDPLVEGCT AHDLDSVAGV LKLYFRSLEP PLFPPDLFSE
610 620 630 640 650
LLASSELEAT AERVEHVSRL LWRLPAPVLV VLRYLFNFLN HLAQYSDENM
660 670 680 690 700
MDPYNLAVCF GPTLLPVPAG QDPVALQGRV NQLVQTLILQ PDRVFPPLTS
710 720 730 740 750
LPGPVYEKCM APPSASCLGD AQLESLGADN EPELEAEMLA QEDDLEGVVE
760 770 780 790 800
AVACFAYTGR TAQELSFRRG DVLRLHERAS SDWWRGEHNG VRGLIPHKYI
810 820 830 840 850
TLPEGAEKQV VGAGPQTAGE SGSSPEGLLA SELVHRPEPC ISPEAVGLSG
860 870 880 890 900
HRRRCLVPAS PEQHVEVDKA VAQNMDSVFK ELLGKTSVRQ GLGPASATSP
910 920 930 940
SPGPRSPKAP AGSRLGKNKG FSRGPGAPAS PSASHPQGLD TTPKPH
Length:946
Mass (Da):105,066
Last modified:March 28, 2018 - v1
Checksum:i7AAAE2347AFE50D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01087615 Genomic DNA No translation available.
AQIA01087616 Genomic DNA No translation available.
RefSeqiXP_005595003.1, XM_005594946.2

Genome annotation databases

EnsembliENSMFAT00000013199; ENSMFAP00000038940; ENSMFAG00000038733
GeneIDi102129586

Similar proteinsi

Entry informationi

Entry nameiA0A2K5WP83_MACFA
AccessioniPrimary (citable) accession number: A0A2K5WP83
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: July 18, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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