Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

RBR-type E3 ubiquitin transferase

Gene

RNF217

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RBR-type E3 ubiquitin transferaseSAAS annotation (EC:2.3.2.31SAAS annotation)
Gene namesi
Name:RNF217Imported
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei499 – 528HelicalSequence analysisAdd BLAST30

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini328 – 396IBR-typeInterPro annotationAdd BLAST69
Domaini403 – 474IBR-typeInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the RBR family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis, Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00730000111285
KOiK11977

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR031127 E3_UB_ligase_RBR
IPR002867 IBR_dom
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR11685 PTHR11685, 1 hit
PfamiView protein in Pfam
PF01485 IBR, 2 hits
SMARTiView protein in SMART
SM00647 IBR, 2 hits

Sequencei

Sequence statusi: Complete.

A0A2K5UDH1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGEEQSTVSG GGGPQESQTL AGGTAGHPEP PRPQGDSARA PPLRAASAEP
60 70 80 90 100
SSGGCGSDWG CADTSAPEPA RSLGAPGWRK SRAPAQPAGL ALTGPLNPQT
110 120 130 140 150
LQLQLELEEE EEEAGDRKEG GDEQQEAPPG EELEPRTRAG AADGLVLDVL
160 170 180 190 200
GQRRPPLAKR QVFCSVYCVE SDLPEAPASE QLSPPASPPG APPVLNPPST
210 220 230 240 250
RSSFPSPRLS LPTDSLSPDG GSIELEFYLA PEPFSMPSLL GAPPYSGLGG
260 270 280 290 300
VGDPYAPLMV LMCRVCLEDK PIKPLPCCKK AVCEECLKVY LSAQVQLGQV
310 320 330 340 350
EIKCPITECF EFLEETTVVY NLTHEDSIKY KYFLELGRID SSTKPCPQCK
360 370 380 390 400
HFTTFKKKGH IPTPSRSESK YKIQCPTCQF VWCFKCHSPW HEGVNCKEYK
410 420 430 440 450
KGDKLLRHWA SEIEHGQRNA QKCPKCKIHI QRTEGCDHMT CSQCNTNFCY
460 470 480 490 500
RCGERYRQLR FFGDHTSNLS IFGCKYRYLP ERPHLRRLVR GSVCAGKLFI
510 520 530 540
APLIMVLGLA LGAIAVVIGL FVFPIYCLCK KQRKRSRTGM HW
Length:542
Mass (Da):59,400
Last modified:March 28, 2018 - v1
Checksum:iCE39D07F7439D435
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01049714 Genomic DNA No translation available.
AQIA01049715 Genomic DNA No translation available.
AQIA01049716 Genomic DNA No translation available.
AQIA01049717 Genomic DNA No translation available.
RefSeqiXP_005551777.1, XM_005551720.2

Genome annotation databases

EnsembliENSMFAT00000040404; ENSMFAP00000010402; ENSMFAG00000007187
GeneIDi102118830
KEGGimcf:102118830

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01049714 Genomic DNA No translation available.
AQIA01049715 Genomic DNA No translation available.
AQIA01049716 Genomic DNA No translation available.
AQIA01049717 Genomic DNA No translation available.
RefSeqiXP_005551777.1, XM_005551720.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMFAT00000040404; ENSMFAP00000010402; ENSMFAG00000007187
GeneIDi102118830
KEGGimcf:102118830

Organism-specific databases

CTDi154214

Phylogenomic databases

GeneTreeiENSGT00730000111285
KOiK11977

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR031127 E3_UB_ligase_RBR
IPR002867 IBR_dom
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR11685 PTHR11685, 1 hit
PfamiView protein in Pfam
PF01485 IBR, 2 hits
SMARTiView protein in SMART
SM00647 IBR, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K5UDH1_MACFA
AccessioniPrimary (citable) accession number: A0A2K5UDH1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: July 18, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again