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Protein

BMP and activin membrane-bound inhibitor homolog

Gene

BAMBI

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Negatively regulates TGF-beta signaling.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
BMP and activin membrane-bound inhibitor homologUniRule annotation
Gene namesi
Name:BAMBIImported
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei148 – 173HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501431838921 – 260BMP and activin membrane-bound inhibitor homologSequence analysisAdd BLAST240

Interactioni

GO - Molecular functioni

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili173 – 193Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the BAMBI family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000014168
KOiK10162

Family and domain databases

InterProiView protein in InterPro
IPR009345 BAMBI
PANTHERiPTHR15505:SF1 PTHR15505:SF1, 1 hit
PfamiView protein in Pfam
PF06211 BAMBI, 1 hit
PIRSFiPIRSF037456 BAMBI, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K5TQC0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRHSSYIFI WLQLELCAMA VLLTKGEIRC YCDAAHCVAT GYMCKSELSA
60 70 80 90 100
CFSRLLDPQN SNSPLTHGCL DSLASTADIC QAKQARNHSG TTMPTLECCH
110 120 130 140 150
EDMCNYRGLH DVLSPPKGEA SGQGNRYQHD GSRNLITKVQ ELTSSKELWF
160 170 180 190 200
RAAVIAVPIA GGLILVLLIM LALRMLRSEN KRLQDQRQQM LSRLHYSFHG
210 220 230 240 250
HHSKKGQVAK LDLECMVPVS GHENCCLTCD KMRQADLSND KILSLVHWGM
260
YSGHGKLEFV
Length:260
Mass (Da):29,068
Last modified:March 28, 2018 - v1
Checksum:iAC1C4935B29B0F4E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01070478 Genomic DNA No translation available.
RefSeqiXP_005564935.1, XM_005564878.2

Genome annotation databases

EnsembliENSMFAT00000027399; ENSMFAP00000002255; ENSMFAG00000037543
GeneIDi102119925
KEGGimcf:102119925

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01070478 Genomic DNA No translation available.
RefSeqiXP_005564935.1, XM_005564878.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMFAT00000027399; ENSMFAP00000002255; ENSMFAG00000037543
GeneIDi102119925
KEGGimcf:102119925

Organism-specific databases

CTDi25805

Phylogenomic databases

GeneTreeiENSGT00390000014168
KOiK10162

Family and domain databases

InterProiView protein in InterPro
IPR009345 BAMBI
PANTHERiPTHR15505:SF1 PTHR15505:SF1, 1 hit
PfamiView protein in Pfam
PF06211 BAMBI, 1 hit
PIRSFiPIRSF037456 BAMBI, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K5TQC0_MACFA
AccessioniPrimary (citable) accession number: A0A2K5TQC0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: September 12, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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