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Protein
Submitted name:

Polycystin 2, transient receptor potential cation channel

Gene

PKD2

Organism
Cebus capucinus imitator
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi765 – 776PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Polycystin 2, transient receptor potential cation channelImported
Gene namesi
Name:PKD2Imported
OrganismiCebus capucinus imitatorImported
Taxonomic identifieri1737458 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCebinaeCebus
Proteomesi
  • UP000233040 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei226 – 250HelicalSequence analysisAdd BLAST25
Transmembranei425 – 445HelicalSequence analysisAdd BLAST21
Transmembranei465 – 490HelicalSequence analysisAdd BLAST26
Transmembranei511 – 529HelicalSequence analysisAdd BLAST19
Transmembranei558 – 579HelicalSequence analysisAdd BLAST22
Transmembranei599 – 621HelicalSequence analysisAdd BLAST23
Transmembranei661 – 682HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini752 – 787EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili770 – 794Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00700000104221

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR013122 PKD1_2_channel
IPR003915 PKD_2
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF08016 PKD_channel, 1 hit
PRINTSiPR01433 POLYCYSTIN2
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K5RUG4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNSSRVQPQ QPGDAKQPPA PRAPGPGRLM AGGAAVGASL AARGGLREQR
60 70 80 90 100
GLEIEMQRIR QAAARDPPAG ASASPSPPLS SCSRQAWSRD NPGFEAEEEE
110 120 130 140 150
EEEEVEGEEG GMVVEMDVEW RPGSRRSAAS SAVSSAGALS RGLGGYHGAG
160 170 180 190 200
HPSGRRHRRE DQGPPCPSPT GGGDPLHRHL PLDGQPPRVA WAVRLVRGLR
210 220 230 240 250
GLWGTRLMEE SSTNREKYLK SVLRELVTYL LFLIVLCILT YGMMSSNVYY
260 270 280 290 300
YTRMMSQLFL DTPVSKTEKT NFKTLSSMED FWKFTEGSLL DGLYWKMQPS
310 320 330 340 350
NQTEADNRSF IFYENLLLGV PRIRQLRVRN GSCSIPQDLR DEIKECYDVY
360 370 380 390 400
SVSSEDRAPF GPRNGTAWIY TSEKDLNGSS HWGIIATYSG AGYYLDLSRT
410 420 430 440 450
REETAAQVAS LKKNVWLDRG TRATFIDFSV YNANINLFCV VRLLVEFPAT
460 470 480 490 500
GGVIPSWQFQ PLKLIRYVTT FDFFLAACEI IFCFFILYYV VEEILEIRIH
510 520 530 540 550
KLHYFRSFWN CLDVVIIVLS VVAIGINIYR TSNVEVLLQF LEDQNTFPNF
560 570 580 590 600
EHLAYWQIQF NNVAAVTVFF VWIKLFKFIN FNRTMSQLST TMSRCAKDLF
610 620 630 640 650
GFAIMFFIIF LAYAQLAYLV FGTQVDDFST FQECIFTQFR IILGDINFAE
660 670 680 690 700
IEEANRVLGP IYFTTFVFFM FFILLNMFLA IINDTYSEVK SDLAQQKAEM
710 720 730 740 750
ELSDLIRKGY HKALVKLKLK KNTVDDISES LRQGGGKLNF DELRQDLKGK
760 770 780 790 800
GHTDAEIEAI FTKYDQDGDQ ELTEHEHQQM RDDLEKERED LDLDHSSLPR
810 820 830 840 850
PMSSRSFPRS LDDSEEDDDE DSGHSSRRRG SISSGVSYEE FQVLVRRVDR
860 870 880 890 900
MEHSIGSIVS KIDAVIVKLE IMERAKLKRR EVLGRLLDGV AEDERLGRDG
910 920 930 940 950
EIHREQMERL VREELERWES DDAASQISHG LGTPVGLNGQ PRPRSSRPSS
960 970
SQSTEGMEDA GGNGSSNVHI
Length:970
Mass (Da):109,821
Last modified:March 28, 2018 - v1
Checksum:i81F391B6DB22780C
GO

Sequence databases

RefSeqiXP_017400606.1, XM_017545117.1

Genome annotation databases

EnsembliENSCCAT00000049514; ENSCCAP00000031760; ENSCCAG00000033897
GeneIDi108315670

Similar proteinsi

Entry informationi

Entry nameiA0A2K5RUG4_CEBCA
AccessioniPrimary (citable) accession number: A0A2K5RUG4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: July 18, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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