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Protein
Submitted name:

Eukaryotic translation initiation factor 2 alpha kinase 4

Gene

EIF2AK4

Organism
Cebus capucinus imitator
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei619ATPUniRule annotation1
Active sitei850Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi596 – 604ATPUniRule annotation9

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 2 alpha kinase 4Imported
Gene namesi
Name:EIF2AK4Imported
OrganismiCebus capucinus imitatorImported
Taxonomic identifieri1737458 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCebinaeCebus
Proteomesi
  • UP000233040 Componenti: Whole Genome Shotgun Assembly

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 137RWDInterPro annotationAdd BLAST113
Domaini286 – 539Protein kinaseInterPro annotationAdd BLAST254
Domaini590 – 1003Protein kinaseInterPro annotationAdd BLAST414

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili147 – 199Sequence analysisAdd BLAST53

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

GeneTreeiENSGT00530000062984

Family and domain databases

Gene3Di3.10.110.10, 1 hit
3.40.50.800, 1 hit
InterProiView protein in InterPro
IPR036621 Anticodon-bd_dom_sf
IPR016255 Gcn2
IPR024435 HisRS-related_dom
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR006575 RWD-domain
IPR008271 Ser/Thr_kinase_AS
IPR016135 UBQ-conjugating_enzyme/RWD
PfamiView protein in Pfam
PF12745 HGTP_anticodon2, 1 hit
PF00069 Pkinase, 3 hits
PF05773 RWD, 1 hit
PIRSFiPIRSF000660 Ser/Thr_PK_GCN2, 2 hits
SMARTiView protein in SMART
SM00591 RWD, 1 hit
SM00220 S_TKc, 2 hits
SUPFAMiSSF54495 SSF54495, 1 hit
SSF56112 SSF56112, 3 hits
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 2 hits
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50908 RWD, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K5PUX7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGGRGAPGR GRDEPPESYP QRQDHELQAL EAIYGEDFQD LRPDAYGPVK
60 70 80 90 100
EPPEINLVLY PQGLTGEEVY VKVDLRVKCP PTYPDVVPEI ELKNAKGLSN
110 120 130 140 150
ESVNLLKSCL EELAKKHCGE VMIFELAYHV QSFLSEHNKP PPKSFHEEML
160 170 180 190 200
ERRAQEEQQR LLEAKRKEEQ EQREILHEIQ RRKEEIKEEK KRKEMAKQER
210 220 230 240 250
LEIAGLSNQD HTSKKDPGGH KMAAILHGSS PDFVGNGKHR ANSSGRSRRE
260 270 280 290 300
RQYSVCNSED SPGSCEILYF YMGSPDQLMV HKGKCIGSDE QLGKLVYNAL
310 320 330 340 350
ETATGCFVLL YEWVLQWQKK MGPFLTSQEK EKIDKCKKQI QGTETEFNSL
360 370 380 390 400
VKLSHPNVVR YLAMNLKEQD DSIVVDILVE HISGVSLAAH LSHSGPIPVH
410 420 430 440 450
QLRRYTAQLL SGLDYLHSNS VVHKVLSASN VLVDAEGTVK ITDYSISKRL
460 470 480 490 500
ADICKEDVFE QTRVRFSDNA LPYKTGKKGD VWRLGLLLLS LSQGQECGEY
510 520 530 540 550
PVTIPSDLPA DFQDFLKKCV CLDDKERWSP QQLLKHSFIN PQPKMPLVEQ
560 570 580 590 600
SPEDSGGQDY VETVIPSNRL PSAAFFSETQ RQFSRYFIEF EELQLLGKGA
610 620 630 640 650
FGAVIKVQNK LDGCCYAVKR IPINPASRQF RRIKGEVTLL SRLHHENIVR
660 670 680 690 700
YYNAWIERHE RPAGPGTPPP GSGPLGKDER AARGQSTSDT DGLGSVEAAA
710 720 730 740 750
PPPILSSSVE WSTSGERSAS ARFPAASPGS SDDEDDDDDD DERNGVFSQS
760 770 780 790 800
FLPASDSESD IIFDNEDENS KSENQDEDCN EKNGCHESEP SVTTEAVHYL
810 820 830 840 850
YIQMEYCEKS TLRDTIDQGL YQDTVRLWRL FREILDGLAY IHEKGMIHRD
860 870 880 890 900
LKPVNIFLDS DDHVKIGDFG LATDHLAFSA DSKQDDQAGD LIKSDPSGHL
910 920 930 940 950
TGMVGTALYV SPEVQGSTKS AYNQKVDLFS LGIIFFEMSY HPMITASERI
960 970 980 990 1000
FVLNQLRDPT SPKFPEDFDD GEHTKQKSVI SWLLNHDPAK RPTATELLKS
1010 1020 1030 1040 1050
ELLPPPQMEE SELHEVLHHT LTNVDGKAYR TMMAQIFSQR ISPAIDYTYD
1060 1070 1080 1090 1100
SDILKGNFSI RTAKMQQHVC ETIIRIFKRH GAVQLCTPLL LPRNRQIYEH
1110 1120 1130 1140 1150
NEAALFMDHS GMLVMLPFDL RIPFARYVAR NNILNLKRYC IERVFRPRKL
1160 1170 1180 1190 1200
DRFHPKELLE CAFDIVTSTT NSFLPTAEII YTIYEIIQEF PALQERNYNI
1210 1220 1230 1240 1250
YLNHTMLLKA ILLHCGIPED KLSQVYIILY DAMTEKLTRR EVEAKFCNLS
1260 1270 1280 1290 1300
LSSNSLCRLY KFIEQKGDLQ DLMPTINSLI KQKTGIAQLV KYGLKDLEEV
1310 1320 1330 1340 1350
VGLLKKLGIK LQVLINLGLV YKVQQHNGII FQFVAFIKRR QRAVPEILAA
1360 1370 1380 1390 1400
GGRYDLLIPQ FRGPQALGPA PTAIGVSIAI DKISAAVLNM EERVTISSCD
1410 1420 1430 1440 1450
LLVVSVGQMS MSRAINLTQK LWTAGITAEI MYDWSQSQEE LQEYCRHHEI
1460 1470 1480 1490 1500
TYVALVSDKE GSHVKVKSFE KERQTEKRVL ETELVDYVLQ KLRTKVSDER
1510 1520 1530 1540 1550
SVREASDNLA VQNLKGSFSN ASGLFEIHGA AVVPIVSVLA PEKLSASTRR
1560 1570 1580 1590 1600
RYETQVQTRL QTSLANLHQK SSEIEILAVD LPKETILQFL SLEWDADEQA
1610 1620 1630 1640 1650
FNTTVKQLLS RLPKQRYLKL VCDEIYNIKV EKKVSVLFLY SYRDDYYRIL

F
Length:1,651
Mass (Da):187,281
Last modified:March 28, 2018 - v1
Checksum:i526451EA7386AF6B
GO

Sequence databases

RefSeqiXP_017386409.1, XM_017530920.1

Genome annotation databases

EnsembliENSCCAT00000024796; ENSCCAP00000007421; ENSCCAG00000021302
GeneIDi108306132

Similar proteinsi

Entry informationi

Entry nameiA0A2K5PUX7_CEBCA
AccessioniPrimary (citable) accession number: A0A2K5PUX7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: July 18, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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