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Protein
Submitted name:

Mannan binding lectin serine peptidase 2

Gene

MASP2

Organism
Cercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, ProteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Mannan binding lectin serine peptidase 2Imported
Gene namesi
Name:MASP2Imported
OrganismiCercocebus atys (Sooty mangabey) (Cercocebus torquatus atys)Imported
Taxonomic identifieri9531 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeCercocebus
Proteomesi
  • UP000233060 Componenti: Whole Genome Shotgun Assembly

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501445976216 – 686Sequence analysisAdd BLAST671

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi184 ↔ 211PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 137CUBInterPro annotationAdd BLAST127
Domaini184 – 296CUBInterPro annotationAdd BLAST113
Domaini298 – 363SushiInterPro annotationAdd BLAST66
Domaini364 – 432SushiInterPro annotationAdd BLAST69
Domaini445 – 684Peptidase S1InterPro annotationAdd BLAST240

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

EGF-like domainSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, SushiPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118890

Family and domain databases

CDDicd00033 CCP, 2 hits
cd00041 CUB, 2 hits
cd00190 Tryp_SPc, 1 hit
Gene3Di2.60.120.290, 2 hits
InterProiView protein in InterPro
IPR000859 CUB_dom
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR037571 MASP2
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR035914 Sperma_CUB_dom_sf
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom
IPR001254 Trypsin_dom
IPR033116 TRYPSIN_SER
PANTHERiPTHR24255:SF10 PTHR24255:SF10, 1 hit
PfamiView protein in Pfam
PF00431 CUB, 2 hits
PF07645 EGF_CA, 1 hit
PF00084 Sushi, 2 hits
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00032 CCP, 2 hits
SM00042 CUB, 2 hits
SM00181 EGF, 1 hit
SM00179 EGF_CA, 1 hit
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF49854 SSF49854, 2 hits
SSF50494 SSF50494, 1 hit
SSF57535 SSF57535, 2 hits
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 1 hit
PS01180 CUB, 2 hits
PS01186 EGF_2, 1 hit
PS01187 EGF_CA, 1 hit
PS50923 SUSHI, 2 hits
PS50240 TRYPSIN_DOM, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K5N2X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLLTLLGLL CGSVATPSGP KWPEPVFGRL ASPGFPGEYA NDQEWRWTLT
60 70 80 90 100
APPGYRLRLY FTHFDLELSH LCEYDFVKLS SGAKVLATLC GHESTDTERA
110 120 130 140 150
PGNDTFYSLG SSLDITFRSD YSNEKPFTGF EAFYAAEDID ECQVAPGEAP
160 170 180 190 200
ACDHHCHNHL GGFYCSCRVG YILHRNKRTC SALCSGQVFT QRSGELSSPE
210 220 230 240 250
YPQPYPKLSS CTYSIRLEEG FSVILDFVES FDVETHPETL CPYDFLKIQT
260 270 280 290 300
DSEEHGPFCG KTLPRRIETK SNTVTITFVT DESGDHTGWK IHYTSTAQPC
310 320 330 340 350
PYPMAPPNGH VSPVQAKYIL KDSFSIFCQP GYELLQGHLP LKSFAAVCQK
360 370 380 390 400
DGSWDQPMPS CSIVDCGPPD DLPSGRVEYI TGPEVTTYKA VIQYSCEETF
410 420 430 440 450
YTMKVNDGKY VCEADGLWTS SKGERSPPVC EPVCGLSART TGGRIYGGQK
460 470 480 490 500
AKPGDFPWQV LILGGSTAAG ALLYDNWVLT AAHAIYEQKH DASSLDIRLG
510 520 530 540 550
ALKRLSPHYT QAWAEAVFIH EGYTHDAGFD NDIALIKLNN KVVINSNITP
560 570 580 590 600
ICLPRKEAES FMRTDDIGTA SGWGLTQRGL LARNLMYVDI PIVDHQKCTA
610 620 630 640 650
AYEKPPYSGG SVTANMLCAG LESGGKDSCR GDSGGALVFL DNETQRWFVG
660 670 680
GIVSWGSMNC GEAGQYGVYT KVINYIPWIK NIISNF
Length:686
Mass (Da):75,540
Last modified:March 28, 2018 - v1
Checksum:i422FE019109767B6
GO

Sequence databases

RefSeqiXP_011904768.1, XM_012049378.1

Genome annotation databases

EnsembliENSCATT00000056118; ENSCATP00000031852; ENSCATG00000039032
GeneIDi105580873

Similar proteinsi

Entry informationi

Entry nameiA0A2K5N2X8_CERAT
AccessioniPrimary (citable) accession number: A0A2K5N2X8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: May 23, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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