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Entry version 7 (05 Jun 2019)
Sequence version 1 (28 Mar 2018)
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Protein
Submitted name:

Uncharacterized protein

Gene

LRRIQ1

Organism
Colobus angolensis palliatus (Peters' Angolan colobus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LRRIQ1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiColobus angolensis palliatus (Peters' Angolan colobus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri336983 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeColobinaeColobus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000233080 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Whole Genome Shotgun Assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni21 – 48DisorderedSequence analysisAdd BLAST28
Regioni321 – 368DisorderedSequence analysisAdd BLAST48

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili164 – 206Sequence analysisAdd BLAST43
Coiled coili211 – 231Sequence analysisAdd BLAST21
Coiled coili254 – 274Sequence analysisAdd BLAST21
Coiled coili568 – 588Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi21 – 41PolyampholyteSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162858

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00612 IQ, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00015 IQ, 3 hits
SM00369 LRR_TYP, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096 IQ, 3 hits
PS51450 LRR, 11 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2K5J594-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDDDDAKLKA EIEAELDKLS ISSLEKEDIE SDSKSETQSD DSDTDSVELP
60 70 80 90 100
ESVLHCINII KNRSKAVEEL ILQDLEDTDI LSRSYGAVSN NHMHLRTGLS
110 120 130 140 150
TEYEESSEQL IKILSEIEKE EFMRSKTNCA SPDFVPEPIP HDLPMDEHVL
160 170 180 190 200
PDDADINFGY CEVEEKCRQS FEAWQEKQKE LENKEKETLK AQRDREEKQF
210 220 230 240 250
QEEEEKRHCW MKQFKVEKKK LENIQKQEQD KMNDELYEEE KIWKEKFKQH
260 270 280 290 300
EEYIRNLHLQ MEEERTRFKD QQEKEKNCLL KQQNNAAVKI QAKYKAFVAY
310 320 330 340 350
QKYGPIIKEQ IESRKRKAQE WKEKEAKIRQ KEEENRKRLE EEQRIKEERK
360 370 380 390 400
KQKEEERKRR EKEYEDKKNI MKQKREQLII KENIRLREDA SQQLIISSAL
410 420 430 440 450
KKRGYNNKHL SLEDISNDKG DIAKNLVDEN LKKQEDVLLW LAEESNMKEN
460 470 480 490 500
IDRQTILKES IQVQLKESIS SQTILADFKM EEKNKNLAKK QCSEEWVKQE
510 520 530 540 550
RKSENVDNKT ELGDSGLKGN LKEQFPLQEL KSDAQKEEIM KHVINENMGP
560 570 580 590 600
KTQIILEHNQ EINEVKTKEA QKIIKDNQQK KIQKVEKEEI QEQNGLLYKD
610 620 630 640 650
KDTLIISMKQ KSLSLTSENS EDAGENVILR EKEIYSKVKE IEENPKDNAW
660 670 680 690 700
NSGIVIFNTT DTMINKEGKR NNQDYVLGRH APCEDLSDCN AESSMVSKEV
710 720 730 740 750
NSLKSEIRKI SEKCPENGPE PESMTCSVPE STLLYSIEEK RLAWIKSFKP
760 770 780 790 800
WLETFKQNQQ KKIVRRKRPV KCPANMTPAL DKLEILRCGP WDTLQQVTTV
810 820 830 840 850
TFQDLPGCVL STLAECTNLQ FLSLQRCGLT SLHSLSNCKK LKYIDAQENR
860 870 880 890 900
IEAIDCENLE NLCVVLLNKN QLTSLHGLDG CTNIQCLELS HNKITRIGKV
910 920 930 940 950
CHHLGTSASY LSLTQVWIPT GLYCNFLISH LHWNCGLESL KNLQQLILDH
960 970 980 990 1000
NQLISTKGLC DTPTVVYLDC SHNHLTDVEG IENCGLLQIL KLQGNYLSEL
1010 1020 1030 1040 1050
PSLENLVLLR ELHLDDNSIS TVEAFSSYWL PLLQNLTVSQ NSLTKIVPLF
1060 1070 1080 1090 1100
HFVSLEKLDV SHNCLSDLKS VMKWFDACYS LRELSLTGNP LLQETNWRDS
1110 1120 1130 1140 1150
LLKVLPDLRI LNGNMLNSDS KSHTEEHNQL ESAGFLALCQ SQIREFSLLT
1160 1170 1180 1190 1200
ENYITGKGDV FTLDTAENLC HYFKKLMILS TEYRHAHERG DVNITKKDES
1210 1220 1230 1240 1250
EAQKNHLAPT NSDSTLQNGV FYSCAHEDNP DSPDNPEKWM DSVSSHSPLS
1260 1270 1280 1290 1300
NFSTCENMER RHQEILVCQK KEDSKASSIP TIRIPLKEVE MTNSVLRNHQ
1310 1320 1330 1340 1350
NIEPSEKIMA AVVIQSYWRG YLMRRQIHFS TRLCTAATEG LPNSSIKNQT
1360 1370 1380 1390 1400
ILKKEKRENI VNIQKQREKA AVLIQAVWKG FILRKKLTAA LQAIKNEESD
1410 1420 1430 1440 1450
EEYREIDLED FTFDEAALEE EWLASDSTRF PSQTLLLSNQ LHWPKIPGNL
1460 1470 1480 1490 1500
KWDDTSFNLP SNPAQAWLCN DKENLSSSEH TQLSGRSENR TSSWTLESKT
1510 1520 1530 1540 1550
SRKSLLKSEK EKKISEEWGF KDISTAQQML KRAQKMQSKK LKKKIDSTVR
1560 1570 1580 1590 1600
LSLFKNNENK VSVPKSSKKV QPRRDGYFEG IEEDPIHKDT TANEKLERNR
1610 1620 1630 1640 1650
EYTYQWLHTQ VEVHGTTSSR NMKCNHFLPE LDPDVLNGGR VQLVARRVSR
1660 1670 1680 1690
EDTDLDLLSM TSGSALSVKR GKKNQAHRHS AGSSSKLWFP SKLI
Length:1,694
Mass (Da):196,166
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9149F883FD622CE5
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSCANT00000046961; ENSCANP00000023967; ENSCANG00000035384

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCANT00000046961; ENSCANP00000023967; ENSCANG00000035384

Phylogenomic databases

GeneTreeiENSGT00940000162858

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00612 IQ, 2 hits
SMARTiView protein in SMART
SM00015 IQ, 3 hits
SM00369 LRR_TYP, 4 hits
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 3 hits
PS51450 LRR, 11 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2K5J594_COLAP
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2K5J594
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: June 5, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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