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Protein
Submitted name:

Uncharacterized protein

Gene

NGFR

Organism
Colobus angolensis palliatus (Peters' Angolan colobus)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:NGFRImported
OrganismiColobus angolensis palliatus (Peters' Angolan colobus)Imported
Taxonomic identifieri336983 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeColobinaeColobus
Proteomesi
  • UP000233080 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei252 – 272HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501443693229 – 427Sequence analysisAdd BLAST399

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi44 ↔ 57PROSITE-ProRule annotation
Disulfide bondi86 ↔ 99PROSITE-ProRule annotation
Disulfide bondi89 ↔ 107PROSITE-ProRule annotation
Disulfide bondi125 ↔ 138PROSITE-ProRule annotation
Disulfide bondi128 ↔ 146PROSITE-ProRule annotation
Disulfide bondi149 ↔ 164PROSITE-ProRule annotation
Disulfide bondi167 ↔ 180PROSITE-ProRule annotation
Disulfide bondi170 ↔ 188PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 64TNFR-CysInterPro annotationAdd BLAST34
Repeati31 – 64TNFR-CysPROSITE-ProRule annotationAdd BLAST34
Domaini66 – 107TNFR-CysInterPro annotationAdd BLAST42
Repeati66 – 107TNFR-CysPROSITE-ProRule annotationAdd BLAST42
Domaini108 – 146TNFR-CysInterPro annotationAdd BLAST39
Repeati108 – 146TNFR-CysPROSITE-ProRule annotationAdd BLAST39
Domaini148 – 188TNFR-CysInterPro annotationAdd BLAST41
Repeati148 – 188TNFR-CysPROSITE-ProRule annotationAdd BLAST41
Domaini344 – 421DeathInterPro annotationAdd BLAST78

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00730000110974

Family and domain databases

CDDicd13416 TNFRSF16, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR022325 TNFR_16
IPR034046 TNFRSF16_N
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF00020 TNFR_c6, 2 hits
PRINTSiPR01966 TNFACTORR16
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SM00208 TNFR, 4 hits
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit
PS00652 TNFR_NGFR_1, 2 hits
PS50050 TNFR_NGFR_2, 4 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2K5IID8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRAGATGRAM DGPRLLLLLL LGVSLGGAKE ACPTGLYTHS GECCKACNLG
60 70 80 90 100
EGVAQPCGAN QTVCEPCLDS VTFSDVVSAT EPCKPCTECV GLQSMSAPCV
110 120 130 140 150
EADDAVCRCA YGYYQDETTG RCEACRVCEA GSGLVFSCQD KQNTVCEECP
160 170 180 190 200
DGTYSDEANH VDPCLPCTVC EDTERQLREC TRWADAECEE IPGRWITRST
210 220 230 240 250
PPEGSDSTAP STQEPEAPPE QDLIASTVAD VVTTVMGSSQ PVVTRGTTDN
260 270 280 290 300
LIPVYCSILA AVVVGLVAYI AFKRWNSCKQ NKQGANSRPV NQTPPPEGEK
310 320 330 340 350
LHSDSGISVD SQSLHDQQPH TQTASGQALK GDGGLYSSLP PAKREEVEKL
360 370 380 390 400
LNGSAGDTWR HLAGELGYQP EHIDSFTHEA CPVRALLASW ATQDSATLDA
410 420
LLAALRRIQR ADLVESLCSE STATSPV
Length:427
Mass (Da):45,341
Last modified:March 28, 2018 - v1
Checksum:i4FCD201E3A3E1135
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K5IHT5A0A2K5IHT5_COLAP
Uncharacterized protein
NGFR
333Annotation score:

Sequence databases

RefSeqiXP_011815307.1, XM_011959917.1

Genome annotation databases

EnsembliENSCANT00000039168; ENSCANP00000016232; ENSCANG00000031550
GeneIDi105524594

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_011815307.1, XM_011959917.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCANT00000039168; ENSCANP00000016232; ENSCANG00000031550
GeneIDi105524594

Organism-specific databases

CTDi4804

Phylogenomic databases

GeneTreeiENSGT00730000110974

Family and domain databases

CDDicd13416 TNFRSF16, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR022325 TNFR_16
IPR034046 TNFRSF16_N
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF00020 TNFR_c6, 2 hits
PRINTSiPR01966 TNFACTORR16
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SM00208 TNFR, 4 hits
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit
PS00652 TNFR_NGFR_1, 2 hits
PS50050 TNFR_NGFR_2, 4 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K5IID8_COLAP
AccessioniPrimary (citable) accession number: A0A2K5IID8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: October 10, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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