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Protein
Submitted name:

Myosin heavy chain 6

Gene

MYH6

Organism
Aotus nancymaae (Ma's night monkey)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi177 – 184ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotationSAAS annotation, Motor protein, MyosinPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Myosin heavy chain 6Imported
Gene namesi
Name:MYH6Imported
OrganismiAotus nancymaae (Ma's night monkey)Imported
Taxonomic identifieri37293 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniAotidaeAotus
Proteomesi
  • UP000233020 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 81Myosin N-terminal SH3-likeInterPro annotationAdd BLAST50
Domaini85 – 787Myosin motorInterPro annotationAdd BLAST703

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni664 – 686Actin-bindingPROSITE-ProRule annotationAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili858 – 1165Sequence analysisAdd BLAST308
Coiled coili1173 – 1193Sequence analysisAdd BLAST21
Coiled coili1202 – 1243Sequence analysisAdd BLAST42
Coiled coili1247 – 1383Sequence analysisAdd BLAST137
Coiled coili1385 – 1447Sequence analysisAdd BLAST63
Coiled coili1462 – 1605Sequence analysisAdd BLAST144
Coiled coili1617 – 1721Sequence analysisAdd BLAST105
Coiled coili1729 – 1812Sequence analysisAdd BLAST84
Coiled coili1814 – 1841Sequence analysisAdd BLAST28
Coiled coili1870 – 1932Sequence analysisAdd BLAST63

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118919

Family and domain databases

Gene3Di2.30.30.360, 1 hit
3.40.850.10, 3 hits
4.10.270.10, 1 hit
InterProiView protein in InterPro
IPR000048 IQ_motif_EF-hand-BS
IPR036961 Kinesin_motor_dom_sf
IPR001609 Myosin_head_motor_dom
IPR027401 Myosin_IQ_contain_sf
IPR004009 Myosin_N
IPR008989 Myosin_S1_N
IPR002928 Myosin_tail
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00063 Myosin_head, 1 hit
PF02736 Myosin_N, 1 hit
PF01576 Myosin_tail_1, 1 hit
PRINTSiPR00193 MYOSINHEAVY
SMARTiView protein in SMART
SM00242 MYSc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50096 IQ, 1 hit
PS51456 MYOSIN_MOTOR, 1 hit
PS51844 SH3_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K5EW03-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDAQMADFG AAAQYLRKSE KERLEAQTRP FDIRTECFVP DDKEEFVKAK
60 70 80 90 100
IVSREGGKVT AETENGKTVT VKEDQVLQQN PPKFDKIEDM AMLTFLHEPA
110 120 130 140 150
VLFNLKERYA AWMIYTYSGL FCVTVNPYKW LPVYNAEVVA AYRGKKRSEA
160 170 180 190 200
PPHIFSISDN AYQYMLTGEP GDSWPLGESG AGKTVNTKRV IQYFASIAAI
210 220 230 240 250
GDRGKKDNAN ANKGTLEDQI IQANPALEAF GNAKTVRNDN SSRFGKFIRI
260 270 280 290 300
HFGATGKLAS ADIETCYRPP GPLYLLEKSR VIFQLKAERN YHIFYQILSN
310 320 330 340 350
KKPELLDMLL VTNNPYDYAF VSQGEVSVAS IDDSEELMAT DSAFDVLGFT
360 370 380 390 400
SEEKAGVYKL TGAIMHYGNM KFKQKQREEQ AEPDGTEDAD KSAYLMGLNS
410 420 430 440 450
ADLLKGLCHP RVKVGNEYVT KGQSVQQVYY SIGALAKAVY EKMFNWMVTR
460 470 480 490 500
INATLETKQP RQYFIGVLDI AGFEIFDFNS FEQLCINFTN EKLQQFFNHH
510 520 530 540 550
MFVLEQEEYK KEGIEWEFID FGMDLQACID LIEKPMGIMS ILEEECMFPK
560 570 580 590 600
ATDMTFKAKL YDNHLGKSNN FQKPRNIKGK PEAHFSLIHY AGTVDYNILG
610 620 630 640 650
WLEKNKDPLN ETVVALYQKS SLKLMATLFS TYASADSGDS GKSKGGKKKG
660 670 680 690 700
SSFQTVSALH RENLNKLMTN LRTTHPHFVR CIIPNERKAP GVMDNPLVMH
710 720 730 740 750
QLRCNGVLEG IRICRKGFPN RILYGDFRQR YRILNPAAIP EGQFIDSRKG
760 770 780 790 800
SEKLLSSLDI DHNQYKFGHT KVFFKAGLLG LLEEMRDERL SRILTRMQAQ
810 820 830 840 850
ARGQLMRIEF KKIVERRDAL LVIQWNIRAF MGVKNWPWMK LYFKIKPLLK
860 870 880 890 900
SAETEKEMAT MKEEFGRIKE TLEKSEARRK ELEEKMVSLL QEKNDLQLQV
910 920 930 940 950
QAEQDNLNDA EERCDQLIKN KIQLEAKVKE MNERLEDEEE MNAELTAKKR
960 970 980 990 1000
KLEDECSELK KDIDDLELTL AKVEKEKHAT ENKVKNLTEE MAGLDEIIAK
1010 1020 1030 1040 1050
LTKEKKALQE AHQQALDDLQ AEEDKVNSLS KSKVKLEQQV DDLEGSLEQE
1060 1070 1080 1090 1100
KKVRMDLERA KRKLEGDLKL TQESIMDLEN DKLQLDEKLK KKEFDINQLN
1110 1120 1130 1140 1150
SKIEDEQALA LQLQKKLKEN QARIEELEEE LEAERTARAK VEKLRSDLSR
1160 1170 1180 1190 1200
ELEEISERLE EAGGATSVQI EMNKKREAEF QKMRRDLEEA TLQHEATAAA
1210 1220 1230 1240 1250
LRKKHADSVA ELGEQIDNLQ RVKQKLEKEK SEFKLELDDV TSNMEHIIKA
1260 1270 1280 1290 1300
KANLEKVSRT LEDQANEYRV KLEEAQRSLN DFTTQRAKLQ TENGELARQL
1310 1320 1330 1340 1350
EEKEALISQL TRGKLSYTQQ MEDLKRQLEE EGKAKNALAH ALQSARHDCD
1360 1370 1380 1390 1400
LLREQYEEET EAKAELQRVL SKANSEVAQW RTKYETDAIQ RTEELEEAKK
1410 1420 1430 1440 1450
KLAQRLQDAE EAVEAVNAKC SSLEKTKHRL QNEIEDLMVD VERSNAAAAA
1460 1470 1480 1490 1500
LDKKQRNFDK ILAEWKQKYE ESQSELESSQ KEARSLSTEL FKLKNAYEES
1510 1520 1530 1540 1550
LEHLETFKRE NKNLQEEISD LTEQLGEGGK NVHELEKVRK QLEVEKLELQ
1560 1570 1580 1590 1600
SALEEAEASL EHEEGKILRA QLEFNQIKAE IERKLAEKDE EMEQAKRNHQ
1610 1620 1630 1640 1650
RVVDSLQTSL DAETRSRNEA LRVKKKMEGD LNEMEIQLSH ANRMAAEAQK
1660 1670 1680 1690 1700
QVKSLQSLLK DTQIQLDDAV RANDDLKENI AIVERRNNLL QAELEELRAV
1710 1720 1730 1740 1750
VEQTERSRKL AEQELIETSE RVQLLHSQNT SLINQKKKME SDLTQLQSEV
1760 1770 1780 1790 1800
EEAVQECRNA EEKAKKAITD AAMMAEELKK EQDTSAHLER MKKNMEQTIK
1810 1820 1830 1840 1850
DLQHRLDEAE QIALKGGKKQ LQKLEARVRE LEGELEAEQK RNAESVKGMR
1860 1870 1880 1890 1900
KSERRIKELT YQTEEDKKNL LRLQDLVDKL QLKVKAYKRQ AEEAEEQANT
1910 1920 1930 1940
NLSKFRKVQH ELDEAEERAD IAESQVNKLR AKSRDIGAKQ KMHDEE
Length:1,946
Mass (Da):224,198
Last modified:March 28, 2018 - v1
Checksum:iA672170E7A827181
GO

Genome annotation databases

EnsembliENSANAT00000055496; ENSANAP00000037414; ENSANAG00000036061

Similar proteinsi

Entry informationi

Entry nameiA0A2K5EW03_AOTNA
AccessioniPrimary (citable) accession number: A0A2K5EW03
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: June 20, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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