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Entry version 3 (23 May 2018)
Sequence version 1 (28 Mar 2018)
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Protein
Submitted name:

COL1A1 isoform 4

Gene

CR201_G0012259

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
COL1A1 isoform 4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CR201_G0012259Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9601 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini41 – 99VWFCInterPro annotationAdd BLAST59
Domaini1232 – 1467Fibrillar collagen NC1InterPro annotationAdd BLAST236

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008160 Collagen
IPR000885 Fib_collagen_C
IPR001007 VWF_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 15 hits
PF00093 VWC, 1 hit

ProDom; a protein domain database

More...
ProDomi
View protein in ProDom or Entries sharing at least one domain
PD002078 Fib_collagen_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00038 COLFI, 1 hit
SM00214 VWC, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51461 NC1_FIB, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2J8W8U1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRSRRAFKDL RKEERGEGRE VKNPITTDNA PLLPPVPVPP ITCVQNGLRY
60 70 80 90 100
HDRDVWKPEP CRICVCDNGK VLCDDVICDE TKNCPGAEVP EGECCPVCPD
110 120 130 140 150
GSESPTDQET TGVEGPKGDT GPRGPRGPAG PPGRDGIPGQ PGLPGPPGPP
160 170 180 190 200
GPPGPPGLGG NFAPQLSYGY DEKSTGGISV PGPMGPSGPR GLPGPPGAPG
210 220 230 240 250
PQGFQGPPGE PGEPGASGPM GPRGPPGPPG KNGDDGEAGK PGRPGERGPP
260 270 280 290 300
GPQGARGLPG TAGLPGMKGH RGFSGLDGAK GDAGPAGPKG EPGSPGENGA
310 320 330 340 350
PGQMGPRGLP GERGRPGAPG PAGARGNDGA TGAAGPPGPT GPAGPPGFPG
360 370 380 390 400
AVGAKGEAGP QGPRGSEGPQ GVRGEPGPPG PAGAAGPAGN PGADGQPGAK
410 420 430 440 450
GANGAPGIAG APGFPGARGP SGPQGPGGPP GPKGNSGEPG APGSKGDTGA
460 470 480 490 500
KGEPGPVGVQ GPPGPAGEEG KRGARGEPGP TGLPGPPGER GGPGSRGFPG
510 520 530 540 550
ADGVAGPKGP AGERGSPGPA GPKGSPGEAG RPGEAGLPGA KGLTGSPGSP
560 570 580 590 600
GPDGKTGPPG PAGQDGRPGP PGPPGARGQA GVMGFPGPKG AAGEPGKAGE
610 620 630 640 650
RGVPGPPGAV GPAGKDGEAG AQGPPGPAGP AGERGEQGPA GSPGFQGLPG
660 670 680 690 700
PAGPPGEAGK PGEQGVPGDL GAPGPSGARG ERGFPGERGV QGPPGPAGPR
710 720 730 740 750
GANGAPGNDG AKGDAGAPGA PGSQGAPGLQ GMPGERGAAG LPGPKGDRGD
760 770 780 790 800
AGPKGADGSP GKDGVRGLTG PIGPPGPAGA PGDKGETGPS GPAGPTGARG
810 820 830 840 850
APGDRGEPGP PGPAGFAGPP GADGQPGAKG EPGDAGAKGD AGPPGPAGPA
860 870 880 890 900
GPPGPIGNVG APGAKGARGS AGPPGATGFP GAAGRVGPPG PSGNAGPPGP
910 920 930 940 950
PGPAGKEGGK GPRGETGPAG RPGEVGPPGP PGPAGEKGSP GADGPAGAPG
960 970 980 990 1000
TPGPQGIAGQ RGVVGLPGQR GERGFPGLPG PSGEPGKQGP SGASGERGPP
1010 1020 1030 1040 1050
GPMGPPGLAG PPGESGREGA PGAEGSPGRD GSPGAKGDRG ETGPAGPPGA
1060 1070 1080 1090 1100
PGAPGAPGPV GPAGKSGDRG ETGPAGPAGP VGPVGARGPA GPQGPRGDKG
1110 1120 1130 1140 1150
ETGEQGDRGI KGHRGFSGLQ GPPGPPGSPG EQGPSGASGP AGPRGPPGSA
1160 1170 1180 1190 1200
GAPGKDGLNG LPGPIGPPGP RGRTGDAGPV GPPGPPGPPG PPGPPSGGFD
1210 1220 1230 1240 1250
FSFLPQPPQE KAHDGGRYYR ADDANVVRDR DLEVDTTLKS LSQQIENIRS
1260 1270 1280 1290 1300
PEGSRKNPAR TCRDLKMCHS DWKSGEYWID PNQGCNLDAI KVFCNMETGE
1310 1320 1330 1340 1350
TCVYPTQPSV AQKNWYISKN PKDKRHVWFG ESMTDGFQFE YGGQGSDPAD
1360 1370 1380 1390 1400
VAIQLTFLRL MSTEASQNIT YHCKNSVAYM DQQTGNLKKA LLLQGSNEIE
1410 1420 1430 1440 1450
IRAEGNSRFT YSVTVDGCTS HTGAWGKTVI EYKTTKTSRL PIIDVAPLDV
1460
GAPDQEFGFD VGPVCFL
Length:1,467
Mass (Da):139,412
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE937F7BBC8C136F0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
NDHI03003397 Genomic DNA Translation: PNJ66159.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NDHI03003397 Genomic DNA Translation: PNJ66159.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR008160 Collagen
IPR000885 Fib_collagen_C
IPR001007 VWF_dom
PfamiView protein in Pfam
PF01410 COLFI, 1 hit
PF01391 Collagen, 15 hits
PF00093 VWC, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002078 Fib_collagen_C, 1 hit
SMARTiView protein in SMART
SM00038 COLFI, 1 hit
SM00214 VWC, 1 hit
PROSITEiView protein in PROSITE
PS51461 NC1_FIB, 1 hit
PS01208 VWFC_1, 1 hit
PS50184 VWFC_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2J8W8U1_PONAB
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2J8W8U1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: May 23, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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