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Entry version 8 (05 Jun 2019)
Sequence version 1 (28 Mar 2018)
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Protein
Submitted name:

CELSR1 isoform 1

Gene

CR201_G0031785

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer
LigandCalciumSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
CELSR1 isoform 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CR201_G0031785Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9601 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2469 – 2492HelicalSequence analysisAdd BLAST24
Transmembranei2504 – 2522HelicalSequence analysisAdd BLAST19
Transmembranei2528 – 2550HelicalSequence analysisAdd BLAST23
Transmembranei2571 – 2591HelicalSequence analysisAdd BLAST21
Transmembranei2611 – 2631HelicalSequence analysisAdd BLAST21
Transmembranei2652 – 2674HelicalSequence analysisAdd BLAST23
Transmembranei2680 – 2703HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501447152625 – 3013Sequence analysisAdd BLAST2989

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi1350 ↔ 1359PROSITE-ProRule annotation
Disulfide bondi1388 ↔ 1397PROSITE-ProRule annotation
Disulfide bondi1674 ↔ 1683PROSITE-ProRule annotation
Disulfide bondi1897 ↔ 1906PROSITE-ProRule annotation
Disulfide bondi1935 ↔ 1944PROSITE-ProRule annotation
Disulfide bondi2002 ↔ 2014PROSITE-ProRule annotation
Disulfide bondi2004 ↔ 2021PROSITE-ProRule annotation
Disulfide bondi2023 ↔ 2032PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1302 – 1360EGF-likeInterPro annotationAdd BLAST59
Domaini1362 – 1398EGF-likeInterPro annotationAdd BLAST37
Domaini1402 – 1440EGF-likeInterPro annotationAdd BLAST39
Domaini1441 – 1645LAM_G_DOMAINInterPro annotationAdd BLAST205
Domaini1648 – 1684EGF-likeInterPro annotationAdd BLAST37
Domaini1688 – 1869LAM_G_DOMAINInterPro annotationAdd BLAST182
Domaini1871 – 1907EGF-likeInterPro annotationAdd BLAST37
Domaini1908 – 1945EGF-likeInterPro annotationAdd BLAST38
Domaini2002 – 2049Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini2034 – 2107G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST74
Domaini2407 – 2459GPSInterPro annotationAdd BLAST53
Domaini2467 – 2704G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST238

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni203 – 241DisorderedSequence analysisAdd BLAST39
Regioni2289 – 2327DisorderedSequence analysisAdd BLAST39
Regioni2773 – 2939DisorderedSequence analysisAdd BLAST167
Regioni2951 – 3013DisorderedSequence analysisAdd BLAST63

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2811 – 2827PolarSequence analysisAdd BLAST17
Compositional biasi2828 – 2843PolyampholyteSequence analysisAdd BLAST16
Compositional biasi2871 – 2902PolyampholyteSequence analysisAdd BLAST32
Compositional biasi2958 – 2974PolarSequence analysisAdd BLAST17

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, Laminin EGF-like domainPROSITE-ProRule annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.1240.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR013320 ConA-like_dom_sf
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR032471 GAIN_dom_N
IPR017981 GPCR_2-like
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR000832 GPCR_2_secretin-like
IPR000203 GPS
IPR009030 Growth_fac_rcpt_cys_sf
IPR002049 Laminin_EGF
IPR001791 Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00002 7tm_2, 1 hit
PF00028 Cadherin, 8 hits
PF00008 EGF, 2 hits
PF16489 GAIN, 1 hit
PF01825 GPS, 1 hit
PF00053 Laminin_EGF, 1 hit
PF02210 Laminin_G_2, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00205 CADHERIN
PR00249 GPCRSECRETIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00112 CA, 9 hits
SM00181 EGF, 6 hits
SM00179 EGF_CA, 4 hits
SM00180 EGF_Lam, 1 hit
SM00303 GPS, 1 hit
SM00008 HormR, 1 hit
SM00282 LamG, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49313 SSF49313, 9 hits
SSF49899 SSF49899, 2 hits
SSF57184 SSF57184, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010 ASX_HYDROXYL, 2 hits
PS00232 CADHERIN_1, 6 hits
PS00022 EGF_1, 5 hits
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 6 hits
PS01248 EGF_LAM_1, 1 hit
PS50027 EGF_LAM_2, 1 hit
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS50025 LAM_G_DOMAIN, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2J8TW31-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPPPPVLPV LLLLAAATAL PAMGLRAAAW EPRVPGGTRA FALGPGCTYA
60 70 80 90 100
VGAARTPRAP RELLDVGRDG RLAGRRRISG AGSPLPLQVL LAARGAPTAL
110 120 130 140 150
SRRLRARAHH PGCGARAWLC GTGARLCGAL RFPVPGGCAP AQHSALAAPT
160 170 180 190 200
ALPACRCPPR PGPRCPGRPI CLPPGSSVCL RLLCALRRAA GVVRVGLSLE
210 220 230 240 250
AATAGTPSAS PSPSPTLPPN LPEARAGPAR RARRGTSGRG SLKFPMPNYQ
260 270 280 290 300
VALFENEPAG TLILQLHAHY TIEGEEERVS YYMEGLFDER SRGYFRIDSA
310 320 330 340 350
TGAVSTDSVL DRETKETHVL RVKAVDYSTP PRSATTYITV LVKDTNDHSP
360 370 380 390 400
VFEQSEYRER VRENLEVGYE VLTIRASDRD SPINANLRYR VLGGAWDVFQ
410 420 430 440 450
LNESSGVVST RAVLDREEAA EYQLLVEAND QGRNPGPLSA TATVYIEVED
460 470 480 490 500
ENDNYPQFSE QNYVVQVPED VGLNTAVLRV QATDRDQGQN AAIHYSILSG
510 520 530 540 550
NVAGQFYLHS LSGILDVINP LDFEDVQKYS LSIKAQDGGR PPLINSSGVV
560 570 580 590 600
SVQVLDVNDN EPIFVSSPFQ ATVLENVPLG YPVVHIQAVD ADSGENARLH
610 620 630 640 650
YRLVNTASAF LGGGSAGPKN PAPTPDFPFQ IHNSSGWITV CAELDREEVE
660 670 680 690 700
HYSFGVEAVD HGSPPMSSST SVSITVLDVN DNDPVFTQPT YELRLNEDAA
710 720 730 740 750
VGSSVLTLQA RDRDANSVIT YQLTGGNTRN RFALSSQRGG GLITLALPLD
760 770 780 790 800
YKQEQQYVLA VTASDGTRSH TAHVLINITD ANTHRPVFQS SHYTVSVSED
810 820 830 840 850
RPVGTSIATL SANDEDTGEN ARITYVIQDP VPQFRIDPDS GTMYTMMELD
860 870 880 890 900
YENQVAYTLT IMAQDNGIPQ KSDTTTLEIL ILDANDNAPQ FLWDFYQGSI
910 920 930 940 950
FEDAPPSTSI LQVSAMDRDS GPNGRLLYTF QGGDDGDGDF YIEPTSGVIR
960 970 980 990 1000
TQRRLDRENV AVYNLWALAV DRGSPTPLSA SVEIQVTILD INDNAPMFEK
1010 1020 1030 1040 1050
DELELFVEEN NPVGSVVAKI RANDPDEGPN AQIMYQIVEG DMRHFFQLDL
1060 1070 1080 1090 1100
LNGDLRAMVE LDFEVRREYV LVVQATSAPL VSRATVHILL VDQNDNPPVL
1110 1120 1130 1140 1150
PDFQILFNNY VTNKSNSFPT GVIGRIPAHD PDVSDSLNYT FVQGNELRLL
1160 1170 1180 1190 1200
LLDPATGELQ LSRDLDNNRP LEALMEVSVS DGIHSVTAFC TLRVTIITDD
1210 1220 1230 1240 1250
MLTNSITVRL ENMSQEKFLS PLLALFVEGV AAVLSTTKDD VFVFNVQNDT
1260 1270 1280 1290 1300
DVSSNILNVT FSALLPGGVR GQFFPSEDLQ EQIYLNRTLL TTISTQRVLP
1310 1320 1330 1340 1350
FDDNICLREP CENYMKCVSV LRFDSSAPFL SSTTVLFRPI HPINGLRCRC
1360 1370 1380 1390 1400
PPGFTGDYCE TEIDLCYSNP CGANGRCRSR EGGYTCECFE DFTGEHCEVD
1410 1420 1430 1440 1450
ARSGRCANGV CKNGGTCVNL LIGGFHCVCP PGEYERPYCE VTTRSFPPRS
1460 1470 1480 1490 1500
FVTFRGLRQR FHFTISLTFA TQERNGLLLY NGRFNEKHDF IALEIVDEQV
1510 1520 1530 1540 1550
QLTFSAGETT TTVAPKVPSG VSDGRWHSVQ VQYYNKPNIG HLGLPHGPSG
1560 1570 1580 1590 1600
EKMAVVTVDD CDTTMAVRFG RDIGNYSCAA QGTQTGSKKS LDLTGPLLLG
1610 1620 1630 1640 1650
GVPNLPEDFP VHNRQFVGCM RNLSVDGKNV DMAGFIANNG TQEGCAARRN
1660 1670 1680 1690 1700
FCDGRRCQNG GTCVNRWNMY LCECPLRFGG KNCEQAMPHP QLFSGESVVS
1710 1720 1730 1740 1750
WSDLNVIISV PWYLGLMFRT RKEDSVLMEA TSGGPTSFRL QILNNYLQFE
1760 1770 1780 1790 1800
VSHGPSDVES VMLSRVRVTD GEWHHLLIEL KNVKEDSEMK HLVSMSLDYG
1810 1820 1830 1840 1850
MDQNRADIGG MLPGLTIRSM VVGGASEDKV SVRRGFRGCM QGVRMGGTPT
1860 1870 1880 1890 1900
NVATLNMNNA LKVRVKDGCD VEDPCTSSPC PPNSHCHDAW EDYSCVCDKG
1910 1920 1930 1940 1950
YLGVNCVDAC HLNPCENMGA CVRSPSSPQG YVCECGPSHY GPYCENKLDL
1960 1970 1980 1990 2000
PCPRGWWGNP VCGPCHCAVS KGFDPDCNKT NGQCQCKENY YKPPAQDTCL
2010 2020 2030 2040 2050
PCDCFPHGSH SRTCDMATGQ CACKPGVIGR QCNRCDNPFA EVTTLGCEVI
2060 2070 2080 2090 2100
YNGCPKAFEA GIWWPQTKFG QPAAVPCPKG SVGNAVRHCS GEKGWLPPEL
2110 2120 2130 2140 2150
FNCTTTSFLD LRAMNEKLSR NETQVDGAGA LRLVRALRNA TRHTGMLFGN
2160 2170 2180 2190 2200
DVRTAYQLLG HVLQHESWQQ GFDLAATQDA DFHEDVIHSG SALLAPATRA
2210 2220 2230 2240 2250
AWEQIQRSEG GTAQLLRRLE GYFSNVARNV RRTYLRPFVI VTANMILAVD
2260 2270 2280 2290 2300
IFDKFNFTGA RVPRFDAIHE EFPRELESSV SFPADFFKPP EEKEGPLLRP
2310 2320 2330 2340 2350
AGRRTTPQTT RSGPGTEREA PISRRRRHPD DAGRFAVALV IIYRTLGQLL
2360 2370 2380 2390 2400
PERYDPDRRS LRLPHRPIIN TPMVSTLVYS EGAPLPRPLE RPILVEFALL
2410 2420 2430 2440 2450
EVEERTKPVC VFWNHSLALG GTGGWSARGC ELLSRNQTHV ACQCSHTASF
2460 2470 2480 2490 2500
AVLMDISRRE NGEVLPLKIV TYAAVSLSLA ALLVAFVLLS LVRTLRSNLH
2510 2520 2530 2540 2550
SIHKHLAAAL FLSQLVFVIG INQTENPFLC TVVAILLHYI YMSTFAWTLV
2560 2570 2580 2590 2600
ESLHVYRMLT EVRNIDTGPM RFYYVVGWGI PAIVTGLAVG LDPQGYGNPD
2610 2620 2630 2640 2650
FCWLSLQDTL IWSFAGPIGA VIIINTVTSV LSAKVSCQRK HHYYGKKGIV
2660 2670 2680 2690 2700
SLLRTAFLLL LLISATWLLG LLAVNRDALS FHYLFAIFSG LQGPFVLLFH
2710 2720 2730 2740 2750
CVLNQEVRKH LKGVLGGRKL HLEDSAATRA TLLTRSLNCN TTFGDGPDML
2760 2770 2780 2790 2800
RTDLGESTAS LDSTVRDEGI QKLSVSSGLV RGGHGEPDAS LMPRSSKDPP
2810 2820 2830 2840 2850
GHDSDSDSEL SLDEQSSSYA SSHSSDSEDD GVGAEEKWDP ARGAVHSTPK
2860 2870 2880 2890 2900
GDAVANHVPA GWPDQSLAES DSEDPSGKPR LKVETKVSVE LHREEQGSHR
2910 2920 2930 2940 2950
GDYPPDQESG GTARLASSQP PEQRKGILKN KVTYPPPLTL TEQTLKGRLR
2960 2970 2980 2990 3000
EKLADCEQSP TSSRTSSLGS GGPDCSITVK SPGREPGREH LNGVAMNVRT
3010
GSAQADGSDS EKP
Length:3,013
Mass (Da):329,311
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC1BA5090CFBA5354
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
NDHI03003480 Genomic DNA Translation: PNJ37212.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NDHI03003480 Genomic DNA Translation: PNJ37212.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

More...
GPCRDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR002126 Cadherin-like_dom
IPR015919 Cadherin-like_sf
IPR020894 Cadherin_CS
IPR013320 ConA-like_dom_sf
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR032471 GAIN_dom_N
IPR017981 GPCR_2-like
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR000832 GPCR_2_secretin-like
IPR000203 GPS
IPR009030 Growth_fac_rcpt_cys_sf
IPR002049 Laminin_EGF
IPR001791 Laminin_G
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00028 Cadherin, 8 hits
PF00008 EGF, 2 hits
PF16489 GAIN, 1 hit
PF01825 GPS, 1 hit
PF00053 Laminin_EGF, 1 hit
PF02210 Laminin_G_2, 2 hits
PRINTSiPR00205 CADHERIN
PR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00112 CA, 9 hits
SM00181 EGF, 6 hits
SM00179 EGF_CA, 4 hits
SM00180 EGF_Lam, 1 hit
SM00303 GPS, 1 hit
SM00008 HormR, 1 hit
SM00282 LamG, 2 hits
SUPFAMiSSF49313 SSF49313, 9 hits
SSF49899 SSF49899, 2 hits
SSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 2 hits
PS00232 CADHERIN_1, 6 hits
PS00022 EGF_1, 5 hits
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 6 hits
PS01248 EGF_LAM_1, 1 hit
PS50027 EGF_LAM_2, 1 hit
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS50025 LAM_G_DOMAIN, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2J8TW31_PONAB
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2J8TW31
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: June 5, 2019
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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