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Protein
Submitted name:

PLAT isoform 6

Gene

CR201_G0033297

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei231Charge relay systemUniRule annotation1
Active sitei280Charge relay systemUniRule annotation1
Active sitei387Charge relay systemUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
PLAT isoform 6Imported
Gene namesi
ORF Names:CR201_G0033297Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501445874121 – 436Sequence analysisAdd BLAST416

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi89 ↔ 170UniRule annotation
Disulfide bondi110 ↔ 152UniRule annotation
Disulfide bondi141 ↔ 165UniRule annotation
Disulfide bondi173 ↔ 304Interchain (between A and B chains)UniRule annotation
Disulfide bondi216 ↔ 232UniRule annotation
Disulfide bondi224 ↔ 293UniRule annotation
Disulfide bondi318 ↔ 393UniRule annotation
Disulfide bondi350 ↔ 366UniRule annotation
Disulfide bondi383 ↔ 411UniRule annotation

Keywords - PTMi

Disulfide bondUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 81Fibronectin type-IInterPro annotationAdd BLAST43
Domaini88 – 170KringleInterPro annotationAdd BLAST83
Domaini185 – 435Peptidase S1InterPro annotationAdd BLAST251

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

KringlePROSITE-ProRule annotationSAAS annotation, SignalSequence analysis

Family and domain databases

CDDicd00061 FN1, 1 hit
cd00108 KR, 1 hit
cd00190 Tryp_SPc, 1 hit
Gene3Di2.40.20.10, 1 hit
InterProiView protein in InterPro
IPR000083 Fibronectin_type1
IPR000001 Kringle
IPR013806 Kringle-like
IPR018056 Kringle_CS
IPR038178 Kringle_sf
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR026280 Tissue_plasm_act
IPR034811 tPA
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PANTHERiPTHR44617 PTHR44617, 2 hits
PfamiView protein in Pfam
PF00039 fn1, 1 hit
PF00051 Kringle, 1 hit
PF00089 Trypsin, 1 hit
PIRSFiPIRSF001145 Tissue_plasm_act, 2 hits
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00058 FN1, 1 hit
SM00130 KR, 1 hit
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
SSF57440 SSF57440, 1 hit
PROSITEiView protein in PROSITE
PS01253 FN1_1, 1 hit
PS51091 FN1_2, 1 hit
PS00021 KRINGLE_1, 1 hit
PS50070 KRINGLE_2, 1 hit
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2J8TNY3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNAMKRGLCC VLLLCGAVFA LPSQEIHARV RRGARSYQVI CRDEKTQMIY
60 70 80 90 100
QQHQSWLRPV LRSNRVEYCW CNSGRAQCHS VPVRRNSDCY FGNGLAYRGT
110 120 130 140 150
HSLTESGASC LLWNSMILIG KVYTAQNPNA QALGLGKHNY CRNPDGDAKP
160 170 180 190 200
WCHVLKNRRL TWEYCDVPSC STCGLRQYSQ PQFRIKGGLF ADIASHPWQA
210 220 230 240 250
AIFAKHRRSP GERFLCGGIL ISSCWILSAA HCFQERFPPH HLTVILGRTY
260 270 280 290 300
RVVPGEEEQK FEVEKYIVHK EFDDDTYDND IALLQLKSDS SRCAQESSVV
310 320 330 340 350
RTVCLPPADL QLPDWTECEL SGYGKHEALS PFYSERLKEA HVRLYPSSRC
360 370 380 390 400
TSQHLLNRTV TDNMLCAGDT RSGGPQANLH DACQGDSGGP LVCLNDGRMT
410 420 430
LVGIISWGLG CGEKDVPGVY TKVTNYLDWI HDNMRP
Length:436
Mass (Da):49,108
Last modified:March 28, 2018 - v1
Checksum:iE86998F05FAC96A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NDHI03003488 Genomic DNA Translation: PNJ34673.1

Similar proteinsi

Entry informationi

Entry nameiA0A2J8TNY3_PONAB
AccessioniPrimary (citable) accession number: A0A2J8TNY3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: September 12, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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