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Protein

Putative hydroxypyruvate isomerase

Gene

HYI

Organism
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).UniRule annotation

Catalytic activityi

Hydroxypyruvate = 2-hydroxy-3-oxopropanoate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei150Proton donor/acceptorUniRule annotation1
Active sitei249Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionIsomeraseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hydroxypyruvate isomeraseUniRule annotation (EC:5.3.1.22UniRule annotation)
Gene namesi
Name:HYIImported
ORF Names:CR201_G0041957Imported
OrganismiPongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)Imported
Taxonomic identifieri9601 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePongo
Proteomesi
  • UP000001595 Componenti: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi9601.ENSPPYP00000001674

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 220AP_endonuc_2InterPro annotationAdd BLAST196

Sequence similaritiesi

Belongs to the hyi family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4518 Eukaryota
COG3622 LUCA
GeneTreeiENSGT00390000005462
KOiK01816
OrthoDBiEOG091G0KZU
TreeFamiTF312858

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2J8SMD1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPLRFSANL SWLFPELPGL PARVRAAGSS GFEAVEVAWP YAEPPETLAR
60 70 80 90 100
AAREAGLRLV LINTPPGDQE KGEMGLGAVP GRQAAFREGL EQAVRYAKAL
110 120 130 140 150
SCPRIHLMAG RVPQGADRTA VKAEMETVFL ENLRHAAGVL AQEDLVGLLE
160 170 180 190 200
PINTRITDPQ YFLDTPQQAA AILQKVGRPN LQLQMDIFHW QIMDGNLTGN
210 220 230 240 250
IQEFLPIVGH VQVAQVPGRG EPSSPGELNF PYLFQLLEDE GYKGFVGCEY
260 270
QPQGDTVEGL SWLRSYWDRR GHPEAGQ
Length:277
Mass (Da):30,434
Last modified:April 25, 2018 - v1
Checksum:i3C6847E83FDF5A35
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ABGA01079299 Genomic DNA No translation available.
NDHI03003559 Genomic DNA Translation: PNJ21921.1
NDHI03003559 Genomic DNA Translation: PNJ21924.1
RefSeqiXP_002810985.1, XM_002810939.3

Genome annotation databases

EnsembliENSPPYT00000001730; ENSPPYP00000001674; ENSPPYG00000001444
GeneIDi100444062
KEGGipon:100444062

Similar proteinsi

Entry informationi

Entry nameiA0A2J8SMD1_PONAB
AccessioniPrimary (citable) accession number: A0A2J8SMD1
Secondary accession number(s): H2N7P6
Entry historyiIntegrated into UniProtKB/TrEMBL: April 25, 2018
Last sequence update: April 25, 2018
Last modified: May 23, 2018
This is version 2 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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