Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
We will be switching to the new UniProt website soon. Please explore and share your feedback. Take me to the new website.

UniProtKB - A0A2J8PWS3 (A0A2J8PWS3_PANTR)

Entry version 14 (19 Jan 2022)
Sequence version 1 (28 Mar 2018)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

EHMT1 isoform 1

Gene

CK820_G0053530

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
EHMT1 isoform 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:CK820_G0053530Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPan troglodytes (Chimpanzee)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9598 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pan
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000236370 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati811 – 843ANKPROSITE-ProRule annotationAdd BLAST33
Repeati844 – 876ANKPROSITE-ProRule annotationAdd BLAST33
Repeati877 – 901ANKPROSITE-ProRule annotationAdd BLAST25
Repeati911 – 943ANKPROSITE-ProRule annotationAdd BLAST33
Repeati977 – 1009ANKPROSITE-ProRule annotationAdd BLAST33
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1099 – 1162Pre-SETInterPro annotationAdd BLAST64
Domaini1165 – 1282SETInterPro annotationAdd BLAST118

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni69 – 125DisorderedSequence analysisAdd BLAST57
Regioni183 – 233DisorderedSequence analysisAdd BLAST51
Regioni250 – 273DisorderedSequence analysisAdd BLAST24
Regioni378 – 518DisorderedSequence analysisAdd BLAST141
Regioni683 – 756DisorderedSequence analysisAdd BLAST74
Regioni1313 – 1337DisorderedSequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi93 – 125Polar residuesSequence analysisAdd BLAST33
Compositional biasi255 – 273Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi384 – 400Acidic residuesSequence analysisAdd BLAST17
Compositional biasi416 – 434Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi435 – 454Acidic residuesSequence analysisAdd BLAST20
Compositional biasi496 – 516Polar residuesSequence analysisAdd BLAST21

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002110, Ankyrin_rpt
IPR036770, Ankyrin_rpt-contain_sf
IPR038035, EHMT1
IPR043550, EHMT1/EHMT2
IPR007728, Pre-SET_dom
IPR001214, SET_dom

The PANTHER Classification System

More...PANTHERi		PTHR46307, PTHR46307, 1 hit
PTHR46307:SF2, PTHR46307:SF2, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12796, Ank_2, 2 hits
PF13637, Ank_4, 1 hit
PF05033, Pre-SET, 1 hit
PF00856, SET, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01415, ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00248, ANK, 7 hits
SM00468, PreSET, 1 hit
SM00317, SET, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48403, SSF48403, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50088, ANK_REPEAT, 5 hits
PS50867, PRE_SET, 1 hit
PS50280, SET, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2J8PWS3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLDAGRYPH TVAQDTGRYP PCGGAGRWDW RRRTAEAGSV PFFLPAVPAR 
        60         70         80         90        100
GEPQQDCCVK TELLGEAETP MAADEGSAEK QAGEAHMAAD GETNGSCENS 
       110        120        130        140        150
DASSHANAAK HTQDSARVNP QDGTNTLTRI AENGVSERDS EAGKQNHVTA 
       160        170        180        190        200
DDFVQTSVIG SNGYILNKPA LQAQPLRTTS TLASSLPGHA AKTLPGGAGK 
       210        220        230        240        250
GRTPSAFPQT PAAPPATLGE GSADTEDRKL PAPGADVKVH RARKTMPKSV 
       260        270        280        290        300
VGLHAASKDP REVREARDHK EPKEEINKNI SDFGRQQLLP PFPSLHQSLP 
       310        320        330        340        350
QNQCYMATTK SQTACLPFVL AAAVSRKKKR RMGTYSLVPK KKTKVLKQRT 
       360        370        380        390        400
VIEMFKSITH STVGSKGEKD LGASSLHVNG ESLEMDSDED DSEELEEDDS 
       410        420        430        440        450
HGAEQAAAFP TEDSRTSKES MSEADRAQKM DGESEEEQES VDTGEEEEGG 
       460        470        480        490        500
DESDLSSESS IKKKFLKRKG KTDSPWIKPA RKRRRRSRKK PSGALGSESY 
       510        520        530        540        550
KSSAGSAEQT APGDSTGYME VSLDSLDLRV KGILSSQAEG LANGPDVLET 
       560        570        580        590        600
DGLQEVPLCS CRMETPKSRE ITTLANNQCM ATESVDHELG RCTNSVVKYE 
       610        620        630        640        650
LMRPSNKAPL LVLCEDHRGR MVKHQCCPGC GYFCTAGNFM ECQPESSISH 
       660        670        680        690        700
RFHKDCASRV NNASYCPHCG EESSKAKEVT IAKADTTSTV TPVPGQEKGS 
       710        720        730        740        750
ALEGRADTTT GSAAGPPLSE DDKLQGTASH VPEGFDPTGP AGLGRPTPGL 
       760        770        780        790        800
SQGPGKETLE SALIALDSEK PKKLRFHPKQ LYFSARQGEL QKVLLMLVDG 
       810        820        830        840        850
IDPNFKMEHQ NKRSPLHAAA EAGHVDICHM LVQAGANIDT CSEDQRTPLM 
       860        870        880        890        900
EAAENNHLEA VKYLIKAGAL VDPKDAEGST CLHLAAKKGH YEVVQYLLSN 
       910        920        930        940        950
GQMDVNCQDD GGWTPMIWAT EYKHVDLVKL LLSKGSDINI RDNEENICLH 
       960        970        980        990       1000
WAAFSGCVDI AEILLAAKCD LHAVNIHGDS PLHIAARENR YDCVVLFLSR 
      1010       1020       1030       1040       1050
DSDVTLKNKE GETPLQCASL NSQVWSALQM SKALQDSAPD RPSPVERIVS 
      1060       1070       1080       1090       1100
RDIARGYERI PIPCVNAVDS EPCPSNYKYV SQNCVTSPMN IDRNITHLQY 
      1110       1120       1130       1140       1150
CVCIDDCSSS NCMCGQLSMR CWYDKDGRLL PEFNMAEPPL IFECNHACSC 
      1160       1170       1180       1190       1200
WRNCRNRVVQ NGLRARLQLY RTRDMGWGVR SLQDIPLGTF VCEYVGELIS 
      1210       1220       1230       1240       1250
DSEADVREED SYLFDLDNKD GEVYCIDARF YGNVSRFINH HCEPNLVPVR 
      1260       1270       1280       1290       1300
VFMAHQDLRF PRIAFFSTRL IEAGEQLGFD YGERFWDIKG RLFSCRCGSP 
      1310       1320       1330 
KCRHSSAALA QRQASAAQEA QEDGLPDTSS AAAADPL
Length:1,337
Mass (Da):145,969
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i07ED72EE65DBCCBF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
NBAG03000141 Genomic DNA Translation: PNI88467.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NBAG03000141 Genomic DNA Translation: PNI88467.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Family and domain databases

Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR036770, Ankyrin_rpt-contain_sf
IPR038035, EHMT1
IPR043550, EHMT1/EHMT2
IPR007728, Pre-SET_dom
IPR001214, SET_dom
PANTHERiPTHR46307, PTHR46307, 1 hit
PTHR46307:SF2, PTHR46307:SF2, 1 hit
PfamiView protein in Pfam
PF12796, Ank_2, 2 hits
PF13637, Ank_4, 1 hit
PF05033, Pre-SET, 1 hit
PF00856, SET, 1 hit
PRINTSiPR01415, ANKYRIN
SMARTiView protein in SMART
SM00248, ANK, 7 hits
SM00468, PreSET, 1 hit
SM00317, SET, 1 hit
SUPFAMiSSF48403, SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50088, ANK_REPEAT, 5 hits
PS50867, PRE_SET, 1 hit
PS50280, SET, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2J8PWS3_PANTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2J8PWS3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: January 19, 2022
This is version 14 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again