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UniProtKB - A0A2I4D062 (A0A2I4D062_9TELE)

Entry version 18 (10 Feb 2021)
Sequence version 1 (28 Feb 2018)
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Protein
Submitted name:

collagen alpha-1(XVIII) chain-like

Gene

LOC106533750

Organism
Austrofundulus limnaeus
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
collagen alpha-1(XVIII) chain-likeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LOC106533750Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAustrofundulus limnaeusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri52670 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Neoteleostei › Acanthomorphata › Ovalentaria › Atherinomorphae › Cyprinodontiformes › Rivulidae › Austrofundulus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000192220 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 25Sequence analysisAdd BLAST25
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501419390926 – 1248Sequence analysisAdd BLAST1223

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini37 – 226LAM_G_DOMAINInterPro annotationAdd BLAST190

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni226 – 680DisorderedSequence analysisAdd BLAST455
Regioni703 – 729DisorderedSequence analysisAdd BLAST27
Regioni747 – 821DisorderedSequence analysisAdd BLAST75
Regioni850 – 1001DisorderedSequence analysisAdd BLAST152

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi248 – 271PolyampholyteSequence analysisAdd BLAST24
Compositional biasi418 – 433Pro-richSequence analysisAdd BLAST16
Compositional biasi457 – 477Pro-richSequence analysisAdd BLAST21
Compositional biasi533 – 567Pro-richSequence analysisAdd BLAST35
Compositional biasi800 – 817Pro-richSequence analysisAdd BLAST18
Compositional biasi933 – 964Pro-richSequence analysisAdd BLAST32

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

CollagenImportedARBA annotation, SignalSequence analysis

Phylogenomic databases

Database of Orthologous Groups

More...OrthoDBi		1362001at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.10.100.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR016186, C-type_lectin-like/link_sf
IPR008160, Collagen
IPR010515, Collagenase_NC10/endostatin
IPR013320, ConA-like_dom_sf
IPR016187, CTDL_fold
IPR001791, Laminin_G

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01391, Collagen, 5 hits
PF06482, Endostatin, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00210, TSPN, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49899, SSF49899, 1 hit
SSF56436, SSF56436, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2I4D062-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSCIPPWSI GFSLLLRLCC LHSSAYQLLE GLGSQSDLDL TELIGVPLPP 
        60         70         80         90        100
SISFVTGFEG YPAYSFGPYA NVGRLTKSFI PDPFYHDFAI TVTAKPTTRR 
       110        120        130        140        150
GGVLFAITDA YQKIVQLGVA LSEVEDGAQS IILYYTDPET RDGTQEAASF 
       160        170        180        190        200
KMGDLTGRWA RFTLTVQGAE IRLYMDCEEY HKVAFTRSAH PLTFDASSGI 
       210        220        230        240        250
FVGNAGGTGL TRFVGSIQQL LLKSDATAPD DQCEEDDPYA SGYGSGEEDY 
       260        270        280        290        300
GDRNEIEEVK KIVEEREYTM PLPELDPTYS GPVRAPPTEV PLSDDEDMEE 
       310        320        330        340        350
SSGQDFETTI NKVRSFPTRA PAFEPDSVIG GQKGERGEPG PAGPPGAPGS 
       360        370        380        390        400
PGKASDARGE PGPKGPQGAQ GYQGVPGRPG TPGQPGSKGE LGSPGPTGFP 
       410        420        430        440        450
GEQGEPGPKG EKGDPGVGRP GPPGPPGPPG PPNKSSVALL EGSGFEDFDN 
       460        470        480        490        500
DAEIIRGPPG PPGPPGLPGP PGTPSADVAL GPPGAPGKDG KDGKKGEPGL 
       510        520        530        540        550
PGVDGGDGDP GPAGEKGDKG EPGVSGQPGP KGDLGPPGFP GLPGSPGPEG 
       560        570        580        590        600
QPGPRGLPGP PGPPGPVGRG FDRTFEDLEG SGMLGDFESI PIPQGPPGIR 
       610        620        630        640        650
GPQGPKGKXG LDGIPGPPGQ KGEPGVRGPP GIPGFEGLKG AEGQKGDKGD 
       660        670        680        690        700
PGQKGQAGRD GLSLPGLPGP PGPPGPVTNL RDMLLNSTDG AFNFSGIFEA 
       710        720        730        740        750
QGFAGPQGPK GDIGLPGLQG PQGLKGEKGE PASVIAADGS LMFDMAGSTM 
       760        770        780        790        800
PKGIKGDRGV TGPPGITGPI GPPGIKGEIG IPGRPGXSGL IGPKGEKGDP 
       810        820        830        840        850
QGRPGPPGPP GPPGRPGVFN CPKGKXIAKY SCMMHAIPGM VKAQCKEITE 
       860        870        880        890        900
PNSGGTIATG YCQQGPKGEK GDTGPPGLPA PPSTYLSKGT WGDKGSKGEK 
       910        920        930        940        950
GEKGDAGYPG QPGFPGRSGL VGPKGESVLG PPGQPGMPGP PGNPGYGRPG 
       960        970        980        990       1000
SVGPPGPPGP PGTPGFLSGY GSALSIAGPP GPPGPPGSPG ASSNSATLKT 
      1010       1020       1030       1040       1050
FSTRESMMQQ TLRVEEGTLA YVRATGSLFL KVSQGWKEIQ LGNLIYLSSN 
      1060       1070       1080       1090       1100
ILQQDEPQAA NQVRGQAVQR IRSIKQRLNL VALNQPHSGN MLGLNRADRM 
      1110       1120       1130       1140       1150
CYEQAKAMGL APNYRAFIST NRQDLKNVVY PAFRENLPVT NLRGDVLFLN 
      1160       1170       1180       1190       1200
WRSIFRGDSG TINTRIPIFS FDGRDVSADS FWPRKSIWHG SGNRGVRLLD 
      1210       1220       1230       1240 
KHCETWQADD ISVMGQSSSL TSGLLLGQET RSCSNEYIVL CIETHKTY
Length:1,248
Mass (Da):128,423
Last modified:February 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i84B550215E6F1726
GO

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_013885636.1, XM_014030182.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		106533750

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		alim:106533750

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_013885636.1, XM_014030182.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

Genome annotation databases

GeneIDi106533750
KEGGialim:106533750

Phylogenomic databases

OrthoDBi1362001at2759

Family and domain databases

Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186, C-type_lectin-like/link_sf
IPR008160, Collagen
IPR010515, Collagenase_NC10/endostatin
IPR013320, ConA-like_dom_sf
IPR016187, CTDL_fold
IPR001791, Laminin_G
PfamiView protein in Pfam
PF01391, Collagen, 5 hits
PF06482, Endostatin, 2 hits
SMARTiView protein in SMART
SM00210, TSPN, 1 hit
SUPFAMiSSF49899, SSF49899, 1 hit
SSF56436, SSF56436, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2I4D062_9TELE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2I4D062
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: February 10, 2021
This is version 18 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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