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Protein

Homeobox protein cut-like

Gene

cux1

Organism
Austrofundulus limnaeus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi1172 – 1231HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein cut-likeUniRule annotation
Gene namesi
Name:cux1Imported
OrganismiAustrofundulus limnaeusImported
Taxonomic identifieri52670 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesRivulidaeAustrofundulus
Proteomesi
  • UP000192220 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini593 – 680CUTInterPro annotationAdd BLAST88
Domaini886 – 974CUTInterPro annotationAdd BLAST89
Domaini1045 – 1132CUTInterPro annotationAdd BLAST88
Domaini1170 – 1230HomeoboxInterPro annotationAdd BLAST61

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili17 – 37Sequence analysisAdd BLAST21
Coiled coili68 – 88Sequence analysisAdd BLAST21
Coiled coili119 – 177Sequence analysisAdd BLAST59
Coiled coili187 – 228Sequence analysisAdd BLAST42
Coiled coili237 – 274Sequence analysisAdd BLAST38
Coiled coili296 – 330Sequence analysisAdd BLAST35
Coiled coili335 – 355Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the CUT homeobox family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxPROSITE-ProRule annotation

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR003350 CUT_dom
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 3 hits
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 3 hits
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 3 hits
PROSITEiView protein in PROSITE
PS51042 CUT, 3 hits
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

A0A2I4BFJ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAANAGSMFQ YWKRFDLQQL QKELDATATQ LANRQDESEQ SRKKLIDLSR
60 70 80 90 100
EFKKTTPEDL RKQVAPLLKS FQGEIDALSK RSKEAEAAFL NVYKKIIDVP
110 120 130 140 150
DPVPVLELAQ QLQLKLQRMH DIETENTKLR ETLEDYNKEF AEVKNQEVTI
160 170 180 190 200
KALKEKIREY EQTLKNQAEN LAQEKQLQLH NDYAEKERKL QESQDSMSSR
210 220 230 240 250
LKEAETKVQS LQTALETTQA ELFDLKTKYD EESTAKVDEI EMVMTDLERA
260 270 280 290 300
NQRAEAAQRE AESLREQLSL SNQSQQPSSP SKADPDSEQA AEAASHSSLE
310 320 330 340 350
AELRAKERET AQLVEDVQRL QASLTKLRET TSSQILQLEQ QLSSKSAVLK
360 370 380 390 400
ELEEKLESQA DYEEVKKELS ILKTMEFGTS DSVQDSSKPL EVLLLEKNRA
410 420 430 440 450
LQSESAALRI ANTELSGSAG RKGTEESTTT KEDTVNSDPS SSPTPPPPSV
460 470 480 490 500
PSSSQLPLSR AHTDSLNTAT TSGETHPFTP TGIGQELYSP MFPLVGGKMA
510 520 530 540 550
LNSLIQRQLL QTFYSKALQE SSGIHSGALL FTPFTPALSS IPTSTPGSGS
560 570 580 590 600
ATIPLAASSP QPPPASPDMA PVNGSSTAGS APSPSPSHSD ANTGSVLDGE
610 620 630 640 650
DMDTAEIARQ VKEQLIKHNI GQRVFGHYVL GLSQGSVSEI LARPKPWNKL
660 670 680 690 700
TIRGKEPFHK MRQFLADEQN ILALRSIQGR QREGSGQPQL SRVFQDVPKR
710 720 730 740 750
RSISDTPSHT GNITARVRTP EAGSDEAIKS ILEQAKRELQ VQKADLSHAP
760 770 780 790 800
PSYTGLKGGG GGGVASGGGS GSDEAIRSIL EQARREMEAN QAALEPILKA
810 820 830 840 850
SSSSSSSALS QRDILNSPLT APLPPYNPLA LSLKKPPSSL LSSPSSPSPI
860 870 880 890 900
LDFSSGGKRE GRASSGIDMS ADGLFRQGRA SEGSARSGSA AGVGYWREQW
910 920 930 940 950
WSNMHSDPRR TMSSQTGEEN HHQEDSKEGI LSDSLSRHKP WNKLNQRSRE
960 970 980 990 1000
PYLRMQPWVN GDQGQNAHVQ QTQNQAEGTP KTSASCSPAP ESPLSSAEES
1010 1020 1030 1040 1050
VNGLSGDPLA SQSSGLKPPS EDPSGGESQP GTPLPLPGHS GLSIQEMVAM
1060 1070 1080 1090 1100
SPELDTYAIT KKVKEVLTDN NLGQRLFGET ILGLTQGSVS DLLARPKPWH
1110 1120 1130 1140 1150
KLSLKGREPF VRMQLWLQDP HSVEKLMDMK RLEKKAYMKR RLSSLSDGHS
1160 1170 1180 1190 1200
VEGALVGSDY MQGSQSPGQQ QLKKPRVVLG PEEKEALKKA YQQKPYPSPK
1210 1220 1230 1240 1250
TIEELASQLN LKTSTVINWF HNYRSRIRRE LFIEEIQAAG GVVPGSDGGS
1260 1270 1280 1290 1300
PSLRGSKSGE GDSCDGTESE GTVESRQGLG MSLEDHRGAC KDHSMETESE
1310 1320 1330 1340 1350
VGGSNNSPAQ LDCTTSGLAG PGSSCGQSGL GLFSLTEASS SSSASSTNIP
1360 1370 1380 1390
ASGPTRNPRD NNLRKKKAAN LNNIIHRLEK AASKEDPSEW EF
Length:1,392
Mass (Da):151,400
Last modified:February 28, 2018 - v1
Checksum:i14180325DDBEF6F0
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I4BFJ6A0A2I4BFJ6_9TELE
DNA-binding protein SATB
cux1
1,262Annotation score:
A0A2I4BFJ1A0A2I4BFJ1_9TELE
Homeobox protein cut-like
cux1
1,394Annotation score:
A0A2I4BFI4A0A2I4BFI4_9TELE
Homeobox protein cut-like
cux1
1,422Annotation score:
A0A2I4BFK3A0A2I4BFK3_9TELE
Homeobox protein cut-like
cux1
1,421Annotation score:
A0A2I4BFJ5A0A2I4BFJ5_9TELE
Homeobox protein cut-like
cux1
1,364Annotation score:
A0A2I4BFJ3A0A2I4BFJ3_9TELE
protein CASP isoform X6
cux1
700Annotation score:
A0A2I4BFK8A0A2I4BFK8_9TELE
protein CASP isoform X7
cux1
670Annotation score:

Sequence databases

RefSeqiXP_013866510.1, XM_014011056.1

Genome annotation databases

GeneIDi106519396

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_013866510.1, XM_014011056.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi106519396

Organism-specific databases

CTDi1523

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR003350 CUT_dom
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR010982 Lambda_DNA-bd_dom_sf
PfamiView protein in Pfam
PF02376 CUT, 3 hits
PF00046 Homeobox, 1 hit
SMARTiView protein in SMART
SM01109 CUT, 3 hits
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF47413 SSF47413, 3 hits
PROSITEiView protein in PROSITE
PS51042 CUT, 3 hits
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2I4BFJ7_9TELE
AccessioniPrimary (citable) accession number: A0A2I4BFJ7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: May 23, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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