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Protein
Submitted name:

EGF, latrophilin and seven transmembrane domain-containing protein 1

Gene

adgrl4

Organism
Austrofundulus limnaeus
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
EGF, latrophilin and seven transmembrane domain-containing protein 1Imported
Gene namesi
Name:adgrl4Imported
OrganismiAustrofundulus limnaeusImported
Taxonomic identifieri52670 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeCyprinodontiformesRivulidaeAustrofundulus
Proteomesi
  • UP000192220 Componenti: Genome assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei488 – 508HelicalSequence analysisAdd BLAST21
Transmembranei520 – 539HelicalSequence analysisAdd BLAST20
Transmembranei551 – 579HelicalSequence analysisAdd BLAST29
Transmembranei588 – 606HelicalSequence analysisAdd BLAST19
Transmembranei626 – 649HelicalSequence analysisAdd BLAST24
Transmembranei670 – 694HelicalSequence analysisAdd BLAST25
Transmembranei700 – 722HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501418688229 – 741Sequence analysisAdd BLAST713

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 106EGF-likeInterPro annotationAdd BLAST42
Domaini115 – 152EGF-likeInterPro annotationAdd BLAST38
Domaini422 – 473GPSInterPro annotationAdd BLAST52
Domaini482 – 723G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST242

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR032471 GAIN_dom_N
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR009030 Growth_fac_rcpt_cys_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF07645 EGF_CA, 2 hits
PF16489 GAIN, 1 hit
PF01825 GPS, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00181 EGF, 3 hits
SM00179 EGF_CA, 2 hits
SM00303 GPS, 1 hit
SUPFAMiSSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 2 hits
PS50026 EGF_3, 2 hits
PS01187 EGF_CA, 2 hits
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2I4AIV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESLLKSPMK LVLFTAWFWS LLDTGCLSIC DTCHQNATCK VMNGSNSGCF
60 70 80 90 100
CNHGYTGDGK HFCKDDNECQ NVTDICGDRG HCTNTEGSYY CTCVPGYTST
110 120 130 140 150
GQSRFQPNDG TECTDIDECK SGXVCGPNSV CHNTNGSFDC TCQRDYISTS
160 170 180 190 200
GSKRFHPGRG ARCKEHPQKH CHDDAECTTQ AVNSTLEKLS NLTEPQSLLG
210 220 230 240 250
EIAKQTSGEL TSVEVIAYVE ALSRSASTLT AAEKDYSVKP SAINSTLSKL
260 270 280 290 300
VKAANNLVEK DELVAWSRMK DERRGPTLTK LLHLVEESAL SLGNNVKTPT
310 320 330 340 350
EIQIKAKEME LKLLTLHSQR VKTKVSFSTS GGHISLTPKL TPGKDRNGSV
360 370 380 390 400
SVVFVRYDSI GDILKPSSDP GVTDYSRYAG TGEITVNSQV VAAAVKPADI
410 420 430 440 450
YQLDHVTFTL RHAEPIDVKV DVTKCAFWEY EVDSLQGRWS THGCKTIQVS
460 470 480 490 500
SNATSCSCDH LTHFAILMSS GRANLAAHNT ILTRITQLGM IISLICLSMC
510 520 530 540 550
IFTFWFFSEI QSTRTTIHKN LCCSLFMAEF IFLVGINMNT HKLFCSVIAG
560 570 580 590 600
LLHYFFLAAF AWMCIEGIHL YLIVVGVIYN KGFLHRNFYI FGYGSPAVVV
610 620 630 640 650
AISATLGSKY YGTERVCWLS TENHFVWSFI GPACLIILVN LLAFGVIMFK
660 670 680 690 700
VYRHTAVKKP EISHYENIRS CARGAMALLF VLGATWTFGV LHILHETTLT
710 720 730 740
AYLFTISNAF QGMFIFIFLC VLSRKIQEEY YRLFKNIPCR S
Length:741
Mass (Da):82,185
Last modified:February 28, 2018 - v1
Checksum:iBCFD8049EAD6A19F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei741Imported1

Sequence databases

RefSeqiXP_013855438.1, XM_013999984.1

Genome annotation databases

GeneIDi106511227

Similar proteinsi

Entry informationi

Entry nameiA0A2I4AIV9_9TELE
AccessioniPrimary (citable) accession number: A0A2I4AIV9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: May 23, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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