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Protein
Submitted name:

CHRNG isoform 2

Gene

CHRNG

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
CHRNG isoform 2Imported
Submitted name:
Cholinergic receptor nicotinic gamma subunitImported
Gene namesi
Name:CHRNGImported
ORF Names:CK820_G0010827Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 2B

Organism-specific databases

VGNCiVGNC:138 CHRNG

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei190 – 212HelicalSequence analysisAdd BLAST23
Transmembranei224 – 244HelicalSequence analysisAdd BLAST21
Transmembranei256 – 279HelicalSequence analysisAdd BLAST24
Transmembranei423 – 445HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_501508207523 – 465Sequence analysisAdd BLAST443

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 119Neur_chan_LBDInterPro annotationAdd BLAST94
Domaini117 – 189Neur_chan_LBDInterPro annotationAdd BLAST73
Domaini196 – 440Neur_chan_membInterPro annotationAdd BLAST245

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00910000144023

Family and domain databases

Gene3Di2.70.170.10, 2 hits
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 2 hits
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 2 hits
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2I3TQG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHGGQGPLLL LLLLAVCLGA QGRNQEERLL ADLMQNYDPN LRPAERDSDV
60 70 80 90 100
VNVSLKLTLT NLISLNEREE ALTTNVWIEM QWCDYRLRWD PRDYEGLWVL
110 120 130 140 150
RVPSTMVWRP DIVLENKSQT YSTNEIDLQL SQEDGQTIEW IFIDPEAFTE
160 170 180 190 200
NGEWAIQHRP AKMLLDPAAP AQEAGHQKVV FYLLIQRKPL FYVINIIAPC
210 220 230 240 250
VLISSVAILI YFLPAKAGGQ KCTVAINVLL AQTVFLFLVA KKVPETSQAV
260 270 280 290 300
PLISKYLTFL LVVTILIVVN AVVVLNVSLR SPHTHSMARG VRKVFLRLLP
310 320 330 340 350
QLLRMHVRPL APATVQDTQS RLQNGSSGWS ITTGEEVALC LPRSELLFQQ
360 370 380 390 400
WQRQGLVAAA LEKLEKGPEL GPSQFCGSLK QAAPAIQACV EACNLIACAR
410 420 430 440 450
HQQSHFDNGN EEWFLVGRVL DRVCFLAMLS LFVCGTAGIF LMAHYNRVPA
460
LPFPGDPRPY LPSPD
Length:465
Mass (Da):52,046
Last modified:February 28, 2018 - v1
Checksum:iBF954954135773A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04056642 Genomic DNA No translation available.
NBAG03000230 Genomic DNA Translation: PNI70328.1

Genome annotation databases

EnsembliENSPTRT00000083215; ENSPTRP00000091466; ENSPTRG00000022726

Similar proteinsi

Entry informationi

Entry nameiA0A2I3TQG7_PANTR
AccessioniPrimary (citable) accession number: A0A2I3TQG7
Secondary accession number(s): A0A2J8NEX8
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: June 20, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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