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Protein
Submitted name:

GIT ArfGAP 2

Gene

GIT2

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
GIT ArfGAP 2Imported
Submitted name:
GIT2 isoform 9Imported
Gene namesi
Name:GIT2Imported
ORF Names:CK820_G0015941Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 12

Organism-specific databases

VGNCiVGNC:8597 GIT2

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 124Arf-GAPInterPro annotationAdd BLAST124
Domaini132 – 221ANK_REP_REGIONInterPro annotationAdd BLAST90
Repeati166 – 198ANKPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili407 – 427Sequence analysisAdd BLAST21
Coiled coili593 – 613Sequence analysisAdd BLAST21

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

GeneTreeiENSGT00930000150886

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR022018 GIT1_C
IPR013724 GIT_SHD
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF01412 ArfGap, 1 hit
PF12205 GIT1_C, 1 hit
PF08518 GIT_SHD, 2 hits
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SM00105 ArfGap, 1 hit
SM00555 GIT, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit
PS50115 ARFGAP, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

A0A2I3SVH3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKRLRSSEV CADCSGPDPS WASVNRGTFL CDECCSVHRS LGRHISQVRH
60 70 80 90 100
LKHTPWPPTL LQMVETLYNN GANSIWEHSL LDPASIMSGR RKANPQDKVH
110 120 130 140 150
PNKAEFIRAK YQMLAFVHRL PCRDDDSVTA KDLSKQLHSS VRTGNLETCL
160 170 180 190 200
RLLSLGAQAN FFHPEKGNTP LHVASKAGQI LQAELLAVYG ADPGTQDSSG
210 220 230 240 250
KTPVDYARQG GHHELAERLV EIQYELTDRL AFYLCGRKPD HKNGQHFIIP
260 270 280 290 300
QMADSLDLSE LAKAAKKKLQ SLSNHLFEEL AMDVYDEVDR RETDAVWLAT
310 320 330 340 350
QNHSALVTET TVVPFLPVNP EYSSTRNQGR QKLARFNAHE FATLVIDILS
360 370 380 390 400
DAKRRQQGSS LSGSKDNVEL ILKTINNQHS VESQDNDQPD YDSVASDEDT
410 420 430 440 450
DLETTASKTN RQKLQTLQSE NSNLRKQATT NVYQVQTGSE YTDTSNHSSL
460 470 480 490 500
KRRPSARGSR PMSMYETGSG QKPYLPMGEA SRPEESRTRL QPFPAHIGRS
510 520 530 540 550
ALVTSSSSLP SFPSTLSWSR DESARRASRL EKQNSTPESD YDNTPNDMEP
560 570 580 590 600
DGMGSSRKGR QRSMVWPGDG LVPDTAEPHV APSPTLPSTE DVIRKTEQIT
610 620 630 640 650
KNIQELLRAA QENKHDSYIP CSERIHVAVT EMAALFPKKP KSDMVRTSLR
660 670 680 690 700
LLTSSAYRLQ SECKKTLPGD PGSPTDVQLV TQQVIQCAYD IAKAAKQLVT

ITTKENNN
Length:708
Mass (Da):78,837
Last modified:February 28, 2018 - v1
Checksum:i8C79CC48DA59C52A
GO

Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
K7C3J8K7C3J8_PANTR
G protein-coupled receptor kinase i...
GIT2 CK820_G0015941
759Annotation score:
K7BNC8K7BNC8_PANTR
G protein-coupled receptor kinase i...
GIT2 CK820_G0015941
471Annotation score:
K7AK20K7AK20_PANTR
G protein-coupled receptor kinase i...
GIT2 CK820_G0015941
729Annotation score:
A0A2I3SFN4A0A2I3SFN4_PANTR
GIT ArfGAP 2
GIT2
760Annotation score:
A0A2I3TQH8A0A2I3TQH8_PANTR
GIT ArfGAP 2
GIT2 CK820_G0015941
681Annotation score:
A0A2I3REA3A0A2I3REA3_PANTR
GIT ArfGAP 2
GIT2 CK820_G0015941
631Annotation score:
A0A2I3SBZ5A0A2I3SBZ5_PANTR
GIT ArfGAP 2
GIT2
681Annotation score:
A0A2I3SMK1A0A2I3SMK1_PANTR
GIT ArfGAP 2
GIT2 CK820_G0015941
421Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04070357 Genomic DNA No translation available.
NBAG03000240 Genomic DNA Translation: PNI64766.1

Genome annotation databases

EnsembliENSPTRT00000078278; ENSPTRP00000080957; ENSPTRG00000005433

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04070357 Genomic DNA No translation available.
NBAG03000240 Genomic DNA Translation: PNI64766.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000078278; ENSPTRP00000080957; ENSPTRG00000005433

Organism-specific databases

VGNCiVGNC:8597 GIT2

Phylogenomic databases

GeneTreeiENSGT00930000150886

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
3.30.40.160, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR037278 ARFGAP/RecO
IPR001164 ArfGAP_dom
IPR038508 ArfGAP_dom_sf
IPR022018 GIT1_C
IPR013724 GIT_SHD
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF01412 ArfGap, 1 hit
PF12205 GIT1_C, 1 hit
PF08518 GIT_SHD, 2 hits
PRINTSiPR00405 REVINTRACTNG
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SM00105 ArfGap, 1 hit
SM00555 GIT, 2 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF57863 SSF57863, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 1 hit
PS50115 ARFGAP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2I3SVH3_PANTR
AccessioniPrimary (citable) accession number: A0A2I3SVH3
Secondary accession number(s): A0A2J8MZ29
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: November 7, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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