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Entry version 7 (05 Jun 2019)
Sequence version 1 (28 Feb 2018)
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Protein

Voltage-dependent L-type calcium channel subunit alpha

Gene

CACNA1C

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionCalcium channelUniRule annotation, Ion channel, Voltage-gated channelUniRule annotation
Biological processCalcium transport, Ion transport, Transport
LigandCalcium

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Voltage-dependent L-type calcium channel subunit alphaUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CACNA1CImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPan troglodytes (Chimpanzee)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9598 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002277 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:51248 CACNA1C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei77 – 96HelicalSequence analysisAdd BLAST20
Transmembranei108 – 125HelicalSequence analysisAdd BLAST18
Transmembranei181 – 203HelicalSequence analysisAdd BLAST23
Transmembranei442 – 460HelicalSequence analysisAdd BLAST19
Transmembranei568 – 590HelicalSequence analysisAdd BLAST23
Transmembranei644 – 670HelicalSequence analysisAdd BLAST27
Transmembranei818 – 837HelicalSequence analysisAdd BLAST20
Transmembranei849 – 871HelicalSequence analysisAdd BLAST23
Transmembranei891 – 914HelicalSequence analysisAdd BLAST24
Transmembranei935 – 968HelicalSequence analysisAdd BLAST34
Transmembranei1060 – 1086HelicalSequence analysisAdd BLAST27
Transmembranei1137 – 1158HelicalSequence analysisAdd BLAST22
Transmembranei1170 – 1190HelicalSequence analysisAdd BLAST21
Transmembranei1276 – 1294HelicalSequence analysisAdd BLAST19
Transmembranei1370 – 1393HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1527 – 1561Ca_chan_IQInterPro annotationAdd BLAST35

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni361 – 388DisorderedSequence analysisAdd BLAST28
Regioni681 – 778DisorderedSequence analysisAdd BLAST98
Regioni1647 – 1714DisorderedSequence analysisAdd BLAST68

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1488 – 1508Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi681 – 726PolyampholyteSequence analysisAdd BLAST46
Compositional biasi1647 – 1692PolarSequence analysisAdd BLAST46

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. [View classification]UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156127

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.120.350, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR031688 CAC1F_C
IPR031649 GPHH_dom
IPR005821 Ion_trans_dom
IPR014873 VDCC_a1su_IQ
IPR005451 VDCC_L_a1csu
IPR005446 VDCC_L_a1su
IPR002077 VDCCAlpha1
IPR027359 Volt_channel_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08763 Ca_chan_IQ, 1 hit
PF16885 CAC1F_C, 2 hits
PF16905 GPHH, 1 hit
PF00520 Ion_trans, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00167 CACHANNEL
PR01630 LVDCCALPHA1
PR01635 LVDCCALPHA1C

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01062 Ca_chan_IQ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

A0A2I3SCM5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGCRTNVTW HGSKDRLFWE NLPRPKVNKR SHIPQPFHLK KRYARSRMLL
60 70 80 90 100
GPHHTPRPMA LSFYRAIKQE KAERVEYLFL IIFTVEAFLK VIAYGLLFHP
110 120 130 140 150
NAYLRNGWNL LDFIIVVVGL FSAILEQATK ADGANALGGK GAGFDVKALR
160 170 180 190 200
AFRVLRPLRL VSGVPSLQVV LNSIIKAMVP LLHIALLVLF VIIIYAIIGL
210 220 230 240 250
ELFMGKMHKT CYNQEGIADV PAEDDPSPCA LETGHGRQCQ NGTVCKPGWD
260 270 280 290 300
GPKHGITNFD NFAFAMLTVF QCITMEGWTD VLYWVRSMSG QSEGGGTAAV
310 320 330 340 350
NPSLTPPFLL LPMVLGSHTE FSKEREKAKA RGDFQKLREK QQLEEDLKGY
360 370 380 390 400
LDWITQAEDI DPENEDEGMD EEKPRNMSMP TSETESVNTE NVAGGDIEGE
410 420 430 440 450
NCGARLAPGA GAFSGAWVEN RYWRRWNRFC RRKCRAAVKS NVFYWLVIFL
460 470 480 490 500
VFLNTLTIAS EHYNQPHWLT EVQDTANKAL LALFTAEMLL KMYSLGLQAY
510 520 530 540 550
FVSLFNRFDC FVVCGGILET ILVETKIMSP LGISVLRCVR LLRIFKITRY
560 570 580 590 600
WNSLSNLVAS LLNSVRSIAS LLLLLFLFII IFSLLGMQLF GGKFNFDEMQ
610 620 630 640 650
TRRSTFDNFP QSLLTVFQIL TGEDWNSVMY DGIMAYGGPS FPGMLVCIYF
660 670 680 690 700
IILFICGNYI LLNVFLAIAV DNLADAESLT SAQKEEEEEK ERKKLARTAS
710 720 730 740 750
PEKKQELVEK PAVGESKEEK IELKSITADG ESPPATKINM DDLQPNENED
760 770 780 790 800
KSPYPNPETT GEEDEEEPEM PVGPRPRPLS ELHLKEKAVP MPEASAFFIF
810 820 830 840 850
SSNNRFRLQC HRIVNDTIFT NLILFFILLS SISLAAEDPV QHTSFRNHIL
860 870 880 890 900
FYFDIVFTTI FTIEIALKMT AYGAFLHKGS FCRNYFNILD LLVVSVSLIS
910 920 930 940 950
FGIQSSAINV VKILRVLRVL RPLRAINRAK GLKHVVQCVF VAIRTIGNIV
960 970 980 990 1000
IVTTLLQFMF ACIGVQLFKG KLYTCSDSSK QTEAECKGNY ITYKDGEVDH
1010 1020 1030 1040 1050
PIIQPRSWEN SKFDFDNVLA AMMALFTVST FEGWPELLYR SIDSHTEDKG
1060 1070 1080 1090 1100
PIYNYRVEIS IFFIIYIIII AFFMMNIFVG FVIVTFQEQG EQEYKNCELD
1110 1120 1130 1140 1150
KNQRQCVEYA LKARPLRRYI PKNQHQYKVW YVVNSTYFEY LMFVLILLNT
1160 1170 1180 1190 1200
ICLAMQHYGQ SCLFKIAMNI LNMLFTGLFT VEMILKLIAF KPKHYFCDAW
1210 1220 1230 1240 1250
NTFDALIVVG SIVDIAITEV NPAEHTQCSP SMNAEENSRI SITFFRLFRV
1260 1270 1280 1290 1300
MRLVKLLSRG EGIRTLLWTF IKSFQALPYV ALLIVMLFFI YAVIGMQVFG
1310 1320 1330 1340 1350
KIALNDTTEI NRNNNFQTFP QAVLLLFRCA TGEAWQDIML ACMPGKKCAP
1360 1370 1380 1390 1400
ESEPSNSTEG ETPCGSSFAV FYFISFYMLC AFLIINLFVA VIMDNFDYLT
1410 1420 1430 1440 1450
RDWSILGPHH LDEFKRIWAE YDPEAKGRIK HLDVVTLLRR IQPPLGFGKL
1460 1470 1480 1490 1500
CPHRVACKRL VSMNMPLNSD GTVMFNATLF ALVRTALRIK TEGNLEQANE
1510 1520 1530 1540 1550
ELRAIIKKIW KRTSMKLLDQ VVPPAGDDEV TVGKFYATFL IQEYFRKFKK
1560 1570 1580 1590 1600
RKEQGLVGKP SQRNALSLQA GLRTLHDIGP EIRRAISGDL TAEEELDKAM
1610 1620 1630 1640 1650
KEAVSAASED DIFRRAGGLF GNHVSYYQSD GRSAFPQTFT TQRPLHINKA
1660 1670 1680 1690 1700
GSSQGDTESP SHEKLVDSTF TPSSYSSTGS NANINNANNT ALGRLPRPAG
1710 1720 1730 1740 1750
YPSTVSTVEG HGPPLSPAIR VQEVAWKLSS NRMHCCDMLD GGTFPPALGP
1760 1770 1780 1790 1800
RGAPPCLHQQ LQGSLAGLRE DTPCIVPGRL AVSDVFLHLG YCRCHSRESQ
1810 1820 1830 1840 1850
AAMAGQEETS QDETYEVKMN HDAEACSEPS LLSTEMLSYQ DDENRQLTLP
1860 1870 1880 1890 1900
EEDKRDIRQS PKRGFLRSAS LGRRASFHLE CLKRQKDRGG DISQKTVLPL
1910 1920 1930 1940 1950
HLVHHQALAV AGLSPLLQRS HSPASFPRPF ATPPATPGSR GWPPQLVPTL
1960 1970 1980 1990 2000
RLEGVESSEK LNSSFPSIHC GSWAETTPGG GGSSAARRAR PVSLMVPSQA
2010 2020 2030 2040 2050
GAPGRQFHGS ASSLVEAVLI SEGLGQFAQD PKFIEVTTQE LADACDMTIE
2060 2070 2080 2090 2100
EMESAADNIL SGGAPQSPNG ALLPFVNCRD AGQDRAGGEE DAGCVRARGR
2110
LSEEELQDSR VYVSSL
Length:2,116
Mass (Da):237,299
Last modified:February 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD60B7CC64FBA03A4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H2Q573H2Q573_PANTR
Voltage-dependent L-type calcium ch...
CACNA1C CK820_G0037411
2,186Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3TGU1A0A2I3TGU1_PANTR
Voltage-dependent L-type calcium ch...
CACNA1C CK820_G0037411
2,163Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3SX18A0A2I3SX18_PANTR
Voltage-dependent L-type calcium ch...
CACNA1C CK820_G0037411
2,173Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3SXU6A0A2I3SXU6_PANTR
Voltage-dependent L-type calcium ch...
CACNA1C CK820_G0037411
2,155Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3TGV7A0A2I3TGV7_PANTR
Voltage-dependent L-type calcium ch...
CACNA1C CK820_G0037411
2,173Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3T839A0A2I3T839_PANTR
Voltage-dependent L-type calcium ch...
CACNA1C
2,095Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3SAF6A0A2I3SAF6_PANTR
Voltage-dependent L-type calcium ch...
CACNA1C
2,058Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3TWJ0A0A2I3TWJ0_PANTR
Voltage-dependent L-type calcium ch...
CACNA1C CK820_G0037411
2,179Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2I3SQQ0A0A2I3SQQ0_PANTR
CACNA1C isoform 23
CACNA1C CK820_G0037411
829Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AACZ04028126 Genomic DNA No translation available.
AACZ04028127 Genomic DNA No translation available.
AACZ04028128 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPTRT00000093095; ENSPTRP00000074247; ENSPTRG00000004526

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04028126 Genomic DNA No translation available.
AACZ04028127 Genomic DNA No translation available.
AACZ04028128 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000093095; ENSPTRP00000074247; ENSPTRG00000004526

Organism-specific databases

VGNCiVGNC:51248 CACNA1C

Phylogenomic databases

GeneTreeiENSGT00940000156127

Family and domain databases

Gene3Di1.20.120.350, 4 hits
InterProiView protein in InterPro
IPR031688 CAC1F_C
IPR031649 GPHH_dom
IPR005821 Ion_trans_dom
IPR014873 VDCC_a1su_IQ
IPR005451 VDCC_L_a1csu
IPR005446 VDCC_L_a1su
IPR002077 VDCCAlpha1
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF08763 Ca_chan_IQ, 1 hit
PF16885 CAC1F_C, 2 hits
PF16905 GPHH, 1 hit
PF00520 Ion_trans, 4 hits
PRINTSiPR00167 CACHANNEL
PR01630 LVDCCALPHA1
PR01635 LVDCCALPHA1C
SMARTiView protein in SMART
SM01062 Ca_chan_IQ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2I3SCM5_PANTR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2I3SCM5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: June 5, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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