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Protein

RBR-type E3 ubiquitin transferase

Gene

RNF217

Organism
Pan troglodytes (Chimpanzee)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
RBR-type E3 ubiquitin transferaseSAAS annotation (EC:2.3.2.31SAAS annotation)
Gene namesi
Name:RNF217Imported
OrganismiPan troglodytes (Chimpanzee)Imported
Taxonomic identifieri9598 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000002277 Componenti: Chromosome 6

Organism-specific databases

VGNCiVGNC:11213 RNF217

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei499 – 528HelicalSequence analysisAdd BLAST30

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini328 – 396IBR-typeInterPro annotationAdd BLAST69
Domaini403 – 474IBR-typeInterPro annotationAdd BLAST72

Sequence similaritiesi

Belongs to the RBR family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis, Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00730000111285
KOiK11977

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR031127 E3_UB_ligase_RBR
IPR002867 IBR_dom
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR11685 PTHR11685, 1 hit
PfamiView protein in Pfam
PF01485 IBR, 2 hits
SMARTiView protein in SMART
SM00647 IBR, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A2I3S1Z9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGEEQSTVSG GGGPQESQTL ASGTAGHPEP PRPQGDSARA PPLRAASAEP
60 70 80 90 100
SSGGCGSDWG CADTSAPEPA RSLGPPGWSK SRAPAQPAGL ALTGPLNPQT
110 120 130 140 150
LPLQLELEEE EEEAGDGKEG GDEQQEAPPG EELEPRTRAG AADGLVLDVL
160 170 180 190 200
GQRRPPLAKR QVFCSVYCVE SDLPEAPASE QLSPPASPPG APPVLNPPSS
210 220 230 240 250
RSSFPSPRLS LPKDSLSPDG GSIELEFYLA PEPFSMPSLL GAPTYSGLGG
260 270 280 290 300
VGDPYAPLMV LMCRVCLEDK PIKPLPCCKK AVCEECLKVY LSAQVQLGQV
310 320 330 340 350
EIKCPITECF EFLEETTVVY NLTHEDSIKY KYFLELGRID SSTKPCPQCK
360 370 380 390 400
HFTTFKKKGH IPTPSRSESK YKIQCPTCQF VWCFKCHSPW HEGVNCKEYK
410 420 430 440 450
KGDKLLRHWA SEIEHGQRNA QKCPKCKIHI QRTEGCDHMT CSQCNTNFCY
460 470 480 490 500
RCGERYRQLR FFGDHTSNLS IFGCKYRYLP ERPHLRRLVR GSVCAGKLFI
510 520 530 540
APLIMVLGLA LGAIAVVIGL FVFPIYCLCK KQRKRSRTGM HW
Length:542
Mass (Da):59,274
Last modified:February 28, 2018 - v1
Checksum:iB193794445EAF4BC
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H2QTP3H2QTP3_PANTR
RBR-type E3 ubiquitin transferase
RNF217
274Annotation score:
A0A2I3TE85A0A2I3TE85_PANTR
RBR-type E3 ubiquitin transferase
RNF217
305Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04054397 Genomic DNA No translation available.
AACZ04054398 Genomic DNA No translation available.
AACZ04054399 Genomic DNA No translation available.
RefSeqiXP_518723.5, XM_518723.5

Genome annotation databases

EnsembliENSPTRT00000098781; ENSPTRP00000071012; ENSPTRG00000018571
GeneIDi462979
KEGGiptr:462979

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AACZ04054397 Genomic DNA No translation available.
AACZ04054398 Genomic DNA No translation available.
AACZ04054399 Genomic DNA No translation available.
RefSeqiXP_518723.5, XM_518723.5

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPTRT00000098781; ENSPTRP00000071012; ENSPTRG00000018571
GeneIDi462979
KEGGiptr:462979

Organism-specific databases

CTDi154214
VGNCiVGNC:11213 RNF217

Phylogenomic databases

GeneTreeiENSGT00730000111285
KOiK11977

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR031127 E3_UB_ligase_RBR
IPR002867 IBR_dom
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR11685 PTHR11685, 1 hit
PfamiView protein in Pfam
PF01485 IBR, 2 hits
SMARTiView protein in SMART
SM00647 IBR, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2I3S1Z9_PANTR
AccessioniPrimary (citable) accession number: A0A2I3S1Z9
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: June 20, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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