UniProtKB - A0A2I3RBW2 (A0A2I3RBW2_PANTR)
Protein
Submitted name:
CD200 molecule
Gene
CD200
Organism
Pan troglodytes (Chimpanzee)
Status
Functioni
GO - Biological processi
- heterotypic cell-cell adhesion Source: Ensembl
- negative regulation of macrophage activation Source: InterPro
- negative regulation of matrix metallopeptidase secretion Source: Ensembl
- negative regulation of NF-kappaB transcription factor activity Source: Ensembl
- positive regulation of arginase activity Source: Ensembl
- positive regulation of CREB transcription factor activity Source: Ensembl
- positive regulation of protein-glutamine gamma-glutamyltransferase activity Source: Ensembl
- positive regulation of transforming growth factor beta production Source: Ensembl
- regulation of immune response Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: CD200 moleculeImported |
Gene namesi | Name:CD200Imported |
Organismi | Pan troglodytes (Chimpanzee)Imported |
Taxonomic identifieri | 9598 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Pan |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:1764, CD200 |
Subcellular locationi
Other locations
- axon Source: Ensembl
- cell surface Source: Ensembl
- neuronal cell body Source: Ensembl
Family & Domainsi
Phylogenomic databases
GeneTreei | ENSGT00530000063970 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR033321, CD200 IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set IPR013151, Immunoglobulin |
PANTHERi | PTHR46841:SF3, PTHR46841:SF3, 1 hit |
Pfami | View protein in Pfam PF00047, ig, 2 hits |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
A0A2I3RBW2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MERLTLTRTI GGPLLTATLL GKTTINDYQV IRMPFCHLST YSLVWVMAAV
60 70 80 90 100
VLCTAQVQVV TQDEREQLYT PASLKCSLQN AQEALIVTWQ KKKAVSPENM
110 120 130 140 150
VTFSENHGVV IQPAYKDKIN ITQLGLQNST ITFWNITLED EGCYMCLFNT
160 170 180 190 200
FGFGKISGTA CLTVYVQPIV SLHYKFSEDH LNITCSATAR PAPMVFWKVP
210 220 230 240 250
RSGIENSTVT LSHPNGTTSV TSILHIKDPK NQVGKEVICQ VLHLGTVTDF
260 270 280 290
KQTVNKGYWF SVPLLLSIVS LVILLVLISI LLYWKRHRNQ DREP
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH2R2B6 | H2R2B6_PANTR | CD200 molecule | CD200 | 269 | Annotation score: | ||
A0A2I3S4J6 | A0A2I3S4J6_PANTR | CD200 molecule | CD200 | 286 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AACZ04048072 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSPTRT00000111351; ENSPTRP00000062157; ENSPTRG00000015217 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AACZ04048072 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSPTRT00000111351; ENSPTRP00000062157; ENSPTRG00000015217 |
Organism-specific databases
VGNCi | VGNC:1764, CD200 |
Phylogenomic databases
GeneTreei | ENSGT00530000063970 |
Family and domain databases
Gene3Di | 2.60.40.10, 2 hits |
InterProi | View protein in InterPro IPR033321, CD200 IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003599, Ig_sub IPR013106, Ig_V-set IPR013151, Immunoglobulin |
PANTHERi | PTHR46841:SF3, PTHR46841:SF3, 1 hit |
Pfami | View protein in Pfam PF00047, ig, 2 hits |
SMARTi | View protein in SMART SM00409, IG, 1 hit SM00406, IGv, 1 hit |
SUPFAMi | SSF48726, SSF48726, 2 hits |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A2I3RBW2_PANTR | |
Accessioni | A0A2I3RBW2Primary (citable) accession number: A0A2I3RBW2 Secondary accession number(s): A0A2J8MX70 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | February 28, 2018 |
Last sequence update: | February 28, 2018 | |
Last modified: | December 2, 2020 | |
This is version 12 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |