Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Non-specific serine/threonine protein kinase

Gene

PAK4

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesi
Name:PAK4Imported
OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
Taxonomic identifieri61853 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHylobatidaeNomascus
Proteomesi
  • UP000001073 Componenti: Chromosome 17

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 24CRIBInterPro annotationAdd BLAST14
Domaini172 – 423Protein kinaseInterPro annotationAdd BLAST252

Phylogenomic databases

GeneTreeiENSGT00930000150829

Family and domain databases

CDDicd01093 CRIB_PAK_like, 1 hit
Gene3Di3.90.810.10, 1 hit
InterProiView protein in InterPro
IPR000095 CRIB_dom
IPR036936 CRIB_dom_sf
IPR011009 Kinase-like_dom_sf
IPR033923 PAK_BD
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00786 PBD, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00285 PBD, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50108 CRIB, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2I3HHJ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFGKRKKRVE ISAPSNFEHR VHTGFDQHEQ KFTGLPRQWQ SLIEESARRP
60 70 80 90 100
KPLIDPACIT SIQPGAPKGE PHDVAPNGPS AGSLAVPQSS SSSSSRPPTR
110 120 130 140 150
ARGAPSPGVL GPHASEPQLA PPARTPAAPA APAVPGPPGP RSPQREPQRV
160 170 180 190 200
SHEQFRAALQ LVVDPGDPRS YLDNFIKIGE GSTGIVCIAT VRSSGKLVAV
210 220 230 240 250
KKMDLRKQQR RELLFNEVVI MRDYQHENVV EMYNSYLVGD ELWVVMEFLE
260 270 280 290 300
GGALTDIVTH TRMNEEQIAA VCLAVLQALS VLHAQGVIHR DIKSDSILLT
310 320 330 340 350
HDGRVKLSDF GFCAQVSKEV PRRKSLVGTP YWMAPELISR LPYGPEVDIW
360 370 380 390 400
SLGIMVIEMV DGEPPYFNEP PLKAMKMIRD NLPPRLKNLH KVSPSLKGFL
410 420 430 440
DRLLVRDPAQ RATAAELLKH PFLAKAGPPA SIVPLMRQNR TR
Length:442
Mass (Da):48,677
Last modified:February 28, 2018 - v1
Checksum:i18AB1D5EDB3FD869
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G1RWR4G1RWR4_NOMLE
Non-specific serine/threonine prote...
PAK4
595Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01060172 Genomic DNA No translation available.
ADFV01060173 Genomic DNA No translation available.
ADFV01060174 Genomic DNA No translation available.
ADFV01060175 Genomic DNA No translation available.
ADFV01060176 Genomic DNA No translation available.
ADFV01060177 Genomic DNA No translation available.
ADFV01060178 Genomic DNA No translation available.
ADFV01060179 Genomic DNA No translation available.
ADFV01060180 Genomic DNA No translation available.
RefSeqiXP_004091034.1, XM_004090986.2

Genome annotation databases

EnsembliENSNLET00000048317; ENSNLEP00000043074; ENSNLEG00000014517
GeneIDi100597455

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01060172 Genomic DNA No translation available.
ADFV01060173 Genomic DNA No translation available.
ADFV01060174 Genomic DNA No translation available.
ADFV01060175 Genomic DNA No translation available.
ADFV01060176 Genomic DNA No translation available.
ADFV01060177 Genomic DNA No translation available.
ADFV01060178 Genomic DNA No translation available.
ADFV01060179 Genomic DNA No translation available.
ADFV01060180 Genomic DNA No translation available.
RefSeqiXP_004091034.1, XM_004090986.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSNLET00000048317; ENSNLEP00000043074; ENSNLEG00000014517
GeneIDi100597455

Organism-specific databases

CTDi10298

Phylogenomic databases

GeneTreeiENSGT00930000150829

Family and domain databases

CDDicd01093 CRIB_PAK_like, 1 hit
Gene3Di3.90.810.10, 1 hit
InterProiView protein in InterPro
IPR000095 CRIB_dom
IPR036936 CRIB_dom_sf
IPR011009 Kinase-like_dom_sf
IPR033923 PAK_BD
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00786 PBD, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00285 PBD, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50108 CRIB, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2I3HHJ7_NOMLE
AccessioniPrimary (citable) accession number: A0A2I3HHJ7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: November 7, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again