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UniProtKB - A0A2I3GDK1 (A0A2I3GDK1_NOMLE)

Entry version 14 (02 Dec 2020)
Sequence version 1 (28 Feb 2018)
Previous versions | rss
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Protein
Submitted name:

Uncharacterized protein

Gene

CSMD1

Organism
Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CSMD1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri61853 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hylobatidae › Nomascus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001073 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3488 – 3509HelicalSequence analysisAdd BLAST22

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26Sequence analysisAdd BLAST26
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501411994927 – 3564Sequence analysisAdd BLAST3538

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi553 ↔ 580PROSITE-ProRule annotation
Disulfide bondi899 ↔ 926PROSITE-ProRule annotation
Disulfide bondi1277 ↔ 1304PROSITE-ProRule annotation
Disulfide bondi2648 ↔ 2675PROSITE-ProRule annotation
Disulfide bondi2706 ↔ 2733PROSITE-ProRule annotation
Disulfide bondi2764 ↔ 2791PROSITE-ProRule annotation
Disulfide bondi2827 ↔ 2854PROSITE-ProRule annotation
Disulfide bondi2885 ↔ 2912PROSITE-ProRule annotation
Disulfide bondi2946 ↔ 2973PROSITE-ProRule annotation
Disulfide bondi3005 ↔ 3032PROSITE-ProRule annotation
Disulfide bondi3123 ↔ 3150PROSITE-ProRule annotation
Disulfide bondi3181 ↔ 3208PROSITE-ProRule annotation
Disulfide bondi3243 ↔ 3270PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini32 – 140CUBInterPro annotationAdd BLAST109
Domaini143 – 204SushiInterPro annotationAdd BLAST62
Domaini208 – 312CUBInterPro annotationAdd BLAST105
Domaini347 – 408SushiInterPro annotationAdd BLAST62
Domaini411 – 522CUBInterPro annotationAdd BLAST112
Domaini525 – 582SushiInterPro annotationAdd BLAST58
Domaini584 – 692CUBInterPro annotationAdd BLAST109
Domaini695 – 756SushiInterPro annotationAdd BLAST62
Domaini758 – 866CUBInterPro annotationAdd BLAST109
Domaini871 – 928SushiInterPro annotationAdd BLAST58
Domaini930 – 1040CUBInterPro annotationAdd BLAST111
Domaini1043 – 1102SushiInterPro annotationAdd BLAST60
Domaini1104 – 1212CUBInterPro annotationAdd BLAST109
Domaini1215 – 1275SushiInterPro annotationAdd BLAST61
Domaini1277 – 1386CUBInterPro annotationAdd BLAST110
Domaini1389 – 1449SushiInterPro annotationAdd BLAST61
Domaini1451 – 1559CUBInterPro annotationAdd BLAST109
Domaini1562 – 1623SushiInterPro annotationAdd BLAST62
Domaini1625 – 1733CUBInterPro annotationAdd BLAST109
Domaini1739 – 1800SushiInterPro annotationAdd BLAST62
Domaini1802 – 1910CUBInterPro annotationAdd BLAST109
Domaini1913 – 1972SushiInterPro annotationAdd BLAST60
Domaini1974 – 2082CUBInterPro annotationAdd BLAST109
Domaini2085 – 2144SushiInterPro annotationAdd BLAST60
Domaini2146 – 2257CUBInterPro annotationAdd BLAST112
Domaini2256 – 2317SushiInterPro annotationAdd BLAST62
Domaini2319 – 2430CUBInterPro annotationAdd BLAST112
Domaini2430 – 2492SushiInterPro annotationAdd BLAST63
Domaini2493 – 2554SushiInterPro annotationAdd BLAST62
Domaini2555 – 2619SushiInterPro annotationAdd BLAST65
Domaini2620 – 2677SushiInterPro annotationAdd BLAST58
Domaini2678 – 2735SushiInterPro annotationAdd BLAST58
Domaini2736 – 2793SushiInterPro annotationAdd BLAST58
Domaini2794 – 2856SushiInterPro annotationAdd BLAST63
Domaini2857 – 2914SushiInterPro annotationAdd BLAST58
Domaini2918 – 2975SushiInterPro annotationAdd BLAST58
Domaini2976 – 3034SushiInterPro annotationAdd BLAST59
Domaini3035 – 3094SushiInterPro annotationAdd BLAST60
Domaini3095 – 3152SushiInterPro annotationAdd BLAST58
Domaini3153 – 3210SushiInterPro annotationAdd BLAST58
Domaini3214 – 3272SushiInterPro annotationAdd BLAST59
Domaini3273 – 3332SushiInterPro annotationAdd BLAST60

Keywords - Domaini

SignalSequence analysis, SushiPROSITE-ProRule annotationARBA annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155701

Database of Orthologous Groups

More...OrthoDBi		2377at2759

Family and domain databases

Conserved Domains Database

More...CDDi		cd00033, CCP, 28 hits
cd00041, CUB, 14 hits

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.60.120.290, 14 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000859, CUB_dom
IPR035914, Sperma_CUB_dom_sf
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00431, CUB, 14 hits
PF00084, Sushi, 28 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00032, CCP, 28 hits
SM00042, CUB, 14 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49854, SSF49854, 14 hits
SSF57535, SSF57535, 28 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01180, CUB, 14 hits
PS50923, SUSHI, 28 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A2I3GDK1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAWRRFQSL LLLLGLLVLC ARLLTAAKGQ NCGGLVQGPN GTIESPGFPH 
        60         70         80         90        100
GYPNYANCTW IIITGERNRI QLSFHTFALE EDFDILSVYD GQPQQGNLKV 
       110        120        130        140        150
RLSGFQLPSS IVSTGSILTL WFTTDFAVSA QGFKALYEVL PSHTCGNPGE 
       160        170        180        190        200
ILKGVLHGTR FNIGDKIRYS CLSGYILEGH AVLTCIVSPG NGASWDFPAP 
       210        220        230        240        250
FCRAEGACGG TLRGTISSIS SPHFPSEYEN NADCTWTIVA EPGDTIALVF 
       260        270        280        290        300
TDFQLEEGYD FLEISGTEAP SIWLTGMNLP SPVISSKNWL RLHFTSDSNH 
       310        320        330        340        350
RRKGFNAQFQ VKKAIELKSR GVKMLPSKDG SHKNSVLSQG GVALVSDMCP 
       360        370        380        390        400
DPGIPENGRR AGSDFRVGAN VQFSCEDNYV LQGSKSITCQ RVTETLAAWS 
       410        420        430        440        450
DHRPICRART CGSNLRGPSG VITSPNYPVQ YEDNAHCVWV ITTSDPDKVI 
       460        470        480        490        500
KLAFEEFELE RGYDTLTVGD AGKVGDTRSV LYVLTGSSVP DLIVSMSNQM 
       510        520        530        540        550
WLHLQSDDSI GSPGFKAVYQ EIEKGGCGDP GIPAYGKRTG SSFLHGDTLT 
       560        570        580        590        600
FECPAAFELV GERVITCQQN NQWSGNKPSC VFSCFFNFTA SSGIILSPNY 
       610        620        630        640        650
PEEYGNNMNC VWLIISEPGS RIHLIFNDFD VEPQFDFLAV KDDGISDITV 
       660        670        680        690        700
LGTFSGNEVP SQLASSGHIV RLEFQSDHST TGRGFNITYT TFGQNECHDP 
       710        720        730        740        750
GIPINGRRFG DRFLLGSSVS FHCDDGFVKT QGSESITCIL QDGNVVWSST 
       760        770        780        790        800
VPRCEAPCGG HLTASSGVIL PPGWPGYYKD SLNCEWIIEA KPGHSIKITF 
       810        820        830        840        850
DRFQTEVNYD TLEVRDGPAS SSPLIGEYHG TQAPQFLIST GNFMYLLFTT 
       860        870        880        890        900
DNSRSSIGFL IHYESVTLES DSCLDPGIPV NGHRHGGDFG IRSTVTFSCD 
       910        920        930        940        950
PGYTLSDDEP LVCERNHQWN HALPSCDALC GGYIQGKTGT VLSPGFPDFY 
       960        970        980        990       1000
PNSLNCTWTI EVSHGKGVQM IFHTFHLESS HDYLLITEDG SFSEPVARLT 
      1010       1020       1030       1040       1050
GSVLPHTIKA GLFGNFTAQL RFISDFSISY EGFNITFSEY DLEPCDDPGV 
      1060       1070       1080       1090       1100
PAFSRRIGFQ FGVGDSLTFS CFPGYRLEGA TKLTCLGGGR RVWSAPLPRC 
      1110       1120       1130       1140       1150
VAECGASVKG NEGTLLSPNF PSNYDNNHEC IYKIETEAGK GIHLRARSFQ 
      1160       1170       1180       1190       1200
LFEGDTLKVY DGKDSSSRPL GTFTKNELLG LILNSTSNHL WLEFNTNGSD 
      1210       1220       1230       1240       1250
TNQGFQLTYT SFELVKCEDP GIPNYGYRIR DEGHFTDTVV LYSCNPGYAM 
      1260       1270       1280       1290       1300
HGSNTLTCLS GDRRVWDKPL PSCIAECGGQ IHAATSGRIL SPGYPAPYDN 
      1310       1320       1330       1340       1350
NLHCTWIIEA DPGKTISLHF IVFDTETAHD ILKVWDGPVG SNILLKEWSG 
      1360       1370       1380       1390       1400
SALPEDIHST FNSLTLQFDS DFFISKSGFS IQFSTSIAAT CNDPGMPQNG 
      1410       1420       1430       1440       1450
TRYGDSREAG DTVTFQCDPG YQLQGQAKIT CVQLNNRFFW QPDPPTCIAA 
      1460       1470       1480       1490       1500
CGGNLTGPAG VILSPNYPQP YPPGKECDWR VKVNPDFVIA LIFKSFNMEP 
      1510       1520       1530       1540       1550
SYDFLHIYEG EDSNSPLIGS YQGSQAPERV ESSGNSLFLA FRSDASVGLS 
      1560       1570       1580       1590       1600
GFAIEFKEKP REACFDPGNI MNGTRIGTDF KLGSTVTYQC DSGYKIVDPS 
      1610       1620       1630       1640       1650
SITCVIGADG KPSWDQVLPS CNAPCGGQYT GSEGVVLSPN YPHNYTAGEV 
      1660       1670       1680       1690       1700
CIYYITVPKE FVVFGQFAYF QTALNDLAEL FDGTHAQARL LSSLSGSHSG 
      1710       1720       1730       1740       1750
ETLPLATSNQ ILLRFSAKSG ASARGFHFVY QAVPRTSDTQ CSSVPEPRYG 
      1760       1770       1780       1790       1800
RRIGSEFSAG SIVRFECNPG YLLQGSTALH CQSVPNALAQ WNDTIPSCVV 
      1810       1820       1830       1840       1850
PCSGNFTQRR GTILSPGYPE PYGNNLNCIW KIIVTEGSGI QIQVISFATE 
      1860       1870       1880       1890       1900
QNWDSLEIHD GGDVTAPRLG SFSGTTVPAL LNSTSNQLYL HFQSDISVAA 
      1910       1920       1930       1940       1950
AGFHLEYKTV GLAACQEPAL PSNSIKIGDR YMVNDVLSFQ CEPGYTLQGR 
      1960       1970       1980       1990       2000
SHISCMPGTV RRWNYPSPLC IATCGGTLST LGGVILSPGF PGSYPNNLDC 
      2010       2020       2030       2040       2050
TWRISLPIGY GAHIQFLNFS TEANHDFLEI QNGPYHTSPM IGQFSGTDLP 
      2060       2070       2080       2090       2100
AALLSTTHET LIHFYSDHSQ NRQGFKLAYQ AYELQNCPDP PPFQNGYMIN 
      2110       2120       2130       2140       2150
SDYSVGQSIS FECYPGYILI GHPVLTCQHG INRNWNYPFP RCDAPCGYNV 
      2160       2170       2180       2190       2200
TSQNGTIYSP GFPDEYPILK DCIWLITVPP GHGVYINFTL LQTEAVNDYI 
      2210       2220       2230       2240       2250
AVWDGPDQNS PQLGVFSGNT ALETAYSSSN QVLLKFHSDF SNGGFFVLNF 
      2260       2270       2280       2290       2300
HAFQLKKCQP PPAVPQAEML TEDDDFEIGD FVKYQCHPGY TLVGTDTLTC 
      2310       2320       2330       2340       2350
KLSSQLQFEG SLPTCEAQCP ANEVRTGSSG VILSPGYPGN YFNSQTCSWS 
      2360       2370       2380       2390       2400
IKVEPNYNIT IFVDTFQSEK QFDALEVFDG SSGQSPLLVV LSGNHTEQSN 
      2410       2420       2430       2440       2450
FTSRSNQLYL RWSADHATSK KGFKIRYAAP YCSLTHTLKN GGILNRTAGA 
      2460       2470       2480       2490       2500
VGSKVHYFCK PGYRMIGHSN ATCRRNPLGM YQWDSLMPVC QAVSCGIPEA 
      2510       2520       2530       2540       2550
PGNGSFTGNE FTLDSKVVYE CHEGFKLESS QQATAVCQED GLWSNKGKPP 
      2560       2570       2580       2590       2600
TCKPVPCPSI EAQLSEHVIW RLVSGSLNEY GAQVLLSCSP GYYLEGRRLV 
      2610       2620       2630       2640       2650
QCQANGTWNI GDERPSCRVI SCGSLSFPPN GNKIGTLTVY GATAIFTCNT 
      2660       2670       2680       2690       2700
GYTLVGSHVR ECLANGLWSG TETRCLAGHC GSPDPIVNGH ISGDGFSYRD 
      2710       2720       2730       2740       2750
TVVYQCNPGF RLVGTSVRIC LQDHKWSGQT PVCVPITCGH PGNPAHGFTN 
      2760       2770       2780       2790       2800
GSEFNLNDVV NFTCNTGYLL QGVSGAQCRS NGQWSSPLPT CRVVNCSDPG 
      2810       2820       2830       2840       2850
FVENAIRQGQ QNFPESFEYG MSVLYHCKKG FYLLGSSVLT CMANGLWDRS 
      2860       2870       2880       2890       2900
LPKCLAISCG HPGVPANAVL TGELFTYGAI VRYSCRGSQT LVGNDTRVCQ 
      2910       2920       2930       2940       2950
GDSHWSGALP HCTGNNPGFC GDPGTPAHGS RLGDEFKTKS LLRFSCEMGH 
      2960       2970       2980       2990       3000
QLRGSPERTC LLNGSWSGLQ PVCEAVSCGN PGTPTNGMIV SSDGILFSSS 
      3010       3020       3030       3040       3050
VIYACWEGYK TSGLMTRHCT ANGTWTGTAP DCTIISCGDP GTLANGIQFG 
      3060       3070       3080       3090       3100
NDFTFNKTVS YQCNPGYLME PVTSATIRCT KDGTWNQSKP VCKAVLCPQP 
      3110       3120       3130       3140       3150
PPVPNGTVEG TDFRWGSSIS YSCVDGYQLS HSAILSCEGR GVWKGEIPQC 
      3160       3170       3180       3190       3200
LPVFCGDPGI PAEGRLSGKS FTYKSEVFFQ CKSPFILVGS SRRICQADGM 
      3210       3220       3230       3240       3250
WSGMQPTCVD PAHNNCPDPG TPHFGIQNSS RGYEVGSTVF FRCRKGYHIQ 
      3260       3270       3280       3290       3300
GSTTRTCLAN LTWSGTQTAC IPHACRQPET PAHADVRAID LPTFGYTLVY 
      3310       3320       3330       3340       3350
TCHPGFFLAG GSEHRTCKAD MRWTGKSPVC KSKGVREVNE TVTKTPVPSD 
      3360       3370       3380       3390       3400
VFFVNSVWKG YYEYLGKRQP ATLTVDWFNA TSSKVNATFS EASPVELKLT 
      3410       3420       3430       3440       3450
GVYKKEEAHL LLKSFQIKGQ ADIFVSKFEN DNWGLDGYVS SGLERGGFTF 
      3460       3470       3480       3490       3500
QGDIHGKDFG KFKLERQDPL NPDQDSSNHY HGTSSGSVAA AILVPFFALI 
      3510       3520       3530       3540       3550
LSGFAFYLYK HRTRPKVQYN GYAGHENSNG QASFENPMYD TNLKPTEAKA 
      3560 
VRFDTTLNTV CTVV
Length:3,564
Mass (Da):388,443
Last modified:February 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i00E383DB9703C70D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3H2P7A0A2I3H2P7_NOMLE
Uncharacterized protein
CSMD1
3,565Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G1RXZ2G1RXZ2_NOMLE
Uncharacterized protein
CSMD1
3,266Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
ADFV01065515 Genomic DNA No translation available.
ADFV01065516 Genomic DNA No translation available.
ADFV01065517 Genomic DNA No translation available.
ADFV01065518 Genomic DNA No translation available.
ADFV01065519 Genomic DNA No translation available.
ADFV01065520 Genomic DNA No translation available.
ADFV01065521 Genomic DNA No translation available.
ADFV01065522 Genomic DNA No translation available.
ADFV01065523 Genomic DNA No translation available.
ADFV01065524 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		XP_003271454.1, XM_003271406.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSNLET00000055588; ENSNLEP00000029377; ENSNLEG00000014886

Database of genes from NCBI RefSeq genomes

More...GeneIDi		100590208

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		nle:100590208

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ADFV01065515 Genomic DNA No translation available.
ADFV01065516 Genomic DNA No translation available.
ADFV01065517 Genomic DNA No translation available.
ADFV01065518 Genomic DNA No translation available.
ADFV01065519 Genomic DNA No translation available.
ADFV01065520 Genomic DNA No translation available.
ADFV01065521 Genomic DNA No translation available.
ADFV01065522 Genomic DNA No translation available.
ADFV01065523 Genomic DNA No translation available.
ADFV01065524 Genomic DNA No translation available.
RefSeqiXP_003271454.1, XM_003271406.3

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

EnsembliENSNLET00000055588; ENSNLEP00000029377; ENSNLEG00000014886
GeneIDi100590208
KEGGinle:100590208

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		64478

Phylogenomic databases

GeneTreeiENSGT00940000155701
OrthoDBi2377at2759

Family and domain databases

CDDicd00033, CCP, 28 hits
cd00041, CUB, 14 hits
Gene3Di2.60.120.290, 14 hits
InterProiView protein in InterPro
IPR000859, CUB_dom
IPR035914, Sperma_CUB_dom_sf
IPR035976, Sushi/SCR/CCP_sf
IPR000436, Sushi_SCR_CCP_dom
PfamiView protein in Pfam
PF00431, CUB, 14 hits
PF00084, Sushi, 28 hits
SMARTiView protein in SMART
SM00032, CCP, 28 hits
SM00042, CUB, 14 hits
SUPFAMiSSF49854, SSF49854, 14 hits
SSF57535, SSF57535, 28 hits
PROSITEiView protein in PROSITE
PS01180, CUB, 14 hits
PS50923, SUSHI, 28 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2I3GDK1_NOMLE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2I3GDK1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: December 2, 2020
This is version 14 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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