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Protein

S-formylglutathione hydrolase

Gene
N/A
Organism
Gorilla gorilla gorilla (Western lowland gorilla)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Serine hydrolase involved in the detoxification of formaldehyde.UniRule annotation

Catalytic activityi

S-formylglutathione + H2O = glutathione + formate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Serine esteraseUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
S-formylglutathione hydrolaseUniRule annotation (EC:3.1.2.12UniRule annotation)
OrganismiGorilla gorilla gorilla (Western lowland gorilla)Imported
Taxonomic identifieri9595 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeGorilla
Proteomesi
  • UP000001519 Componenti: Chromosome 13

Subcellular locationi

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

SMRiA0A2I2Z6U1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the esterase D family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000011864
KOiK01070

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000801 Esterase_put
IPR014186 S-formylglutathione_hydrol
PANTHERiPTHR10061 PTHR10061, 1 hit
PfamiView protein in Pfam
PF00756 Esterase, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit
TIGRFAMsiTIGR02821 fghA_ester_D, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2I2Z6U1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKFAVYLPPK AETGKCPALY WLSGLTCTEQ NFISKSGYHQ SASEHGLVVI
60 70 80 90 100
APDTSPRGCN IKGEDESWDF GTGAGFYVDA TEDPWKTNYR MYSYVTEELP
110 120 130 140 150
QLINANFPVD PQRMSIFGHS MGGHGALICA LKNPGKYKSV SAFAPICNPV
160 170 180 190 200
LCPWGKKAFS GYLGTDQSKW KAYDATHLVK SYPGSQLDIL IDQGKDDQFL
210 220 230 240 250
LDGQLLPDNF IAACTEKKIP VVFRLQEGYD HSYYFIATFI TDHIRHHAKY

LNA
Length:253
Mass (Da):28,226
Last modified:February 28, 2018 - v1
Checksum:i502E8BE6D8178FEF
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I2ZKH8A0A2I2ZKH8_GORGO
S-formylglutathione hydrolase
274Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030088911 Genomic DNA No translation available.
RefSeqiXP_004054534.2, XM_004054486.2

Genome annotation databases

EnsembliENSGGOT00000066851; ENSGGOP00000042963; ENSGGOG00000041798
GeneIDi101127827
KEGGiggo:101127827

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CABD030088911 Genomic DNA No translation available.
RefSeqiXP_004054534.2, XM_004054486.2

3D structure databases

SMRiA0A2I2Z6U1
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGGOT00000066851; ENSGGOP00000042963; ENSGGOG00000041798
GeneIDi101127827
KEGGiggo:101127827

Organism-specific databases

CTDi2098

Phylogenomic databases

GeneTreeiENSGT00390000011864
KOiK01070

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000801 Esterase_put
IPR014186 S-formylglutathione_hydrol
PANTHERiPTHR10061 PTHR10061, 1 hit
PfamiView protein in Pfam
PF00756 Esterase, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit
TIGRFAMsiTIGR02821 fghA_ester_D, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2I2Z6U1_GORGO
AccessioniPrimary (citable) accession number: A0A2I2Z6U1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: October 10, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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