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Protein
Submitted name:

Uncharacterized protein

Gene

ABCB1

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi430 – 437ATPPROSITE-ProRule annotation8
Nucleotide bindingi1073 – 1080ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:ABCB1Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)Imported
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
Proteomesi
  • UP000011712 Componenti: Chromosome A2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei51 – 74HelicalSequence analysisAdd BLAST24
Transmembranei118 – 142HelicalSequence analysisAdd BLAST25
Transmembranei193 – 211HelicalSequence analysisAdd BLAST19
Transmembranei217 – 236HelicalSequence analysisAdd BLAST20
Transmembranei296 – 319HelicalSequence analysisAdd BLAST24
Transmembranei711 – 737HelicalSequence analysisAdd BLAST27
Transmembranei757 – 780HelicalSequence analysisAdd BLAST24
Transmembranei862 – 882HelicalSequence analysisAdd BLAST21
Transmembranei938 – 957HelicalSequence analysisAdd BLAST20
Transmembranei977 – 998HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 360ABC transmembrane type-1InterPro annotationAdd BLAST307
Domaini395 – 631ABC transporterInterPro annotationAdd BLAST237
Domaini715 – 1003ABC transmembrane type-1InterPro annotationAdd BLAST289
Domaini1038 – 1276ABC transporterInterPro annotationAdd BLAST239

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili270 – 290Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00530000062896

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030258 MDR1
IPR027417 P-loop_NTPase
IPR039421 Type_I_exporter
PANTHERiPTHR24221 PTHR24221, 1 hit
PTHR24221:SF251 PTHR24221:SF251, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A2I2UEG7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVAMDLEGGS NGRAEKKFWK MGEKSKKEKK EKKPTVSTLA MFRYSNWLDR
60 70 80 90 100
FYMLVGTVAA IIHGAALPLM MLVFGDMTDS FANAGISRNL TTLNITGESI
110 120 130 140 150
VNDSYFINRL EEEMTTYAYY YSGIGAGVLV AAYIQVSFWC LAAGRQILKI
160 170 180 190 200
RKQFFHAIMR QEVGWFDVHD VGELNTRLTD DVSKINEGIG DKIGMFFQSL
210 220 230 240 250
ATFFIGFIVG FTRGWKLTLV ILAISPVLGL SAAIWAKILS SFTDKELLAY
260 270 280 290 300
AKAGAVAEEV LAAIRTVIAF GGQKKELERY NKNLEEAKRI GIKKAITANI
310 320 330 340 350
SIGIAFLLIY ASYALAFWYG TSLVLSHEYS IGQVLTVFFS VLIGAFSVGQ
360 370 380 390 400
ASPSIEAFAN ARGAAYEIFK IIDNKPSIDS YSKNGHKPDN IKGNLEFKNV
410 420 430 440 450
HFSYPSRKEV KILKGLNLKV QSGQTVALVG NSGCGKSTTV QLMQRLYDPT
460 470 480 490 500
DGMVSIDGQD IRTINVRYLR EIIGVVSQEP VLFATTIAEN ICYGRENVTM
510 520 530 540 550
EEIEKAVKEA NAYDFIMKLP NKFDTLVGER GAQLSGGQKQ RIAIARALVR
560 570 580 590 600
NPKILLLDEA TSALDSESEA VVQVALDKAR KGRTTIVVAH RLSTIRNADV
610 620 630 640 650
IAGFDDGVIV EKGNHDELMK EEGIYFKLVT MQTRGNEIEL ENAVYESISE
660 670 680 690 700
IDALEMSPKD SGSSLIRRRS TRKSIHASQG QDRKLGTKEN LDEHVPPVSF
710 720 730 740 750
WRILKLNITE WPYFVVGIFC AIINGGLQPA FSVIFSRIIG VFTRVEDPET
760 770 780 790 800
KRQNSNIFSL LFLVLGIISF ITFFLQGFTF GKAGEILTKR LRYMVFRSML
810 820 830 840 850
RQDVSWFDDP KNTTGALTTR LANDAAQVKG AIGSRLAIIT QNIANLGTGI
860 870 880 890 900
IISLIYGWQL TLLLLAIVPI IAIAGVVEMK MLSGQALKDK KELEGAGKIA
910 920 930 940 950
TEAIENFRTV VSLTREQKFE YMYAQSLQVP YRNSLRKAHI FGISFSITQA
960 970 980 990 1000
MMYFSYAGCF RFGAYLVAHE FMDFQDVLLV FSAIVFGAMA VGQVSSFAPD
1010 1020 1030 1040 1050
YAKAKVSAAH VIMIIEKIPL IDSYSTEGLM PNTLEGNVTF NEVMFNYPTR
1060 1070 1080 1090 1100
PDIPVLQGLS LEVKKGQTLA LVGSSGCGKS TVVQLLERFY DPMAGTVLID
1110 1120 1130 1140 1150
GKEIKHLNVQ WLRAHMGIVS QEPILFDCSI GENIAYGDNS RVVSQEEIVR
1160 1170 1180 1190 1200
AAKEANIHPF IETLPDKYNT RVGDKGTQLS GGQKQRIAIA RALVRQPRIL
1210 1220 1230 1240 1250
LLDEATSALD TESEKVVQEA LDKAREGRTC IVIAHRLSTI QNADLIVVFQ
1260 1270 1280
NGKVKEHGTH QQLLAQKGIY FSMVSVQAGA KR
Length:1,282
Mass (Da):141,918
Last modified:February 28, 2018 - v1
Checksum:iEED76C296521EB2E
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
M3XB77M3XB77_FELCA
Uncharacterized protein
ABCB1
1,292Annotation score:
A0A2I2UET2A0A2I2UET2_FELCA
Uncharacterized protein
ABCB1
1,279Annotation score:
A0A2I2UCK7A0A2I2UCK7_FELCA
Uncharacterized protein
ABCB1
1,219Annotation score:
A0A2I2UTT2A0A2I2UTT2_FELCA
Uncharacterized protein
ABCB1
1,253Annotation score:
A0A337SRP6A0A337SRP6_FELCA
Uncharacterized protein
ABCB1
1,215Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04003224 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSFCAT00000035358; ENSFCAP00000030907; ENSFCAG00000027959

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG04003224 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSFCAT00000035358; ENSFCAP00000030907; ENSFCAG00000027959

Phylogenomic databases

GeneTreeiENSGT00530000062896

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030258 MDR1
IPR027417 P-loop_NTPase
IPR039421 Type_I_exporter
PANTHERiPTHR24221 PTHR24221, 1 hit
PTHR24221:SF251 PTHR24221:SF251, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2I2UEG7_FELCA
AccessioniPrimary (citable) accession number: A0A2I2UEG7
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: November 7, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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