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Protein

Probable tRNA pseudouridine synthase B

Gene

truB

Organism
Euryarchaeota archaeon CG_4_9_14_3_um_filter_38_12
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei70NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotation
Biological processtRNA processingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Probable tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
ORF Names:CO114_04050Imported
OrganismiEuryarchaeota archaeon CG_4_9_14_3_um_filter_38_12Imported
Taxonomic identifieri1975559 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeota

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini236 – 311PUAInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.UniRule annotation

Family and domain databases

HAMAPiMF_01081 TruB_arch, 1 hit
InterProiView protein in InterPro
IPR012960 Dyskerin-like
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR002478 PUA
IPR015947 PUA-like_sf
IPR004802 tRNA_PsdUridine_synth_B_fam
IPR026326 TruB_arch
IPR032819 TruB_C
IPR004521 Uncharacterised_CHP00451
PANTHERiPTHR23127 PTHR23127, 1 hit
PfamiView protein in Pfam
PF08068 DKCLD, 1 hit
PF01472 PUA, 1 hit
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SMARTiView protein in SMART
SM01136 DKCLD, 1 hit
SM00359 PUA, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
SSF88697 SSF88697, 1 hit
TIGRFAMsiTIGR00425 CBF5, 1 hit
TIGR00451 unchar_dom_2, 1 hit
PROSITEiView protein in PROSITE
PS50890 PUA, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2H9QVA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIMSSPELVK SKDKTCQDFG KKPDERNMLE YINLGVINLN KPSGPTSHQV
60 70 80 90 100
VAWIKKILNI EKAGHGGTLD PRVTGVLPVA LGESTKTLKL LLSHSKEYVG
110 120 130 140 150
VMRTHKDVNE KNLRKTCSNF VGEIKQLPPV RSAVKRQVRK RKVYYLNILE
160 170 180 190 200
IQGRDALFKV GCESGTYIRT LCNDIGKKIG GAHLQELRRT KGGGFDEKDS
210 220 230 240 250
VTLQELKDAY IYWKEENNEK ELRKIIMPME KMLEGMYKIR VRDSAVDAVC
260 270 280 290 300
HGANLALPGI VSLDRDIKKD EMVAILTLKD EGVAYGKALM TSEEIMNKKN
310 320
GYAVSLQRVL MEPGTYPKCW QKH
Length:323
Mass (Da):36,432
Last modified:February 28, 2018 - v1
Checksum:i4C6AE46B7CAE8FC2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
PFUM01000173 Genomic DNA Translation: PJB21683.1

Similar proteinsi

Entry informationi

Entry nameiA0A2H9QVA0_9EURY
AccessioniPrimary (citable) accession number: A0A2H9QVA0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: April 25, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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