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Protein
Submitted name:

Glutaryl-CoA dehydrogenase

Gene

GCDH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Cofactori

FADUniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Names & Taxonomyi

Protein namesi
Submitted name:
Glutaryl-CoA dehydrogenaseImported
Gene namesi
Name:GCDHImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 172Acyl-CoA_dh_NInterPro annotationAdd BLAST111
Domaini176 – 269Acyl-CoA_dh_MInterPro annotationAdd BLAST94
Domaini289 – 428Acyl-CoA_dh_1InterPro annotationAdd BLAST140

Sequence similaritiesi

Belongs to the acyl-CoA dehydrogenase family.UniRule annotation

Family and domain databases

Gene3Di1.10.540.10, 1 hit
InterProiView protein in InterPro
IPR006089 Acyl-CoA_DH_CS
IPR006091 Acyl-CoA_Oxase/DH_cen-dom
IPR036250 AcylCo_DH-like_C
IPR009075 AcylCo_DH/oxidase_C
IPR013786 AcylCoA_DH/ox_N
IPR037069 AcylCoA_DH/ox_N_sf
IPR009100 AcylCoA_DH/oxidase_NM_dom
PfamiView protein in Pfam
PF00441 Acyl-CoA_dh_1, 1 hit
PF02770 Acyl-CoA_dh_M, 1 hit
PF02771 Acyl-CoA_dh_N, 1 hit
SUPFAMiSSF47203 SSF47203, 1 hit
SSF56645 SSF56645, 1 hit
PROSITEiView protein in PROSITE
PS00072 ACYL_COA_DH_1, 1 hit
PS00073 ACYL_COA_DH_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2H4G235-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALRGVSVRL LSRGPGLHVL RTWVSSAAQT EKGGRTQSQL AKSSRPEFDW
60 70 80 90 100
QDPLVLEEQL TTDEILIRDT FRTYCQERLM PRILLANRNE VFHREIISEM
110 120 130 140 150
GELGVLGPTI KGYGCAGVSS VAYGLLAREL ERVDSGYRSA MSVQSSLVMH
160 170 180 190 200
PIYAYGSEEQ RQKYLPQLAK GELLGCFGLT EPNSGSDPSS METRAHYNSS
210 220 230 240 250
NKSYTLNGTK TWITNSPMAD LFVVWARCED GCIRGFLLEK GMRGLSAPRI
260 270 280 290 300
QGKFSLQASA TGMIIMDGVE VPEENVLPGA SSLGGPFGCL NNARYGIAWG
310 320 330 340 350
VLGASEFCLH TARQYALDRM QFGVPLARNQ LIQKKLADML TEITLGLHAC
360 370 380 390 400
LQLGRLKDQD KAAPEMVSLL KRNNCGKALD IARQARDMLG GNGISDEYHV
410 420 430
IRHAMNLEAV NTYEGTHDIH ALILGRAITG IQAFTASK
Length:438
Mass (Da):48,099
Last modified:February 28, 2018 - v1
Checksum:iD38A5E510326F00F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KU297259 mRNA Translation: APD78595.1
KU297260 mRNA Translation: APD78596.1
KU297261 mRNA Translation: APD78597.1
UniGeneiHs.532699

Similar proteinsi

Entry informationi

Entry nameiA0A2H4G235_HUMAN
AccessioniPrimary (citable) accession number: A0A2H4G235
Entry historyiIntegrated into UniProtKB/TrEMBL: February 28, 2018
Last sequence update: February 28, 2018
Last modified: April 25, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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