Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phospho-N-acetylmuramoyl-pentapeptide-transferase

Gene

mraY

Organism
Halobacteriovorax sp. JY17
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

UDP-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala) + undecaprenyl phosphate = UMP + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol.UniRule annotation

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationImported
Biological processCell cycle, Cell divisionUniRule annotation, Cell shape, Cell wall biogenesis/degradationUniRule annotation, Peptidoglycan synthesisUniRule annotation

Enzyme and pathway databases

UniPathwayi
UPA00219

Names & Taxonomyi

Protein namesi
Recommended name:
Phospho-N-acetylmuramoyl-pentapeptide-transferaseUniRule annotation (EC:2.7.8.13UniRule annotation)
Alternative name(s):
UDP-MurNAc-pentapeptide phosphotransferaseUniRule annotation
Gene namesi
Name:mraYUniRule annotation
ORF Names:CES88_08725Imported
OrganismiHalobacteriovorax sp. JY17Imported
Taxonomic identifieri2014617 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaOligoflexiaBacteriovoracalesHalobacteriovoraceaeHalobacteriovorax
Proteomesi
  • UP000229005 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei27 – 48HelicalUniRule annotationAdd BLAST22
Transmembranei69 – 89HelicalUniRule annotationAdd BLAST21
Transmembranei95 – 114HelicalUniRule annotationAdd BLAST20
Transmembranei134 – 152HelicalUniRule annotationAdd BLAST19
Transmembranei172 – 191HelicalUniRule annotationAdd BLAST20
Transmembranei198 – 217HelicalUniRule annotationAdd BLAST20
Transmembranei237 – 254HelicalUniRule annotationAdd BLAST18
Transmembranei261 – 281HelicalUniRule annotationAdd BLAST21
Transmembranei287 – 309HelicalUniRule annotationAdd BLAST23
Transmembranei336 – 355HelicalUniRule annotationAdd BLAST20

GO - Cellular componenti

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 4 family. MraY subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Family and domain databases

CDDicd06852 GT_MraY, 1 hit
HAMAPiMF_00038 MraY, 1 hit
InterProiView protein in InterPro
IPR000715 Glycosyl_transferase_4
IPR003524 PNAcMuramoyl-5peptid_Trfase
IPR018480 PNAcMuramoyl-5peptid_Trfase_CS
PANTHERiPTHR22926 PTHR22926, 1 hit
PfamiView protein in Pfam
PF00953 Glycos_transf_4, 1 hit
PF10555 MraY_sig1, 1 hit
TIGRFAMsiTIGR00445 mraY, 1 hit
PROSITEiView protein in PROSITE
PS01347 MRAY_1, 1 hit
PS01348 MRAY_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2G8HT49-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLYHFLYPLS QDISAFNIFR YITFRTFAAF LIATIVSIIW GRFFINFMKR
60 70 80 90 100
KQFGQVVRDD GPQSHLKKAG TPTMGGVLII GTIMLSMAFC ANFMSIPVLT
110 120 130 140 150
TLSVTLSYFV LGFFDDYLKV MKKNSDGISA KGKLLWQFAT ALIAGYFLIS
160 170 180 190 200
RGVIDTSLYL PFVKGPVLDL GWYYILFIGV VVVGSSNAVN LTDGLDGLAI
210 220 230 240 250
GPIITSAASL GIIAYAAGHR EIAGYLYIPY VEDIGELMVI SAAIIGAGVG
260 270 280 290 300
FLWYNSYPAQ IFMGDVGSLS LGGTLGIVAV LTKSEVLFVI IGGIFVIEAV
310 320 330 340 350
SVILQVASYK MRKKRIFKMA PIHHHFELKG WPEPKVIVRF WIISIFLAMF

AIATLKMR
Length:358
Mass (Da):39,476
Last modified:January 31, 2018 - v1
Checksum:i1AB1DAD439202AAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NJER01000002 Genomic DNA Translation: PIK14416.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NJER01000002 Genomic DNA Translation: PIK14416.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayi
UPA00219

Family and domain databases

CDDicd06852 GT_MraY, 1 hit
HAMAPiMF_00038 MraY, 1 hit
InterProiView protein in InterPro
IPR000715 Glycosyl_transferase_4
IPR003524 PNAcMuramoyl-5peptid_Trfase
IPR018480 PNAcMuramoyl-5peptid_Trfase_CS
PANTHERiPTHR22926 PTHR22926, 1 hit
PfamiView protein in Pfam
PF00953 Glycos_transf_4, 1 hit
PF10555 MraY_sig1, 1 hit
TIGRFAMsiTIGR00445 mraY, 1 hit
PROSITEiView protein in PROSITE
PS01347 MRAY_1, 1 hit
PS01348 MRAY_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2G8HT49_9PROT
AccessioniPrimary (citable) accession number: A0A2G8HT49
Entry historyiIntegrated into UniProtKB/TrEMBL: January 31, 2018
Last sequence update: January 31, 2018
Last modified: June 20, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again