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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Acidimicrobiaceae bacterium
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei137GTPUniRule annotation1
Binding sitei141GTPUniRule annotation1
Binding sitei185GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 23GTPUniRule annotation5
Nucleotide bindingi106 – 108GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:CL445_10090Imported
OrganismiAcidimicrobiaceae bacteriumImported
Taxonomic identifieri2024894 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaAcidimicrobiiaAcidimicrobialesAcidimicrobiaceae

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 203TubulinInterPro annotationAdd BLAST193
Domaini205 – 322Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2E8Y3B3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGSPQNYLA VIKVIGVGGG GVNAVNRMID AGLRGVEFIA VNTDAQALLM
60 70 80 90 100
SDADIKLDIG RELTRGLGAG SDPDVGRGAA EAHESEITEL VKGADMVFIT
110 120 130 140 150
AGEGGGTGTG AAPVIAEIAR SVGALTIGVV TRPFAFEGRR RSVQAESGIQ
160 170 180 190 200
RLKEKVDTLI VIPNDRLLSV ANEKTXVLSA FKMADDVLLD GVSGITNLLT
210 220 230 240 250
IPGLINTDFA DVRMVLSEAG SALMGIGQAG GDERAVAAAK AAISSPLLES
260 270 280 290 300
AIDGARGVLL NITGPSSMGL FEMNAAAEII HSVAHPDVNL IFGTVIDDEM
310 320 330 340 350
GDEVKITVVA AGFDRVDSIS GVESAPATGA SRLSELFTDD ESEDEEDDGF

DVPSFLK
Length:357
Mass (Da):36,718
Last modified:January 31, 2018 - v1
Checksum:iC1D8AD7FFC0F75FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
PBWL01000066 Genomic DNA Translation: MBS32750.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
PBWL01000066 Genomic DNA Translation: MBS32750.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2E8Y3B3_9ACTN
AccessioniPrimary (citable) accession number: A0A2E8Y3B3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 31, 2018
Last sequence update: January 31, 2018
Last modified: October 10, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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