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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Massilia violaceinigra
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotationSAAS annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotationSAAS annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase (pncB)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseImported, LigaseUniRule annotationSAAS annotation, Transferase
Biological processPyridine nucleotide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotationSAAS annotation (EC:6.3.4.21UniRule annotationSAAS annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotationImported
ORF Names:CR152_19760Imported
OrganismiMassilia violaceinigraImported
Taxonomic identifieri2045208 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeMassilia
Proteomesi
  • UP000229897 Componenti: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK00763

Family and domain databases

HAMAPiMF_00570 NAPRTase, 1 hit
InterProiView protein in InterPro
IPR006406 Nic_PRibTrfase
IPR007229 Nic_PRibTrfase-Fam
IPR036068 Nicotinate_pribotase_like_C
PANTHERiPTHR11098 PTHR11098, 1 hit
PfamiView protein in Pfam
PF04095 NAPRTase, 1 hit
PIRSFiPIRSF000484 NAPRT, 1 hit
SUPFAMiSSF51690 SSF51690, 1 hit
TIGRFAMsiTIGR01514 NAPRTase, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2D2DNE6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPIVPIVHS LLETDLYKFT MWQALLHRHP AAQAEYAFTC RNQSAYPLSE
60 70 80 90 100
LKADVERELD HLCSLSFKPE EIAYLRGLRF IKSDFADFLT VFRFQRHFLS
110 120 130 140 150
VETDGDALQI RATGPQVHVM GFEIYVLYIV NELYFRRFDQ EAALAEGRKR
160 170 180 190 200
LQAKIALLRG LASEPAKRHP FEFFDFGVRR RFSGAWHEEV VATLAREVPT
210 220 230 240 250
YFKGTSNVYF AMKYKLVPIG TMAHEYLQSF QSFGVRLRDF QKAALEDWVQ
260 270 280 290 300
EYRGDLGTAL TDVVGMDAFL SDFDLYFAKL FDGLRHDSGD PVEWGEKALA
310 320 330 340 350
HYAKLRLDAH TRRLVFSDGL DLPTAFSLYR HFADRTMTGF GIGTNLSNDV
360 370 380 390
GITPLNIVMK LMSCNGQPVA KLSDSKGKTL CKDETFLAYL RQVFNHPAA
Length:399
Mass (Da):45,620
Last modified:January 31, 2018 - v1
Checksum:i48E3E04781D7F64E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP024608 Genomic DNA Translation: ATQ76506.1

Genome annotation databases

KEGGimass:CR152_19760

Similar proteinsi

Entry informationi

Entry nameiA0A2D2DNE6_9BURK
AccessioniPrimary (citable) accession number: A0A2D2DNE6
Entry historyiIntegrated into UniProtKB/TrEMBL: January 31, 2018
Last sequence update: January 31, 2018
Last modified: July 18, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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