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Protein
Submitted name:

zinc finger protein 236 isoform X2

Gene

znf236

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
zinc finger protein 236 isoform X2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:znf236Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7998 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000221080 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini33 – 61C2H2-typeInterPro annotationAdd BLAST29
Domaini62 – 89C2H2-typeInterPro annotationAdd BLAST28
Domaini89 – 116C2H2-typeInterPro annotationAdd BLAST28
Domaini117 – 144C2H2-typeInterPro annotationAdd BLAST28
Domaini149 – 176C2H2-typeInterPro annotationAdd BLAST28
Domaini195 – 222C2H2-typeInterPro annotationAdd BLAST28
Domaini223 – 250C2H2-typeInterPro annotationAdd BLAST28
Domaini251 – 279C2H2-typeInterPro annotationAdd BLAST29
Domaini454 – 481C2H2-typeInterPro annotationAdd BLAST28
Domaini482 – 509C2H2-typeInterPro annotationAdd BLAST28
Domaini510 – 537C2H2-typeInterPro annotationAdd BLAST28
Domaini538 – 560C2H2-typeInterPro annotationAdd BLAST23
Domaini626 – 653C2H2-typeInterPro annotationAdd BLAST28
Domaini654 – 681C2H2-typeInterPro annotationAdd BLAST28
Domaini682 – 709C2H2-typeInterPro annotationAdd BLAST28
Domaini710 – 737C2H2-typeInterPro annotationAdd BLAST28
Domaini929 – 956C2H2-typeInterPro annotationAdd BLAST28
Domaini957 – 984C2H2-typeInterPro annotationAdd BLAST28
Domaini985 – 1012C2H2-typeInterPro annotationAdd BLAST28
Domaini1013 – 1037C2H2-typeInterPro annotationAdd BLAST25
Domaini1121 – 1148C2H2-typeInterPro annotationAdd BLAST28
Domaini1149 – 1176C2H2-typeInterPro annotationAdd BLAST28
Domaini1177 – 1204C2H2-typeInterPro annotationAdd BLAST28
Domaini1205 – 1232C2H2-typeInterPro annotationAdd BLAST28
Domaini1605 – 1633C2H2-typeInterPro annotationAdd BLAST29
Domaini1634 – 1661C2H2-typeInterPro annotationAdd BLAST28
Domaini1670 – 1697C2H2-typeInterPro annotationAdd BLAST28
Domaini1698 – 1725C2H2-typeInterPro annotationAdd BLAST28
Domaini1726 – 1754C2H2-typeInterPro annotationAdd BLAST29

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00096 zf-C2H2, 20 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00355 ZnF_C2H2, 30 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57667 SSF57667, 16 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 30 hits
PS50157 ZINC_FINGER_C2H2_2, 29 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A2D0TA51-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPRGRPRKPR DNTANAGDGG EEPRVESASS AEHRCSICPL TYSTENQLLK
60 70 80 90 100
HLREHEANDK PHRCDKCPQS YNVEFNLMLH KSTHSTAEPT CPVCEKKFTR
110 120 130 140 150
VASLKSHIMV HEKEENLLCS ECGDEFVLEN QLALHLEEHR RELSGTRVFT
160 170 180 190 200
CKTCSTEFPS ASQLKEHNRT HAKIRPVVSS SRNYKKNIDR SGFTNTCHHC
210 220 230 240 250
GKTFKKPSQL VRHIRIHTGE RPFKCTHCGK AFNQKVVLQT HMVRHTGEKP
260 270 280 290 300
HLCMLCPASF SQKGNLHSHV QRVHSETAGT PVYPCMDCSC VYKKLGSLNA
310 320 330 340 350
HISKMHISIM EVEESPNTQE GAEPGQTGGG TEGTEGVTDV IQQLLELSEQ
360 370 380 390 400
VTSDSAQAPP PGPNITMETA INQDILQQAL QNSGLSSIPV QSEAQGNTAV
410 420 430 440 450
PPLATEGANS HPAHIHKPTG TSAHKLLKKE KRSIFKKTVQ IPGTIREECG
460 470 480 490 500
VRWHGCPYCC KEFKKPSDLV RHIRIHTHEK PYKCAQCFRA FAVKSTLTAH
510 520 530 540 550
TKTHSGIKAF QCTHCRKSFS TSGSMKVHMR LHTGVRPFPC PHCDKIFRTS
560 570 580 590 600
GHRKTHIASH FKNLQQKKHK FPRKPNRAHV SKHNLPLPDI QLQEPILISD
610 620 630 640 650
LGLLQNQNSR AALQQYLDIV ENERPYKCTF CNKAYKKSSH LKQHVRSHTG
660 670 680 690 700
ERPYKCVQCS KGFASSGVLK AHIRTHSGLK AYKCLLCDTT FTTNGSLRRH
710 720 730 740 750
MTTHSDLRPY MCPYCQKTFK SSPNCRKHMK THRYELAQQL RQQQGSSEAP
760 770 780 790 800
PLEDPMGGAN TVEVPMGGTS ALEDPMGGAN TVTHDLQVGA TGLGTSSSIM
810 820 830 840 850
GAGPQAMLQV VSGNQTVALE APMVQDAESF VNAQHISQYG TQTLQQPSYD
860 870 880 890 900
QPALTQGFSI SEGYAQHPTL SSVQQLQDSS TLESQALNST YTQSLLNVHT
910 920 930 940 950
TETTVLLQDS NRTDYQDDED EEENSKRAYR CNVCDKGFKK SSHLKQHIRS
960 970 980 990 1000
HTGEKPYGCN LCGRNFVSTG VLKSHLNTHT GVKAFKCNVC DASFTTNGSL
1010 1020 1030 1040 1050
NRHMIIHLNT KPFRCTLCEQ SFRTHLLRRK HMKLFHAVGP RVLDGDEGIV
1060 1070 1080 1090 1100
EVDDGDPSLA KRIRSGIITF SEEQTAELAQ SDPGNDASVS EKVLIQSAAE
1110 1120 1130 1140 1150
RDRISEIKDK STLELEPKFP NCCQYCPKSF KKPSDLVRHV RIHTGEKPYK
1160 1170 1180 1190 1200
CDDCGKSFTV KSTLDCHIKT HSGQKLFTCH MCSTAFSTKG SLKVHMRLHT
1210 1220 1230 1240 1250
GSKPFKCPYC DQRFRTSGHR KTHMLCHLRH GPESRKSRHT AQGNVIAQNT
1260 1270 1280 1290 1300
PGQQAPPTAA ESLPPVGLLH STGADPNIYI HSSPVLTGQY DPNLLQQGIV
1310 1320 1330 1340 1350
GQTILPATMS ANGDLTVSLT EGLATLEGIQ LQLAPTGLLC PNVQISGIDP
1360 1370 1380 1390 1400
SNINNITLQI DPSILQQTLQ TGVLSIDSTL SSHTNAHLLA SDATGHTNVV
1410 1420 1430 1440 1450
IQNPSVAIGN LTEQEHTGSE QLAQVVGAPA LVGNGSSGAP EITLTISNSH
1460 1470 1480 1490 1500
AHTLPHTQTD THTHNANTNT LANSNQEITL TISGAGVEMG GALPLTTPPS
1510 1520 1530 1540 1550
SSSSLALSSE QLLTQSSAPS SMAVTTLAPS TSLSQNMSMS SGSVTTDSNV
1560 1570 1580 1590 1600
TLALADTQML DTVTLNLNTQ GQQFPAVVCE EGSSVQPANR IQQVTPQSEE
1610 1620 1630 1640 1650
TKVANQCFYC NMAFRSAAVL RRHWRIAHGK ERCYICSVCN KAFKRQTHLK
1660 1670 1680 1690 1700
EHEFVHTNGP SLSSQKPRVF KCFSCDKAFA KPSQLERHIR THTGERPYKC
1710 1720 1730 1740 1750
EQCDKAFNQK SALHIHTVKH TGEKPYKCEV CSISFTQKSN MKLHMKRSHG
1760 1770 1780 1790 1800
FGKHTEEGTA VDREQECVSE AAQPPPPRTE TPAGLQLHTT EPETPSDWQC

PISTVFP
Length:1,807
Mass (Da):199,127
Last modified:December 20, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0F08871004953D6B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2D0TA46A0A2D0TA46_ICTPU
zinc finger protein 236 isoform X1
znf236
1,817Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0TA53A0A2D0TA53_ICTPU
zinc finger protein 236 isoform X3
znf236
1,803Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_017351753.1, XM_017496264.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
108280829

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_017351753.1, XM_017496264.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi108280829

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7776

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00096 zf-C2H2, 20 hits
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 30 hits
SUPFAMiSSF57667 SSF57667, 16 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 30 hits
PS50157 ZINC_FINGER_C2H2_2, 29 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2D0TA51_ICTPU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2D0TA51
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 20, 2017
Last sequence update: December 20, 2017
Last modified: October 10, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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