Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

supervillin isoform X10

Gene

svil

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
supervillin isoform X10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:svilImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7998 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000221080 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1830 – 1900HPInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili470 – 494Sequence analysisAdd BLAST25

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.950.10, 1 hit
3.40.20.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR007123 Gelsolin-like_dom
IPR015628 SV/p205
IPR007122 Villin/Gelsolin
IPR003128 Villin_headpiece
IPR036886 Villin_headpiece_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11977 PTHR11977, 1 hit
PTHR11977:SF50 PTHR11977:SF50, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00626 Gelsolin, 1 hit
PF02209 VHP, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00262 GEL, 5 hits
SM00153 VHP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47050 SSF47050, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51089 HP, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

A0A2D0SA91-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MYQNAWIANY LSHVKCCQGI TGEAITKVAR PKLQQRAFSF QKQFPSEDKD
60 70 80 90 100
DVSQTTKAVD VSHIVSLPKV SELRKRFEHI SNSQSDCWDM NRKERIARRL
110 120 130 140 150
EGIDSDLQFS LPSAGLVTNR LLEEDTPRYT RATDLCDPCT VPVQHFSKDE
160 170 180 190 200
SGLSDPHSSE SVHMSRMETH TAQPEPAYNP GSVVTAEEES KAARIARYKA
210 220 230 240 250
ERRRQLCERY RILLDEEADT DHASQYSRMR RDPEGSERQY KGQVEGRYEV
260 270 280 290 300
EHNANTSNVC AGKTTAQANV EQEYSREKAE VFSEQERRMN LENQKRAHDQ
310 320 330 340 350
GRMHGEGVAP DHSAPYIDTS RETRASTEQG VTAKQVASPG DLSNEQQAHS
360 370 380 390 400
ILHKQGSCPI PEPQITEADE EKLDERAKMS VAAKRSLFRE LEKSVESAAL
410 420 430 440 450
KAQNQNAALA RRLRRGQDRY RTQPITSEEV VIAATSPGPL SQTVSVQSSV
460 470 480 490 500
TRVPSPTVVS STVTQHSSMV REQAREAQLL QETAEEEKAR HIEESQEEPD
510 520 530 540 550
LSTLSLAEKM AIFNKLTQQS SANPIRHRDT RTRRSHARYQ TQPIIPGEVA
560 570 580 590 600
QVGGGSHITP SSSAIKSTTV STVHAGDLHL AQPSVSNRYD ERDAPPWHQS
610 620 630 640 650
QPLSALQSHN GPSELPGAER EESSLGVGVR KLPSLERVKQ PKGEVATSCD
660 670 680 690 700
LQETDGNQRS RSAVAGLPKQ AVSARAAAAL TASQRVNGSA SLLQHTHAQQ
710 720 730 740 750
LLDSSREVVS EDRDRTRETE QDTEEAEEIS DIMSARQMSI KERLALLRKS
760 770 780 790 800
GEEDWRNRIN KKQDVVKVAI SEKHAQLWEV EQTFKKKDNG MIDEFAVSDQ
810 820 830 840 850
LWEPVFSSTF SSVPLSASES LDPIEPLSQT QPLLMQADER HPWRRKRIGD
860 870 880 890 900
EVVESQQLER IEMSIQERKQ LITAQEDAWK VKGRGAFNDS TQFTVAGRMV
910 920 930 940 950
KKGLAAPMVL TNPGFTPTSP KNKNAISKPL EEIEVRDDIK LESDKKLEKL
960 970 980 990 1000
ESFLGRLNSK VAGFPESTIT VTKKTVKEVM TLDDECFDKF YRHTDVLANI
1010 1020 1030 1040 1050
TSKVEIDDDF DAIFGTQMPK LTSEMVQHKR AVRPSRNVQS SRNPLKLLAA
1060 1070 1080 1090 1100
REDIRHEYTE QRLNIGVLES KRITQEKMCK NSGFSAMALA GLASKENFSS
1110 1120 1130 1140 1150
VSLRSLKVSE QSSHNSAMPY KATMLMQVKG RRHVQTRLVE PRASSLNSGD
1160 1170 1180 1190 1200
CFLLVTPQYC FIWIGEFANV IEKAKAAELA TFIQTKHDLG CRATYVHTIE
1210 1220 1230 1240 1250
EGINTHSHAS KEFWKILGGQ TSYQAAGTPE EDEFYETAIV ETNCVYRLHE
1260 1270 1280 1290 1300
DKLVPDDDFW GRVPRCTMLS PAEVLVFDFG SEVYVWHGKE VTLAQRKVAF
1310 1320 1330 1340 1350
QLAKHLWNGT FDYTTCDINP LDPGECNPLI PRKGQGRPDW AVFGRMTQHN
1360 1370 1380 1390 1400
ETTLFKEKFL DWSDSKKAST RNDNIQASEN KEVQSGECRS YDVSLMLPLS
1410 1420 1430 1440 1450
NAPIRTVLDG VDVGRGYGMV EGDDRRNFEI STLSVDVWHI LEFDYSRLPK
1460 1470 1480 1490 1500
QSIGQFHEGD TYVVKWKYMV SAAVGKRLNS ERIVGPGKER CAYFFWQGRN
1510 1520 1530 1540 1550
ATVSEKGTSA LMTVELDEER GAQIQVQQGK EPPCFLQCFN GGMMIHAGKR
1560 1570 1580 1590 1600
EEEEENTQND WRLYCVRGEK PVEGHLLEVV CHCSSLRSRS SMILLNIPKA
1610 1620 1630 1640 1650
SMYLWHGCKA QAHTQDVGRT AANKIKEQCP LEAGLHSSSK VTIHECEEGT
1660 1670 1680 1690 1700
EPVGFWEALG RRDRKAYDCM IQDLGKFNFT PRLYHLSSTS GEFVAVELIC
1710 1720 1730 1740 1750
PSREPNLVNS MPFHQEDLYS VTQPALFLVD NYHEVYLWQG WWSQDSENTG
1760 1770 1780 1790 1800
SARIRWDLDR KCAMETVLQY CREKNEKKPP KAYLIHAGLE PLTFTNMFPC
1810 1820 1830 1840 1850
WEHREDIAEI TEKEAEVCHQ IILVEDVLAR LCKTTYPLAD LMARPLPEGV
1860 1870 1880 1890 1900
DPLHLELYLS DEDFEGVGAY GKKALEMTRM EYEALPGWKQ VNLKKDKGLF
Length:1,900
Mass (Da):214,495
Last modified:December 20, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD152870740AEBCAF
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2D0S9E5A0A2D0S9E5_ICTPU
supervillin isoform X1
svil
2,278Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0S9E7A0A2D0S9E7_ICTPU
supervillin isoform X2
svil
2,277Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0SAU3A0A2D0SAU3_ICTPU
supervillin isoform X4
svil
2,253Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0S9F4A0A2D0S9F4_ICTPU
supervillin isoform X7
svil
2,220Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0S9F0A0A2D0S9F0_ICTPU
supervillin isoform X6
svil
2,234Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0SAU7A0A2D0SAU7_ICTPU
supervillin isoform X9
svil
2,219Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0S9E8A0A2D0S9E8_ICTPU
supervillin isoform X3
svil
2,271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0S9F8A0A2D0S9F8_ICTPU
supervillin isoform X11
svil
1,899Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0SA86A0A2D0SA86_ICTPU
supervillin isoform X5
svil
2,246Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2D0S9F3A0A2D0S9F3_ICTPU
supervillin isoform X8
svil
2,219Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_017339366.1, XM_017483877.1

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Ipu.6064

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
108274058

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_017339366.1, XM_017483877.1
UniGeneiIpu.6064

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi108274058

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6840

Family and domain databases

Gene3Di1.10.950.10, 1 hit
3.40.20.10, 5 hits
InterProiView protein in InterPro
IPR029006 ADF-H/Gelsolin-like_dom_sf
IPR007123 Gelsolin-like_dom
IPR015628 SV/p205
IPR007122 Villin/Gelsolin
IPR003128 Villin_headpiece
IPR036886 Villin_headpiece_dom_sf
PANTHERiPTHR11977 PTHR11977, 1 hit
PTHR11977:SF50 PTHR11977:SF50, 1 hit
PfamiView protein in Pfam
PF00626 Gelsolin, 1 hit
PF02209 VHP, 1 hit
SMARTiView protein in SMART
SM00262 GEL, 5 hits
SM00153 VHP, 1 hit
SUPFAMiSSF47050 SSF47050, 1 hit
PROSITEiView protein in PROSITE
PS51089 HP, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2D0SA91_ICTPU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2D0SA91
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 20, 2017
Last sequence update: December 20, 2017
Last modified: April 25, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again