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Protein
Submitted name:

calpain-10 isoform X2

Gene

capn10

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei68PROSITE-ProRule annotation1
Active sitei285PROSITE-ProRule annotation1
Active sitei310PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteasePROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
calpain-10 isoform X2Imported
Gene namesi
Name:capn10Imported
OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifieri7998 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus
Proteomesi
  • UP000221080 Componenti: Genome assembly

Subcellular locationi

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 364Calpain catalyticInterPro annotationAdd BLAST357

Sequence similaritiesi

Belongs to the peptidase C2 family.SAAS annotation

Family and domain databases

CDDicd00044 CysPc, 1 hit
InterProiView protein in InterPro
IPR022684 Calpain_cysteine_protease
IPR022682 Calpain_domain_III
IPR022683 Calpain_III
IPR036213 Calpain_III_sf
IPR028791 CAPN10
IPR038765 Papain_like_cys_pep_sf
IPR000169 Pept_cys_AS
IPR001300 Peptidase_C2_calpain_cat
PANTHERiPTHR10183:SF30 PTHR10183:SF30, 2 hits
PfamiView protein in Pfam
PF01067 Calpain_III, 2 hits
PF00648 Peptidase_C2, 2 hits
PRINTSiPR00704 CALPAIN
SMARTiView protein in SMART
SM00720 calpain_III, 2 hits
SM00230 CysPc, 1 hit
SUPFAMiSSF49758 SSF49758, 2 hits
SSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS50203 CALPAIN_CAT, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A2D0QFE0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTAEKDGLFE DPNFKADDSA LFSDYTTPLS RLTGKVTWLR PKEICKSPCL
60 70 80 90 100
FPDDFTEAYP KQGILGDCWL LCACNMLLKS RYLLDQRHRE SHCCVTDSGS
110 120 130 140 150
PILFRVWVTL CVKFLQLSLC PHGFLQGFLV SYDFSRFLPP RTIMPVMPPG
160 170 180 190 200
QCVWGKRGYT GQFWFQFWRN GHWTKVQIDD RLPCINNTLC FSRCHSPMAF
210 220 230 240 250
WVALLEKAYA KLHGSYERLW AGQVCEAVVD LSGGVAERWS LKKSVNTPGG
260 270 280 290 300
KSLFPELSEE MRKQSYISCC VHEAPMGASE QGQFHALNVL EWKDVKTSAG
310 320 330 340 350
AQVQLLQIRN PWGRRCWEGA WTERGYGWTL LDPSCSADLL GHTKEGEFWV
360 370 380 390 400
DEMEFRQKFD EVTVGYPISE DHCLQSIYTG SLLTHTQQIG GSWVKGHSAG
410 420 430 440 450
GCRNNSSYSS NPKFWLKVRE GGEVLMSLLQ HGPWSSLYNS QKRKSVGNTP
460 470 480 490 500
QHPYYQAIAL HVWKVDKKRF NLTRILNSTP CASSHTHTYE REVVVHAHLS
510 520 530 540 550
AGFYLLVPST FLQGAQGHFL LRVHATCPTY LSTVKVSVQQ ECVEGEWEMA
560 570 580 590 600
SVRGCWTVGS TAGGSRNFPS HGQNPHVPLI VTYDPGGTNV RITLRQHMPE
610 620 630 640 650
NSLHAIGFHI YKVPSEVDCM VISGTVCPVA SCVPHAHSQE ISVQCRLPPA
660 670 680 690 700
GYVILPSTYQ PDCSAEYTLT IAQKIPRKAI SCQEHLGQAV QEVRTSRLLM

SL
Length:702
Mass (Da):78,984
Last modified:December 20, 2017 - v1
Checksum:i93BA474056F01542
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2D0QGD8A0A2D0QGD8_ICTPU
calpain-10 isoform X1
capn10
728Annotation score:
A0A2D0QHS2A0A2D0QHS2_ICTPU
calpain-10 isoform X4
capn10
695Annotation score:
A0A2D0QGE3A0A2D0QGE3_ICTPU
calpain-10 isoform X5
capn10
669Annotation score:
A0A2D0QFE5A0A2D0QFE5_ICTPU
calpain-10 isoform X6
capn10
643Annotation score:
A0A2D0QGD1A0A2D0QGD1_ICTPU
calpain-10 isoform X3
capn10
701Annotation score:

Sequence databases

RefSeqiXP_017317388.1, XM_017461899.1

Genome annotation databases

GeneIDi108261063

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_017317388.1, XM_017461899.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi108261063

Organism-specific databases

CTDi11132

Family and domain databases

CDDicd00044 CysPc, 1 hit
InterProiView protein in InterPro
IPR022684 Calpain_cysteine_protease
IPR022682 Calpain_domain_III
IPR022683 Calpain_III
IPR036213 Calpain_III_sf
IPR028791 CAPN10
IPR038765 Papain_like_cys_pep_sf
IPR000169 Pept_cys_AS
IPR001300 Peptidase_C2_calpain_cat
PANTHERiPTHR10183:SF30 PTHR10183:SF30, 2 hits
PfamiView protein in Pfam
PF01067 Calpain_III, 2 hits
PF00648 Peptidase_C2, 2 hits
PRINTSiPR00704 CALPAIN
SMARTiView protein in SMART
SM00720 calpain_III, 2 hits
SM00230 CysPc, 1 hit
SUPFAMiSSF49758 SSF49758, 2 hits
SSF54001 SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS50203 CALPAIN_CAT, 1 hit
PS00139 THIOL_PROTEASE_CYS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2D0QFE0_ICTPU
AccessioniPrimary (citable) accession number: A0A2D0QFE0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 20, 2017
Last sequence update: December 20, 2017
Last modified: November 7, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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