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Protein
Submitted name:

G-protein coupled receptor 126 isoform X2

Gene

adgrg6

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
G-protein coupled receptor 126 isoform X2Imported
Gene namesi
Name:adgrg6Imported
OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifieri7998 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus
Proteomesi
  • UP000221080 Componenti: Genome assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei914 – 937HelicalSequence analysisAdd BLAST24
Transmembranei949 – 968HelicalSequence analysisAdd BLAST20
Transmembranei974 – 998HelicalSequence analysisAdd BLAST25
Transmembranei1018 – 1040HelicalSequence analysisAdd BLAST23
Transmembranei1066 – 1092HelicalSequence analysisAdd BLAST27
Transmembranei1113 – 1135HelicalSequence analysisAdd BLAST23
Transmembranei1141 – 1164HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501294884929 – 1300Sequence analysisAdd BLAST1272

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi92 ↔ 109PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini39 – 147CUBInterPro annotationAdd BLAST109
Domaini848 – 900GPSInterPro annotationAdd BLAST53
Domaini912 – 1165G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST254

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

CDDicd00041 CUB, 1 hit
Gene3Di2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000859 CUB_dom
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR001759 Pentraxin-related
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00431 CUB, 1 hit
PF01825 GPS, 1 hit
PF00354 Pentaxin, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00303 GPS, 1 hit
SM00159 PTX, 1 hit
SUPFAMiSSF49854 SSF49854, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51828 PTX_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 17 potential isoforms that are computationally mapped.Show allAlign All

A0A2D0Q6J2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSYISGRWW RWKFWNVLQV AVFLTCIART EVLSCQGECD EMLTASSGIF
60 70 80 90 100
TSPCYPNDYP SRQACTWTLQ APAGFVLQLT FLDFELEEAQ GCIYDSVIVN
110 120 130 140 150
TGTSSVKFCG LTANGLTLNS STNVMEVSFH SDFSVQKKGF NISYRQVAVA
160 170 180 190 200
LRNQKVTLPQ NQKDVVQVSS SVSIPALSQF TACFEIAGQS STGSGIIFSY
210 220 230 240 250
TGKDPYLTFG HNGNSVDLII GNVTCPVSDL VTLADITSIM QLFCITWSNT
260 270 280 290 300
NGVIAVYFKG NYKFKTCSNS IGMRTEIGGS FELGRGKKQG QNFNCLIYNF
310 320 330 340 350
RLWSSAMTFS ELSSLTCDAV GNVVDWNNSF WDIPASYAQT DSSLSCICYP
360 370 380 390 400
QCAHLTTTLS SIGTAVPATT SQTTSCLSSG VGCPASLTTT TSSIVNTNTI
410 420 430 440 450
PTNARTNDLP ITTSYTTTPS ISLTTTSVIT TSSATAFSPT TTSIPTAAAT
460 470 480 490 500
NPLSIHASNE FTYYRISLLV SDDLPITDDF ITQWLNQTFQ DWNHTIYVSN
510 520 530 540 550
VSILPGTDSS ITTSRRYTYK AVLVYKNTTG KLLTDADIKN RLKSVSTASF
560 570 580 590 600
TLDNIAVNAV ENCLAEETPL HYKWPESRPS VTLFIPCFPY KEQNASRTCM
610 620 630 640 650
ISPENYSSFW DQPDLMNCKD IEDIEVSQEN AAEVAVQLAD ITNNELSTVE
660 670 680 690 700
LSKVVTVVTK LVNVARINVS LASTVVTIIS NVMISSESVQ LAASEMALKT
710 720 730 740 750
MDMLVQKIEF DGPSLTITSK NLAVGISAIN SSSFSGANFS ASMAQNSSDP
760 770 780 790 800
QIDFESEVHN SLASVLLPAT LLHNLSEADV EIISRIHFMF FSKTGLFQHF
810 820 830 840 850
GSLMDQQNNG LALNSYVVAS SVGNISISNL KDPVQIEIAH LQHQWNPNRL
860 870 880 890 900
CVFWDFSIEN GSGGWNSEGC QVSPESNSNK TVCLCNHLTH FGVLMDLSGA
910 920 930 940 950
AAHIDARNTK ILTFITYIGC GISAIFSAVT ILTYVAFEKL RRDYPSKILM
960 970 980 990 1000
NLSTSLLFLN MTFLLDSWLA SYDMQGLCMA VAAFLHFFLL TSFTWMGLES
1010 1020 1030 1040 1050
IHMYIALVKV FNTYIRRYIL KFCIVGWGLP AVIVALVVAV DKNSYGKEFY
1060 1070 1080 1090 1100
GQGENGEGFC WIQSKVVFYV TCVAYFCIIF VLNVAMFIVV MMQICGRNGK
1110 1120 1130 1140 1150
RNNRTLQEEV LRNLRSVISL TFLLGMTWGF AFFAWGPVNV AFMYLFSIFN
1160 1170 1180 1190 1200
SLQGLFIFIF HCALKENVQK QWRRYLCCGK LRLADNSDWS KTATNNTKKV
1210 1220 1230 1240 1250
SSDNIGKSLS SSSFGSTTVN WTSKARVTLN PFAKRHSSSG KPYSNQANQK
1260 1270 1280 1290 1300
CSTSDSDAST SSILPVHQVL DKVKGYCSVR SDNFYKNIIL SDSFSHSTKF
Length:1,300
Mass (Da):143,197
Last modified:December 20, 2017 - v1
Checksum:iE4CEF1D88FE94141
GO

Computationally mapped potential isoform sequencesi

There are 17 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2D0Q2Q5A0A2D0Q2Q5_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,281Annotation score:
A0A2D0Q5R7A0A2D0Q5R7_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,261Annotation score:
A0A2D0Q2M0A0A2D0Q2M0_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,299Annotation score:
A0A2D0Q2W9A0A2D0Q2W9_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,238Annotation score:
A0A2D0Q6M0A0A2D0Q6M0_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,288Annotation score:
A0A2D0Q428A0A2D0Q428_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,248Annotation score:
A0A2D0Q3X9A0A2D0Q3X9_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,284Annotation score:
A0A2D0Q437A0A2D0Q437_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,245Annotation score:
A0A2D0Q3W5A0A2D0Q3W5_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,292Annotation score:
A0A2D0Q6Q5A0A2D0Q6Q5_ICTPU
G-protein coupled receptor 126 isof...
adgrg6
1,268Annotation score:
There are more potential isoformsShow all

Sequence databases

RefSeqiXP_017312970.1, XM_017457481.1

Genome annotation databases

GeneIDi108258671

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_017312970.1, XM_017457481.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi108258671

Organism-specific databases

CTDi57211

Family and domain databases

CDDicd00041 CUB, 1 hit
Gene3Di2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000859 CUB_dom
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR001759 Pentraxin-related
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00431 CUB, 1 hit
PF01825 GPS, 1 hit
PF00354 Pentaxin, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00303 GPS, 1 hit
SM00159 PTX, 1 hit
SUPFAMiSSF49854 SSF49854, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51828 PTX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2D0Q6J2_ICTPU
AccessioniPrimary (citable) accession number: A0A2D0Q6J2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 20, 2017
Last sequence update: December 20, 2017
Last modified: November 7, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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