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Protein
Submitted name:

triple functional domain protein isoform X5

Gene

trio

Organism
Ictalurus punctatus (Channel catfish) (Silurus punctatus)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseSAAS annotation, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
triple functional domain protein isoform X5Imported
Gene namesi
Name:trioImported
OrganismiIctalurus punctatus (Channel catfish) (Silurus punctatus)Imported
Taxonomic identifieri7998 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiSiluriformesIctaluridaeIctalurus
Proteomesi
  • UP000221080 Componenti: Genome assembly

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini53 – 199CRAL-TRIOInterPro annotationAdd BLAST147
Domaini1293 – 1468DHInterPro annotationAdd BLAST176
Domaini1480 – 1592PHInterPro annotationAdd BLAST113
Domaini1656 – 1721SH3InterPro annotationAdd BLAST66
Domaini1971 – 2147DHInterPro annotationAdd BLAST177
Domaini2544 – 2609SH3InterPro annotationAdd BLAST66
Domaini2678 – 2768Ig-likeInterPro annotationAdd BLAST91
Domaini2789 – 3043Protein kinaseInterPro annotationAdd BLAST255

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili755 – 785Sequence analysisAdd BLAST31
Coiled coili886 – 906Sequence analysisAdd BLAST21
Coiled coili944 – 964Sequence analysisAdd BLAST21
Coiled coili1908 – 1928Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, SH3 domainPROSITE-ProRule annotationSAAS annotation

Family and domain databases

CDDicd00160 RhoGEF, 2 hits
cd00170 SEC14, 1 hit
Gene3Di1.20.900.10, 2 hits
2.30.29.30, 2 hits
2.60.40.10, 1 hit
3.40.525.10, 1 hit
InterProiView protein in InterPro
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR011009 Kinase-like_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
IPR028570 TRIO
PANTHERiPTHR22826:SF148 PTHR22826:SF148, 5 hits
PfamiView protein in Pfam
PF00650 CRAL_TRIO, 1 hit
PF07679 I-set, 1 hit
PF00169 PH, 1 hit
PF00069 Pkinase, 1 hit
PF00621 RhoGEF, 2 hits
PF00018 SH3_1, 1 hit
PF00435 Spectrin, 4 hits
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SM00233 PH, 2 hits
SM00325 RhoGEF, 2 hits
SM00220 S_TKc, 1 hit
SM00516 SEC14, 1 hit
SM00326 SH3, 2 hits
SM00150 SPEC, 7 hits
SUPFAMiSSF48065 SSF48065, 2 hits
SSF48726 SSF48726, 1 hit
SSF50044 SSF50044, 2 hits
SSF52087 SSF52087, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
PS50010 DH_2, 2 hits
PS50835 IG_LIKE, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50002 SH3, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A2D0PUW6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSGDGAEEA AKDAADIAAF FKSDGSLPKC EPKSDVPSQI KGFRRNEEMK
60 70 80 90 100
AVEVLPILKE KVAFLSGGRD KRGGPVLTFP SRTNHDRIRQ EDLRRLIAYL
110 120 130 140 150
AGIPSEDVCK HGFTVIVDMR GSKWDSIKPL LKILQESFPC CIHIALIIKP
160 170 180 190 200
DNFWQKQRTN FGSSKFEFET TMVSLEGLSK VVDPSQLTPD FEGSLDYNHE
210 220 230 240 250
EWIEIRVAFE EFTGNARHLL ARLEEMQATV TRKDFPQELE GARRMIDEHA
260 270 280 290 300
ALKKKVMKAP VEEVDAEGQR LLQRIQSSES YATRAVPAVP GQREAQGQGQ
310 320 330 340 350
ANADTQGLVP RVTALLEQLH STRHNLHQAW HVRKLQLDQC FQLRLFEQDA
360 370 380 390 400
EKMFDWIMHN KGLFLAGYTE IGNNHSHAMD LQTQHNHFAM NCMNVYVNIN
410 420 430 440 450
RIMSVGNRLL EAGHYASQQI KQISGQLEQE WKAFAAALDE RSTLLEMSAT
460 470 480 490 500
FHQKCDQYMS NVDSWCKACG EVDLPSELQD LEDAIHHHQG LYEHITTAYS
510 520 530 540 550
EVSQDGKALL DKLQRPLTPG SADSLTASAN YSKAVHHVLD VIHEVLHHQR
560 570 580 590 600
QLENIWQHRK VRLHQRLQLC VFQQDVQQVL DWIENHGEAF LSKHTGVGKS
610 620 630 640 650
LHRARALQKR HEDFEEVAQN TYTNADKLLE AAEQLAQTGE CDPEEIYQAA
660 670 680 690 700
HQLEDRIQDF VRRVEQRKVL LDMSVAFHTH VKELWTWLEE LQKELLDDVY
710 720 730 740 750
AESVEAVQDL IKRFGQQQQT TLQVTVNVIK EGEDLIQQIR DSAISSNKAP
760 770 780 790 800
HNSSINHIES VLQQLDEAQA QMEELFQERK IKLELFLQLR IFERDAIDII
810 820 830 840 850
SDLDSWNEEL SQQMSDFDTE DLTLAEQRLQ HHADKALTMN NLTFDVIHQG
860 870 880 890 900
QELLQYVNEV QASGVELLCD RDVDMATRVQ DLLEFLHEKQ QELDVAAEQH
910 920 930 940 950
RRHLEQCVQL RHLQAEVKQV LGWIRNGESM LNAGLITASS LQEAEQLQRE
960 970 980 990 1000
HEQFQHAIEK THQSALQVQQ KAEAMLQANH YDMDMIRDCA ENVASHWQQL
1010 1020 1030 1040 1050
MLKMEDRLKL VNASVAFYKT SEQVCSVLES LEQEYKREED WCGGADKLGP
1060 1070 1080 1090 1100
NCETDHVTPM ISKHLEQKEA FLKACTLARR NADVFLKYMH RNSVNMPGML
1110 1120 1130 1140 1150
SHVKAPEQQV KNILNELLQR ENRVLHFWTM RKRRLDQCQQ YVVFERSAKQ
1160 1170 1180 1190 1200
ALEWIHDTGE FYLSTHTSTG SSIHHTQELL KEHEDFHITA KQTKERVKLL
1210 1220 1230 1240 1250
IQLADGFCDK GHAHAAEIKK WVTAVDKRYR DFSLRMDKYR SSLEKALGIS
1260 1270 1280 1290 1300
SDSNKASKDL QLDIIPASAP GSEVKLRDAA HELNEEKRKS ARRKDFIMAE
1310 1320 1330 1340 1350
LIQTEKAYVR DLRECMDTYL WEMTSGVEEI PPGIVNKEHI IFGNMQDLYE
1360 1370 1380 1390 1400
FHHNIFLKEL EKYEQLPEDV GHCFVTWADK FQMYVNYCKN KPDSTQLILE
1410 1420 1430 1440 1450
HAGSYFDEIQ QRHRLANSIS SYLIKPVQRI TKYQLLLKEL LTCCEEGKGE
1460 1470 1480 1490 1500
IKDGLEVMLS VPKRANDAMH LSMLEGFDEN IESQGELILQ ESFQVWDPKT
1510 1520 1530 1540 1550
LIRKGRERHL FLFEMSLVFS KEVKDSNGRS KYIYKSKLFT SELGVTEHVE
1560 1570 1580 1590 1600
GDPCKFALWV GRTPTSDNKI VLKASSIENK QDWIKHIREV IQERTVHLKG
1610 1620 1630 1640 1650
ALKEPIHIPK PSTTKHKARR DGEDLDSQGE GSSQPDTISL ASRTSQNTLD
1660 1670 1680 1690 1700
SDKLSGGCEL TVVIHDFMAG NNNELSVRRG QTVEVLERLH DKPDWCLVRT
1710 1720 1730 1740 1750
TDRSPALEGI VPCAMLCIAH SRSSMEMEGL FNHKDTLSVC SNDAILPGSS
1760 1770 1780 1790 1800
ATLQPGHMMG SQSSPGPKRP GNTLRKWLTS PVRRLSSGKA DGHVKKLAHK
1810 1820 1830 1840 1850
HKKNRADVRK SAEVGSQKDS DDSAATPQDE TVEERVRNEG LSSGTLSKSS
1860 1870 1880 1890 1900
SSGMQSCGEE EGEEGADSVP LPPPMAIQQH SLLQPDPQDD KTSSRLSVRP
1910 1920 1930 1940 1950
SSSETPSAAE LVSAIEELVK SKMALEDRPS SLSVEQGDSS SPSFNPSDNS
1960 1970 1980 1990 2000
LLSSSSPIDE MEERKTGFLK RRHYVLLELV ETERDYVRDL GLVVEGYMAR
2010 2020 2030 2040 2050
MKEEGVPDDM KGKDKIVFGN IHQIYDWHRD FFLGELERCI DDPDHLGTLF
2060 2070 2080 2090 2100
VKHERRLHMY IVYCQNKPKS EHIVSEYIDT YFEDLKQRLG QRLQITDLLI
2110 2120 2130 2140 2150
KPVQRIMKYQ LLLKDFLKFS KKAGLDSLDL ERAVEVMCIV PKRCNDMMNV
2160 2170 2180 2190 2200
GRLQGFDGKI VAQGRLLLQD TFMVSDSDGG LLGRMKERRV FLFEQIVIFS
2210 2220 2230 2240 2250
EPLDKKRGFS MPGFLYKNGI KVSCLGLEDS ADGDPCKFTM TSRMPNGSIE
2260 2270 2280 2290 2300
AFLLHSSHPG VRQVWTLQIN QILEAQRNFL TALTSPVDYQ RNHVGGSIST
2310 2320 2330 2340 2350
PIGSSVSSGG QGVARGGGMA VPVASGCRSR PSRIPQPSRL PQPLRHHSPA
2360 2370 2380 2390 2400
LGPGASEPDG PNKISGMPPR PLPSCTTDPD TSRDSAKLKL SDSPQSKRSE
2410 2420 2430 2440 2450
PVEDVSKENQ EISVPAQIPR ATVPPLALVK PRPGTISPVG TPLATSGFKD
2460 2470 2480 2490 2500
FLAPCSPGPK NGGCSTPSSS TSFWSSIPGS PAGRPGSFTF PGEACETPSR
2510 2520 2530 2540 2550
PNQNQSHRHS SHSKDADRMS TCSSASEQSV QSTQSNGSES SSSSNISTML
2560 2570 2580 2590 2600
VTQDYVALKE DEINVCQGEV VQILASNQQN MFLVFRAATD QRPAAEGWIP
2610 2620 2630 2640 2650
GYVLGHTSAS TPDAPEGTIK KSSSWHTSLR IRKKSERREK EGKKEAKLEN
2660 2670 2680 2690 2700
GYRKSREGLP NKVSVKLLNP NYIYDVPPEI LVPLSDVTCD KGECVTLRCK
2710 2720 2730 2740 2750
VCGRPKAAVT WKGPDQSTLS NNGHFSIAYS ETGEATLRIV GVVSEDDGIY
2760 2770 2780 2790 2800
TCIATNDVGS VITTASLRVL GTSSDGIRVM WKDNFESFYT EVAELGRGRF
2810 2820 2830 2840 2850
AVVKRCDQKG TKRTVAVKLV NKKLMKRDQV TQELSILKRL QHPHIISLQD
2860 2870 2880 2890 2900
IFETPSSYAL VLEMADQGRL LDFIVSWGNL TEEKVAFYLR DILEALHYLH
2910 2920 2930 2940 2950
NCRIAHLDVK PENLVVDQSS SQLTVKLTDF GDAVQLNSAH YIHPLLGSPE
2960 2970 2980 2990 3000
FAAPEVVLGE PVSLTSDLWS LGVVTYVILS GASPFLDESV EETCLNICRL
3010 3020 3030 3040 3050
DFSFPDDYFQ GVSQEARDFV CLLLRTEPNR RPAPSLCLQE PWLRPGTGQG
3060 3070 3080 3090
STEGIDTSRL ISFIERRKHH NDLRPLGGIR PFLHSRLQPR I
Length:3,091
Mass (Da):348,445
Last modified:December 20, 2017 - v1
Checksum:i572DD8662E372E43
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2D0PXI4A0A2D0PXI4_ICTPU
triple functional domain protein is...
trio
3,105Annotation score:
A0A2D0PUZ4A0A2D0PUZ4_ICTPU
triple functional domain protein is...
trio
3,101Annotation score:
A0A2D0PWN1A0A2D0PWN1_ICTPU
triple functional domain protein is...
trio
3,101Annotation score:
A0A2D0PTE6A0A2D0PTE6_ICTPU
triple functional domain protein is...
trio
3,095Annotation score:
A0A2D0PV01A0A2D0PV01_ICTPU
triple functional domain protein is...
trio
3,057Annotation score:

Sequence databases

RefSeqiXP_017309829.1, XM_017454340.1

Genome annotation databases

GeneIDi108256988

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_017309829.1, XM_017454340.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi108256988

Organism-specific databases

CTDi7204

Family and domain databases

CDDicd00160 RhoGEF, 2 hits
cd00170 SEC14, 1 hit
Gene3Di1.20.900.10, 2 hits
2.30.29.30, 2 hits
2.60.40.10, 1 hit
3.40.525.10, 1 hit
InterProiView protein in InterPro
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR011009 Kinase-like_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
IPR028570 TRIO
PANTHERiPTHR22826:SF148 PTHR22826:SF148, 5 hits
PfamiView protein in Pfam
PF00650 CRAL_TRIO, 1 hit
PF07679 I-set, 1 hit
PF00169 PH, 1 hit
PF00069 Pkinase, 1 hit
PF00621 RhoGEF, 2 hits
PF00018 SH3_1, 1 hit
PF00435 Spectrin, 4 hits
SMARTiView protein in SMART
SM00409 IG, 1 hit
SM00408 IGc2, 1 hit
SM00233 PH, 2 hits
SM00325 RhoGEF, 2 hits
SM00220 S_TKc, 1 hit
SM00516 SEC14, 1 hit
SM00326 SH3, 2 hits
SM00150 SPEC, 7 hits
SUPFAMiSSF48065 SSF48065, 2 hits
SSF48726 SSF48726, 1 hit
SSF50044 SSF50044, 2 hits
SSF52087 SSF52087, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50191 CRAL_TRIO, 1 hit
PS50010 DH_2, 2 hits
PS50835 IG_LIKE, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS50002 SH3, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2D0PUW6_ICTPU
AccessioniPrimary (citable) accession number: A0A2D0PUW6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 20, 2017
Last sequence update: December 20, 2017
Last modified: July 18, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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