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Protein

Olfactory receptor

Gene

OR4C15

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionG-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer
Biological processOlfactionUniRule annotationSAAS annotation, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptorUniRule annotation
Gene namesi
Name:OR4C15Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:15171 OR4C15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei41 – 58HelicalUniRule annotationAdd BLAST18
Transmembranei78 – 102HelicalUniRule annotationAdd BLAST25
Transmembranei114 – 135HelicalUniRule annotationAdd BLAST22
Transmembranei155 – 173HelicalUniRule annotationAdd BLAST19
Transmembranei193 – 215HelicalUniRule annotationAdd BLAST23
Transmembranei247 – 278HelicalUniRule annotationAdd BLAST32
Transmembranei290 – 311HelicalUniRule annotationAdd BLAST22
Transmembranei323 – 342HelicalUniRule annotationAdd BLAST20

Keywords - Cellular componenti

Cell membraneUniRule annotationSAAS annotation, Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000181939

Expressioni

Gene expression databases

ExpressionAtlasiA0A2C9F2M4 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 340G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST248

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00900000141017
KOiK04257
OMAiCFSTVIA

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2C9F2M4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFSMTTEALN NFALGCTNLL MTMIPQIDLK QIFLCPNCRL YMIPVGAFIF
60 70 80 90 100
SLGNMQNQSF VTEFVLLGLS QNPNVQEIVF VVFLFVYIAT VGGNMLIVVT
110 120 130 140 150
ILSSPALLVS PMYFFLGFLS FLDACFSSVI TPKMIVDSLY VTKTISFEGC
160 170 180 190 200
MMQLFAEHFF AGVEVIVLTA MAYDRYVAIC KPLHYSSIMN RRLCGILMGV
210 220 230 240 250
AWTGGLLHSM IQILFTFQLP FCGPNVINHF MCDLYPLLEL ACTDTHIFGL
260 270 280 290 300
MVVINSGFIC IINFSLLLVS YAVILLSLRT HSSEGRWKAL STCGSHIAVV
310 320 330 340 350
ILFFVPCIFV YTRPPSAFSL DKMAAIFYII LNPLLNPLIY TFRNKEVKQA
360 370
MRRIWNRLMV VSDEKENIKL
Length:370
Mass (Da):41,711
Last modified:December 20, 2017 - v1
Checksum:iA61CE186CB44C982
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q8NGM1OR4CF_HUMAN
Olfactory receptor 4C15
OR4C15
316Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001998 Genomic DNA No translation available.
RefSeqiNP_001001920.1, NM_001001920.1
UniGeneiHs.589003

Genome annotation databases

EnsembliENST00000314644; ENSP00000324958; ENSG00000181939
GeneIDi81309
KEGGihsa:81309

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP001998 Genomic DNA No translation available.
RefSeqiNP_001001920.1, NM_001001920.1
UniGeneiHs.589003

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000314644; ENSP00000324958; ENSG00000181939
GeneIDi81309
KEGGihsa:81309

Organism-specific databases

CTDi81309
HGNCiHGNC:15171 OR4C15
OpenTargetsiENSG00000181939
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00900000141017
KOiK04257
OMAiCFSTVIA

Gene expression databases

ExpressionAtlasiA0A2C9F2M4 baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR000276 GPCR_Rhodpsn
IPR017452 GPCR_Rhodpsn_7TM
IPR000725 Olfact_rcpt
PfamiView protein in Pfam
PF13853 7tm_4, 1 hit
PRINTSiPR00237 GPCRRHODOPSN
PR00245 OLFACTORYR
PROSITEiView protein in PROSITE
PS00237 G_PROTEIN_RECEP_F1_1, 1 hit
PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2C9F2M4_HUMAN
AccessioniPrimary (citable) accession number: A0A2C9F2M4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 20, 2017
Last sequence update: December 20, 2017
Last modified: November 7, 2018
This is version 10 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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