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Entry version 9 (02 Jun 2021)
Sequence version 1 (11 Dec 2019)
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Protein
Submitted name:

AT-hook containing transcription factor 1

Gene

AHCTF1

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AT-hook containing transcription factor 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AHCTF1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008227 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:96050, AHCTF1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000011581

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A287A0A3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 490ELYS-bbInterPro annotationAdd BLAST490
Domaini723 – 945ELYSInterPro annotationAdd BLAST223

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1271 – 1306DisorderedSequence analysisAdd BLAST36
Regioni1738 – 1763DisorderedSequence analysisAdd BLAST26
Regioni1785 – 1841DisorderedSequence analysisAdd BLAST57
Regioni1900 – 2078DisorderedSequence analysisAdd BLAST179
Regioni2092 – 2130DisorderedSequence analysisAdd BLAST39
Regioni2179 – 2214DisorderedSequence analysisAdd BLAST36
Regioni2226 – 2247DisorderedSequence analysisAdd BLAST22

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1276 – 1290Polar residuesSequence analysisAdd BLAST15
Compositional biasi1738 – 1756Basic and acidic residuesSequence analysisAdd BLAST19
Compositional biasi1785 – 1809Polar residuesSequence analysisAdd BLAST25
Compositional biasi1900 – 1930Polar residuesSequence analysisAdd BLAST31
Compositional biasi1931 – 2003Basic and acidic residuesSequence analysisAdd BLAST73
Compositional biasi2041 – 2055Basic and acidic residuesSequence analysisAdd BLAST15
Compositional biasi2061 – 2078Basic and acidic residuesSequence analysisAdd BLAST18
Compositional biasi2179 – 2204Basic and acidic residuesSequence analysisAdd BLAST26
Compositional biasi2232 – 2246Basic and acidic residuesSequence analysisAdd BLAST15

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000018900

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032040, ELYS-bb
IPR025151, ELYS_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13934, ELYS, 1 hit
PF16687, ELYS-bb, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A287A0A3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRDLTAQVTS DLLQFPEVTI QALGEDEITL ESVLRGKFAA GRNGLACLAC
60 70 80 90 100
GPQLEVVNSL TGERLSAYRF SGVNEQPPIV LAVKEFSWQK RTGLLIGLEE
110 120 130 140 150
FEGSVLCLYD LGLSRVVKAV VLPGRVTAIE PIINHGGASA STQHLHPSLR
160 170 180 190 200
WLFGVAAVVT DVGQILLIDL CLDDLSGSQN EVEASDLEVI TGIPAEVPHI
210 220 230 240 250
RENVMREGRH LCFQLVSPSG IAVSTLSYIN RTNQLAVGFS DGYLALWNMK
260 270 280 290 300
SMKREYYTQL EGGRVPVYAV TFQEPENDPR NCCYLWAVQS TQDSEGDVLS
310 320 330 340 350
LHLLQLAFGD RKCLASGQIL YEGLEYCEER YTLDLTGGGM FPVRGQTGNT
360 370 380 390 400
KLLGCQSIEK FRSHGDREEG MNEALSPDTS VSVFTWQVNI YGQGKPSIYL
410 420 430 440 450
GLFDINRWYH AQMPDSLRSG EYLHNCSYFA LWSLDSVVSK TSPHYVLDVL
460 470 480 490 500
VHERSLSRGV PPSYPPPEQF FNPSTYNFDA TCLLNSGVVH ITCTGFQKET
510 520 530 540 550
LTFLKKSGPS LNEVIPDGYN RCLVAGLLSP RLIDIQPSSL SQEEQLEAIL
560 570 580 590 600
SAAIQTSSLG LLTGCIRRWI TEEQPNSAAN LRFVLEWTWN KVVFTKGEFD
610 620 630 640 650
RLCAPLFDGS CRFIDPQTIQ SIQQCSLLLS NLNTVLSCFA TEAQEITERG
660 670 680 690 700
VMDLSNKYTV SQLICQYAQV VLWFSHSGLL PEGLDDAVQL SRLCYNYPVI
710 720 730 740 750
QNYYTSRRQK CERLSRGKWN PDCLMIDGMV SQLGDRVEKL WKRDEGGTGK
760 770 780 790 800
YPPTSLHALL DIYLLEDVTE ASKHSITIYL LLDIMYSFPN KTDTSIESFP
810 820 830 840 850
TAFAISWGQV KLIQGFWLID HNDYESGLDL LFHPATAKPV SWQHSKIIQA
860 870 880 890 900
FMSQGEPRQA LRYIQTMRPT VSTDSDVTLH LTVLLFNRCM VEAWDLVRQH
910 920 930 940 950
SSRLNIEELL KHTYEVCQEM GLMEDLLKLP FTDTEQECLV KFLQSSASIQ
960 970 980 990 1000
NHEFLLVHHL QRANYIPALK LNQTLKINLM NDRDPRLRER SVARNSILDQ
1010 1020 1030 1040 1050
YGKILPRVQR KLAIERAKPY RLSASSVLRE VSRPKPLSAV PKQAVTGTVF
1060 1070 1080 1090 1100
TRSTFINNVL SKIGEVWASS EPKNSLSVYN SPKIEAPSPV VYSLPDLELP
1110 1120 1130 1140 1150
EAFVGTPISK ASQKISRLLD LVVQPVPQPS QCLGFIQHIP PRSPLYLVSS
1160 1170 1180 1190 1200
SLSLSSQLKE SRQNASRASE LHLLETPLVV KKAKTLAMSV TSSGFAEFTP
1210 1220 1230 1240 1250
QSILRSGLRT TPLASPSLSP GRSLTPPLRL KETRISFMEE GLTTEWAAGA
1260 1270 1280 1290 1300
ADDSKTKVFI TEPFHKCGVP AETGWQKNKD KTTSFSMSSP EKDHQEVDVQ
1310 1320 1330 1340 1350
SQDTTSQGLE KLDISVEHSN ASTRSDQTTL EYQDAPLPED LEDIFMASMP
1360 1370 1380 1390 1400
PSSSTELITN LTGQSEKDSD KDVFESEVTP PDLEKQMEDA ETRDLLVAEG
1410 1420 1430 1440 1450
ALSELNHLSP SQGVEASCVS SIHEGSILTP ESMVPVLDKG LVSIETCTST
1460 1470 1480 1490 1500
IRTAVADVLG DNGSSGLLIS ESPAISEHRL DQEVALNVKE DHEIEVDVLK
1510 1520 1530 1540 1550
ARVDLPEEKP PISDDPPDTQ EIHVVEHEKV EVQDSGQEAR NLSFNELYPS
1560 1570 1580 1590 1600
GTLKLQYNFD TIEKQFCDLP DSKDSAECDI AEVDRELFVA QSNFTLILEG
1610 1620 1630 1640 1650
EEGEIETGDS AASNVLAKAA NAATEEKHTC SRENDSHRHV ANLPSVLTSD
1660 1670 1680 1690 1700
QESQKVETLP YVPEPIKVAI AENLLDVIKD TRSKEITSDT MEQSIHDNIP
1710 1720 1730 1740 1750
LISQKVMCST KLAKTPFKTV QETSAVTINV SQINDMISSR TRKKRRVQDM
1760 1770 1780 1790 1800
SVKSAHQEES ADVATPEMLG LSIMKKTRKT KEISGAFESA SSDDKGISQN
1810 1820 1830 1840 1850
QQTPQNSVTP RRGRRKKEIN QDTSEDINSV EQELEATPGR ELRRVKSSQL
1860 1870 1880 1890 1900
LESVTEESSF RKDVKLSSVT KRTPKRIKKS VENQESVEVI NDLKVSKIAS
1910 1920 1930 1940 1950
PSRSTRKLRS ACLETSESTA GESTEQQLPL QRNRRVRKRE GSASDVVEDS
1960 1970 1980 1990 2000
KFDSSQRKPP AEFDTPATPR KRGRPRKTNP SEDVESKAVK GARSPETREG
2010 2020 2030 2040 2050
LNIQRRSTRN TPAKSGNTEV GKLALETSVF VPSEELATPV SSKKKPTKRT
2060 2070 2080 2090 2100
ENQSQKRPLR SISEKCIDEE MTHKEVDDQE EKLLATVALT KSSRGTRTRS
2110 2120 2130 2140 2150
SKAVLLPDLS EPKNESLFSP PVSKIPRKEK AKKIEAPAQL KELVSDLSSQ
2160 2170 2180 2190 2200
FVFSPPALRT RQKNLTNTSK LIDKLEDDAP SVETVEKQQV KRARTTKTRQ
2210 2220 2230 2240 2250
ASKNTEKESW SPPPVEVKLI SPLASPVDGV KSRPRRAAEV TGKTLGRSRK
2260 2270 2280 2290 2300
KVSSFPKQVL RRKMLTTTII QDPKNPEHTK TFIFDLAYWS HNGFQKDKDG
2310 2320 2330
VFISVDPSSK FAGQVSCFKT TLMDVGFCCC FFK
Length:2,333
Mass (Da):259,695
Last modified:December 11, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4D777FB414D36C8E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F1S8P4F1S8P4_PIG
AT-hook containing transcription fa...
AHCTF1
2,281Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A287A3H9A0A287A3H9_PIG
AT-hook containing transcription fa...
AHCTF1
2,199Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5G2R3A1A0A5G2R3A1_PIG
AT-hook containing transcription fa...
AHCTF1
2,307Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AEMK02000071 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSSCT00000047033; ENSSSCP00000037183; ENSSSCG00000010863

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000071 Genomic DNA No translation available.

3D structure databases

SMRiA0A287A0A3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000011581

Genome annotation databases

EnsembliENSSSCT00000047033; ENSSSCP00000037183; ENSSSCG00000010863

Organism-specific databases

VGNCiVGNC:96050, AHCTF1

Phylogenomic databases

GeneTreeiENSGT00390000018900

Family and domain databases

InterProiView protein in InterPro
IPR032040, ELYS-bb
IPR025151, ELYS_dom
PfamiView protein in Pfam
PF13934, ELYS, 1 hit
PF16687, ELYS-bb, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A287A0A3_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A287A0A3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 11, 2019
Last sequence update: December 11, 2019
Last modified: June 2, 2021
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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