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Protein
Submitted name:

Uncharacterized protein

Gene

ERBIN

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-SSC-1227986 Signaling by ERBB2
R-SSC-8863795 Downregulation of ERBB2 signaling

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:ERBINImported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 16

Expressioni

Gene expression databases

ExpressionAtlasiA0A286ZYU9 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1212 – 1301PDZInterPro annotationAdd BLAST90

Phylogenomic databases

GeneTreeiENSGT00840000129686

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR032927 Erbin
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR001478 PDZ
IPR036034 PDZ_sf
PANTHERiPTHR44896 PTHR44896, 2 hits
PfamiView protein in Pfam
PF13855 LRR_8, 4 hits
PF00595 PDZ, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 11 hits
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 13 hits
PS50106 PDZ, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

A0A286ZYU9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTTKRSLFVR LVPCRCLRGE EETVTTLDYS HCSLEQVPKE IFTFEKTLEE
60 70 80 90 100
LYLDANQIEE LPKQLFNCQS LHKLSLPDND LTTLPASIAN LINLRELDVS
110 120 130 140 150
KNGIQEFPEN IKNCKVLTVV EASVNPISKL PDGFSQLLNL TQLYLNDAFL
160 170 180 190 200
EFLPANFGRL TKLQILELRE NQLKMLPKTM NRLTQLERLD LGSNEFTEVP
210 220 230 240 250
EVLEQLSGLK EFWMDGNRLT FIPGFIGSLK QLTYLDVSKN NIEVVEEGIS
260 270 280 290 300
ACENLQDLLL SSNSLQQLPE TIGSLKNVTT LKIDENQLIY LPDSIGGLIS
310 320 330 340 350
IEELDCSFNE LEALPSSVGQ LTNIRTFAAD HNYLQQLPPE IGSWKNITVL
360 370 380 390 400
FLHSNKLETL PEEMGDMQKL KVINLSDNRL KNLPFSFTKL QQLTAMWLSD
410 420 430 440 450
NQSKPLIPLQ KETDSETQKM VLTNYMFPQQ PRTEDVMFIS DNESFNPSLW
460 470 480 490 500
EEQRKQRAQV AFECDEDKDE REAPPREGNL KRYPTPYPDE LKNMVKTVQT
510 520 530 540 550
IVHRLKDEET NEDSGKDLKP HEDQQVVNNE VGVKTSESAT PVKSKADERE
560 570 580 590 600
KYMIGNSIQK TSEPEAEVSP GSLPVTANMK ASENLKHIVN HDDVFEESEE
610 620 630 640 650
LSSDEEMKMA EMRPPLIETS INQPKVVALS NNKKDDTKDT DSLSDEVTHN
660 670 680 690 700
SNQNNSNCSS PSRMSDSVSL NTDSSQDTSL CSPVKQTHIG INSKIRQEDE
710 720 730 740 750
NFNSLLQNGD ILNHSTEEKF KVPDKKDFNL PEYDLNIEER LVLIEKGIDS
760 770 780 790 800
TATCDESHKL DHINMNLNKL VTNDTFQPEI VERSKTQDIV LGAGFLSRNA
810 820 830 840 850
EGEAEHLENG NEYPNLECIN KVNGHSEETP QSPRRTESHD TDSSIDVGLS
860 870 880 890 900
KSTEDLSPQR SGPVGPVVKS HSITNMETGG LKIYDIHSDN GPQQPSATVK
910 920 930 940 950
VTSTIDGKNI VRSKSATLLY DQPLQVFTGS SSSSDLISGT KAIFKFDSNH
960 970 980 990 1000
NPEELNIIRG PTTSGPQSTP QIYGPPQYNI QYSSGTAVKD TLWHSKQNPQ
1010 1020 1030 1040 1050
IDHVSFPPQR LPRSESTENH SHAKHSANMN FSNHNNVRAS TGYHLHQRLG
1060 1070 1080 1090 1100
PGRHGEMWAV SPNDRLIPGA TRTTIQRQSS VSSAASVNLG EPGPMRRAQV
1110 1120 1130 1140 1150
PEGDYLSYRE LHSVGRTPPM MSGSQRPLSA RTYSIDGQNA SRPQSARPSV
1160 1170 1180 1190 1200
SEIPERTMSV SDFNYSRTSP SKRPNARVGS EHSLLDPPGK SKVPHDWREQ
1210 1220 1230 1240 1250
VLRHIEAKKL EKIRVRVEKD PELGFSISGG VGGRGNPFRP DDDGIFVTRV
1260 1270 1280 1290 1300
QPEGPASKLL QPGDKIIQAN GYSFINIEHG QAVSLLKTFQ NTVELIVLRE

VSS
Length:1,303
Mass (Da):145,852
Last modified:November 22, 2017 - v1
Checksum:i88423E101B770FCB
GO

Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A287AVI3A0A287AVI3_PIG
Uncharacterized protein
ERBIN
1,496Annotation score:
K7GKZ4K7GKZ4_PIG
Uncharacterized protein
ERBIN
1,448Annotation score:
F1SKS4F1SKS4_PIG
Uncharacterized protein
ERBIN
1,386Annotation score:
F1SKS3F1SKS3_PIG
Uncharacterized protein
ERBIN
1,461Annotation score:
A0A287A2J8A0A287A2J8_PIG
Uncharacterized protein
ERBIN
1,408Annotation score:
A0A287B119A0A287B119_PIG
Uncharacterized protein
ERBIN
1,378Annotation score:
A0A287BME0A0A287BME0_PIG
Uncharacterized protein
ERBIN
1,456Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000102 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSSSCT00000057010; ENSSSCP00000036646; ENSSSCG00000016954

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000102 Genomic DNA No translation available.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000057010; ENSSSCP00000036646; ENSSSCG00000016954

Phylogenomic databases

GeneTreeiENSGT00840000129686

Enzyme and pathway databases

ReactomeiR-SSC-1227986 Signaling by ERBB2
R-SSC-8863795 Downregulation of ERBB2 signaling

Gene expression databases

ExpressionAtlasiA0A286ZYU9 baseline and differential

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR032927 Erbin
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR001478 PDZ
IPR036034 PDZ_sf
PANTHERiPTHR44896 PTHR44896, 2 hits
PfamiView protein in Pfam
PF13855 LRR_8, 4 hits
PF00595 PDZ, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 11 hits
SM00228 PDZ, 1 hit
SUPFAMiSSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 13 hits
PS50106 PDZ, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A286ZYU9_PIG
AccessioniPrimary (citable) accession number: A0A286ZYU9
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: October 10, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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