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Protein
Submitted name:

Vacuolating cytotoxin A

Gene

vacA

Organism
Helicobacter pylori (Campylobacter pylori)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Vacuolating cytotoxin AImported
Gene namesi
Name:vacAImported
OrganismiHelicobacter pylori (Campylobacter pylori)Imported
Taxonomic identifieri210 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Subcellular locationi

GO - Cellular componenti

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1031 – 1304AutotransporterInterPro annotationAdd BLAST274

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili993 – 1013Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3Di2.40.128.130, 1 hit
InterProiView protein in InterPro
IPR005546 Autotransporte_beta
IPR036709 Autotransporte_beta_dom_sf
IPR006315 OM_autotransptr_brl
IPR003842 Vacuolating_cytotoxin
PfamiView protein in Pfam
PF02691 VacA, 1 hit
PRINTSiPR01656 VACCYTOTOXIN
SMARTiView protein in SMART
SM00869 Autotransporter, 1 hit
SUPFAMiSSF103515 SSF103515, 1 hit
TIGRFAMsiTIGR01414 autotrans_barl, 1 hit
PROSITEiView protein in PROSITE
PS51208 AUTOTRANSPORTER, 1 hit

Sequencei

Sequence statusi: Complete.

A0A286P1E1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MELQQTHRKI NRPLVSLALV GLLVSITPQK SHAAFFTTVI IPAIVGGIAT
60 70 80 90 100
GAAVGTVSGL LGWGLKQAEE ANKTPDKPDK VWRIQAGRGF NEFPNKEYDL
110 120 130 140 150
YKSLLSSKID GGWDWGNAAR HYWIKGGQWN KLEVDMKDAV GTYKLSGLRN
160 170 180 190 200
FTGGDLDVNM QKATLRLGQF NGNSFTSFKD GADRTTRVDF NAKNILIDNF
210 220 230 240 250
LEINNRVGSG AGRKASSTVL TLQASEGITS GKNAEISLYD GATLNLASNS
260 270 280 290 300
VKLMGNVWMG RLQYVGAYLA PSYSTINTSK VTGEVNFNHL TVGDHNAAQA
310 320 330 340 350
GIIASKKTYI GTLDLWQSAG LNIIAPPEGG YKDKSNNTNS QSGAKNDKNE
360 370 380 390 400
SAKNDKNESA KNDKQESSQN NSNTQVINPP NSGQKTEIQP TQVIDGPFAG
410 420 430 440 450
AKDTVVNINR INTNADGTIK VGGYTASLTT NAAHLNIGKG GVNLSNQASG
460 470 480 490 500
RSLLVENLTG NITVDGALMV NNQVGGYALA GSSANFEFKA GTDTKNGTIA
510 520 530 540 550
FNNNISLGRF VNLKASAHTV NFKELNTGNG GFNTLDFSGV TNKVNINKLI
560 570 580 590 600
TASTNVAIKN FNINELLVKT NGISVGEYTN FSEDIGNQSR INTVRLETGT
610 620 630 640 650
RSIYSGGVKF KGGEKLVIND FYYAPWNYFD ARNIKNVEIT NKLAFGPQGS
660 670 680 690 700
PWGTAKLMFN NLTLGPNAVM DYSQFSNVTI QGNFVNNQGT INYLVRGGNI
710 720 730 740 750
ETLSVGNAAV MSFNNDIDSA TGFYKPLIKI NSAQDLIKNK EHVLLKAKII
760 770 780 790 800
GYENASLGTN SISNANLIEQ FNERLALYNN NNRMDTCVVR NTDDIKACGM
810 820 830 840 850
AIGDQAMVNN PDNYKYLIGK AWKNIGISKT ANGSKISVRY LGNATPAENG
860 870 880 890 900
GNTTNLPTNA TNNARFARYA LIKNAPFAQT SATPNLVAIN KHDFGTIESV
910 920 930 940 950
FELANRSEDI DTLYAHSGTQ GRDLLQTLLI DSHDAGYART MIDATSANEI
960 970 980 990 1000
TKQLNTATDA LNNIASLEHK TSGLQTLSLS NAMILNSRLV NLSRRHTNNI
1010 1020 1030 1040 1050
DSFAQRLQAL KDQRFASLES AAEVLYQFAP KYEKPTNVWA NAIGGASLNS
1060 1070 1080 1090 1100
GGNTSLYGTS AGVDAYLNEK VEAIVGGFGS YGYSSFNNQA NSLNSGANNA
1110 1120 1130 1140 1150
NFGVYSRIFA NRHEFDFEAQ GAVGSDQSSL NFKSALLRDL NQSYNYLAYG
1160 1170 1180 1190 1200
AATRASYGYD FAFLRNALVL KPSVGVSYNH LGSTNFESNS TNKTALKNGT
1210 1220 1230 1240 1250
SSQHLFNASA NVEARYYYGD TSYFYMNAGV LQEFANFGSS NAVSLNTFKV
1260 1270 1280 1290 1300
NAARNPLNTH ARVMMGGELK LAKEVFLNLG FIYLHNLISN AGYFASNLGM

RYSF
Length:1,304
Mass (Da):140,850
Last modified:November 22, 2017 - v1
Checksum:i2CAC33FA0075FF3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LC185415 Genomic DNA Translation: BBA30834.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
LC185415 Genomic DNA Translation: BBA30834.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.40.128.130, 1 hit
InterProiView protein in InterPro
IPR005546 Autotransporte_beta
IPR036709 Autotransporte_beta_dom_sf
IPR006315 OM_autotransptr_brl
IPR003842 Vacuolating_cytotoxin
PfamiView protein in Pfam
PF02691 VacA, 1 hit
PRINTSiPR01656 VACCYTOTOXIN
SMARTiView protein in SMART
SM00869 Autotransporter, 1 hit
SUPFAMiSSF103515 SSF103515, 1 hit
TIGRFAMsiTIGR01414 autotrans_barl, 1 hit
PROSITEiView protein in PROSITE
PS51208 AUTOTRANSPORTER, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A286P1E1_HELPX
AccessioniPrimary (citable) accession number: A0A286P1E1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: October 10, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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