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Entry version 7 (05 Jun 2019)
Sequence version 1 (22 Nov 2017)
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Protein
Submitted name:

Uncharacterized protein

Gene

FL83_05072

Organism
Caenorhabditis latens
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, TranslocationSAAS annotation, Transport
LigandMetal-bindingSAAS annotation, ZincSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:FL83_05072Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis latensImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1503980 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000216463 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei107 – 127HelicalSequence analysisAdd BLAST21
Transmembranei147 – 168HelicalSequence analysisAdd BLAST22
Transmembranei175 – 194HelicalSequence analysisAdd BLAST20
Transmembranei200 – 223HelicalSequence analysisAdd BLAST24
Transmembranei235 – 256HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane, MitochondrionSAAS annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini25 – 84zf-Tim10_DDPInterPro annotationAdd BLAST60

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni296 – 325DisorderedSequence analysisAdd BLAST30
Regioni1022 – 1042DisorderedSequence analysisAdd BLAST21
Regioni1758 – 1839DisorderedSequence analysisAdd BLAST82

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili501 – 528Sequence analysisAdd BLAST28
Coiled coili541 – 610Sequence analysisAdd BLAST70
Coiled coili628 – 669Sequence analysisAdd BLAST42
Coiled coili707 – 741Sequence analysisAdd BLAST35
Coiled coili743 – 818Sequence analysisAdd BLAST76
Coiled coili822 – 849Sequence analysisAdd BLAST28
Coiled coili871 – 908Sequence analysisAdd BLAST38
Coiled coili926 – 974Sequence analysisAdd BLAST49
Coiled coili1125 – 1145Sequence analysisAdd BLAST21
Coiled coili1178 – 1272Sequence analysisAdd BLAST95
Coiled coili1276 – 1342Sequence analysisAdd BLAST67
Coiled coili1347 – 1367Sequence analysisAdd BLAST21
Coiled coili1375 – 1441Sequence analysisAdd BLAST67
Coiled coili1449 – 1515Sequence analysisAdd BLAST67
Coiled coili1530 – 1614Sequence analysisAdd BLAST85
Coiled coili1639 – 1740Sequence analysisAdd BLAST102

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1779 – 1808PolarSequence analysisAdd BLAST30
Compositional biasi1814 – 1828PolyampholyteSequence analysisAdd BLAST15

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.287.810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004217 Tim10-like
IPR035427 Tim10-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02953 zf-Tim10_DDP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF144122 SSF144122, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

A0A261CDI9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDQLLDVETL KKLSPEQQEQ VISGVKQQAA LANAQNLVTD ISEKCTNKCI
60 70 80 90 100
TAPGSSLASG EKQCLQRCMD RFMESWNLVS QTLQKRLQEE MASSGGMGGG
110 120 130 140 150
FGQGPSFSMT SLINILGLMF SVYFYTWLHP DLKANVRIGL HRFKVDWTIY
160 170 180 190 200
IGSIIWFILG VCFIAPNYTR RTNALAGNIG MAICSVLVVL NHYLLEIKWA
210 220 230 240 250
WSGLLYMANI VFYVLFMGMA MMGQTATYYY DRNRIINVSI PVVSNIFVTG
260 270 280 290 300
MLISVIQDTG FADTVPCISF GIHTCMAILA QVNRIIHSRN QIMDTSESFN
310 320 330 340 350
DENKPQGKKR QQIESPFSAA TPKSRIGKEP KRLFGNAFHN LADSNLEETR
360 370 380 390 400
IETDSRPNSA APEDITLDAT DASTIYRGSE VDPNLEETEL YSAGTSVNST
410 420 430 440 450
NDLSMVDESD ETNADITLAS NFQEKVFLHE TQTTPTAPCV LSPIAMGDDS
460 470 480 490 500
TPTAPTALHL GSEMGLETID THSVESIQSP LGNSKPHIDY SLYEFEILEQ
510 520 530 540 550
KVEHEVTVKE LQEKIETLKE MHRKELQEIN QSRVFEEQLL MKQMDAANKK
560 570 580 590 600
AKSDREAAKE REKSLQQIAD ELKTKLDEPD EEKQQLEKQL AELSSRIEEL
610 620 630 640 650
TQKAVNVDAM QQNSAEHQDR VQEFEHFKLE NSAQLTNARQ EIEELQRKTA
660 670 680 690 700
EMEKKVQEAN EEVERVRQEL CSSTKLEDLK AEHEVVRTML MNEITLLETQ
710 720 730 740 750
LSENSQSNLQ TQEIETLRKK IQELEAEAIQ AVEDKDILHA DFSAKQEAAA
760 770 780 790 800
SEAQEKMVEL NEAKEKVAEL MEEIAKLREE ASNNVRVTEL EQELEENRKL
810 820 830 840 850
MISEMASLEQ QLESARCNSG VNEDLEGKYE TAEARIQELE SALEVNKQNF
860 870 880 890 900
HGIRIELEQK ASMVIELTDS MNALQQVLAE NSQKVSELES SKAKIDELNL
910 920 930 940 950
ALEAAHMQLD EIKFSSEETS TFKEKLVASE ARVHELAASL DSLTEKMDAL
960 970 980 990 1000
LQKNEKSDKE ILCLQTEIEA ARREFDIEEE GSSAKIRHLE LTVQENEAAR
1010 1020 1030 1040 1050
KSLEEVVEEC KKDLQDAKNK LEETQKESVL REETSNEYQN KLKQAEEENQ
1060 1070 1080 1090 1100
ELWANIKALE EEKESTAEKE QSSQVKIQEL EASLDALRQS SNISEALRSE
1110 1120 1130 1140 1150
VDASVAIIQD LQAQLEIAHQ TSDSVNELEK QLETSTATIH ELRSSEESLR
1160 1170 1180 1190 1200
VQLEAATKMI DEFTGLKETV EAQHVAACES LSSELNIVSQ QKEELDQNKQ
1210 1220 1230 1240 1250
ALETRIQELE SSLESLERDL TDQKDEKDRI NAELESTRRN VERREAAILE
1260 1270 1280 1290 1300
LREQHEGKVS ELNSQINESQ QKATESLDLQ SKIVELTEEL ENVRAELTGA
1310 1320 1330 1340 1350
EIINQETIQE LRAEVESSHR MISQQKEQLA ESVAKMEKQE ADFIAQVKLN
1360 1370 1380 1390 1400
QEQIEQLQST IQEFEASNNL SRGVEESTQQ TIQQLTSEVE NSQKTISEQK
1410 1420 1430 1440 1450
EQLNEAVARI EKYETELSIQ SAQHQEQLEK LQSKIQEIEA SNSLTRGTEE
1460 1470 1480 1490 1500
SNQQMIEKLK EEVESYQKTI LDQKVQLEES IARVEKQEAE LTIQAAQYQD
1510 1520 1530 1540 1550
QISQLQSTIQ AFDDSKHSAE VKSLELMSRI DELEASVIVA QKGAEEMKAE
1560 1570 1580 1590 1600
KENLLEQARE QLEQMKQNVE SEKSVLQQDL QQSNEKLEAA EQALSSKENT
1610 1620 1630 1640 1650
VVTLESRIET MSRQFEERLK AADEWKAQAM NIGTMTASMT QMQQQMKEMA
1660 1670 1680 1690 1700
EKLEESKRRV EEVEENAHHD ITIMQDEKNE QSAALEEAKS QIAALDAKLK
1710 1720 1730 1740 1750
KAEKEIERLE KVCDEFDDEE SGYKEQISKL EAEIKQLKGV KSPPKVMGLI
1760 1770 1780 1790 1800
QQARLNVKPL SRESSHMEPP ISEDGFEDAQ DSFQPNSTQA HQKSFNQTAR
1810 1820 1830
QDKTMNVASA TMLHPDDHAH EKSAIETPSK KNRSNCQQQ
Length:1,839
Mass (Da):208,434
Last modified:November 22, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0E4CA678C8F6B930
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
NIPN01000013 Genomic DNA Translation: OZG20579.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NIPN01000013 Genomic DNA Translation: OZG20579.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.10.287.810, 1 hit
InterProiView protein in InterPro
IPR004217 Tim10-like
IPR035427 Tim10-like_dom_sf
PfamiView protein in Pfam
PF02953 zf-Tim10_DDP, 1 hit
SUPFAMiSSF144122 SSF144122, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A261CDI9_9PELO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A261CDI9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: June 5, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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