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Protein

Argininosuccinate lyase

Gene

argH

Organism
Nostoc sp. RF31Y
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.UniRule annotationSAAS annotation

Pathwayi: L-arginine biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes L-arginine from L-ornithine and carbamoyl phosphate.UniRule annotationSAAS annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Argininosuccinate synthase (argG)
  3. Argininosuccinate lyase (argH)
This subpathway is part of the pathway L-arginine biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-arginine from L-ornithine and carbamoyl phosphate, the pathway L-arginine biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processAmino-acid biosynthesis, Arginine biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00068; UER00114

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate lyaseUniRule annotationSAAS annotation (EC:4.3.2.1UniRule annotationSAAS annotation)
Short name:
ASALUniRule annotation
Alternative name(s):
ArginosuccinaseUniRule annotation
Gene namesi
Name:argHUniRule annotation
ORF Names:BV378_38085Imported
OrganismiNostoc sp. RF31YImported
Taxonomic identifieri1932668 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000195154 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 303Lyase_1InterPro annotationAdd BLAST294
Domaini367 – 435ASL_C2InterPro annotationAdd BLAST69

Sequence similaritiesi

Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.UniRule annotationSAAS annotation

Family and domain databases

CDDicd01359 Argininosuccinate_lyase, 1 hit
Gene3Di1.10.275.10, 2 hits
HAMAPiMF_00006 Arg_succ_lyase, 1 hit
InterProiView protein in InterPro
IPR029419 Arg_succ_lyase_C
IPR009049 Argininosuccinate_lyase
IPR024083 Fumarase/histidase_N
IPR020557 Fumarate_lyase_CS
IPR000362 Fumarate_lyase_fam
IPR022761 Fumarate_lyase_N
IPR008948 L-Aspartase-like
PANTHERiPTHR43814 PTHR43814, 1 hit
PfamiView protein in Pfam
PF14698 ASL_C2, 1 hit
PF00206 Lyase_1, 1 hit
PRINTSiPR00149 FUMRATELYASE
SUPFAMiSSF48557 SSF48557, 1 hit
TIGRFAMsiTIGR00838 argH, 1 hit
PROSITEiView protein in PROSITE
PS00163 FUMARATE_LYASES, 1 hit

Sequencei

Sequence statusi: Complete.

A0A252CQG1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEQKTWSQR FESALHPAIA RFNASIDFDI ELIEYDLTGS QAHAKMLAHT
60 70 80 90 100
GIISAQEGEQ LVAGLEQIRQ EYRQGKFQPG IDAEDVHFAV ERRLTEIVGD
110 120 130 140 150
VGKKLHTARS RNDQVGTDTR LYLRDQIQQI QSQLREFQTV LLDIAEKNIE
160 170 180 190 200
TLIPGYTHLQ RAQPLSLAHH LLAYFQMAQR DWERLRDVYQ RVNISPLGCG
210 220 230 240 250
ALAGTTFPID RHYTAQLLEF ENIYANSLDG VSDRDFAIEF LCAASIIMVH
260 270 280 290 300
LSRLSEEVIL WSSEEFRFVT LKDTCATGSS IMPQKKNPDV PELVRGKTGR
310 320 330 340 350
VFGHLQAMLV IMKGLPLAYN KDLQEDKEGL FDSVNTVKAC LEAMTILLRE
360 370 380 390 400
GLEFRPQRLA QAVTEDFSNA TDVADYLAAK GVPFREAYNL VGKVVKTSIT
410 420 430 440 450
AGKLLKDLTL EEWQQIHPTF AADIYQAISP RQVVAARNSY GGTGFEQVRH
460
AILAARTQIA EPKD
Length:464
Mass (Da):52,232
Last modified:November 22, 2017 - v1
Checksum:iCF624B0CCDF77F55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MTAX01000146 Genomic DNA Translation: OUL17584.1

Similar proteinsi

Entry informationi

Entry nameiA0A252CQG1_9NOSO
AccessioniPrimary (citable) accession number: A0A252CQG1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: July 18, 2018
This is version 9 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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