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Protein

Nuclear receptor coactivator

Gene

NCOA3

Organism
Castor canadensis (Beaver)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorUniRule annotation, ReceptorImported
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear receptor coactivatorUniRule annotation
Gene namesi
Name:NCOA3Imported
OrganismiCastor canadensis (Beaver)Imported
Taxonomic identifieri51338 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaCastorimorphaCastoridaeCastor

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 83BHLHInterPro annotationAdd BLAST58
Domaini118 – 181PASInterPro annotationAdd BLAST64

Sequence similaritiesi

Belongs to the SRC/p160 nuclear receptor coactivator family.UniRule annotation

Keywords - Domaini

RepeatSAAS annotation

Family and domain databases

CDDicd00083 HLH, 1 hit
cd00130 PAS, 1 hit
Gene3Di1.10.287.1070, 1 hit
4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR010011 DUF1518
IPR032565 DUF4927
IPR036638 HLH_DNA-bd_sf
IPR028818 NCOA3
IPR009110 Nuc_rcpt_coact
IPR014920 Nuc_rcpt_coact_Ncoa-typ
IPR037077 Nuc_rcpt_coact_Ncoa_int_sf
IPR017426 Nuclear_rcpt_coactivator
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013767 PAS_fold
IPR014935 SRC/p160_LXXLL
PANTHERiPTHR10684 PTHR10684, 1 hit
PTHR10684:SF3 PTHR10684:SF3, 1 hit
PfamiView protein in Pfam
PF07469 DUF1518, 1 hit
PF16279 DUF4927, 1 hit
PF08815 Nuc_rec_co-act, 1 hit
PF00989 PAS, 1 hit
PF08832 SRC-1, 1 hit
PIRSFiPIRSF038181 Nuclear_receptor_coactivator, 1 hit
SMARTiView protein in SMART
SM01151 DUF1518, 1 hit
SM00353 HLH, 1 hit
SM00091 PAS, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
SSF55785 SSF55785, 2 hits
SSF69125 SSF69125, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS50112 PAS, 1 hit

Sequencei

Sequence statusi: Complete.

A0A250YM83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGLGENSLD PLSTDSRKRK LPCDTPGQGL TCSGEKWRRE QESKYIEELA
60 70 80 90 100
ELISANLSDI DNFNVKPDKC AILKETVRQI RQIKEQGKAI SNDDDVQKAD
110 120 130 140 150
VSSTGQGVID KDSLGPLLLQ ALDGFLFVVN RDGNIVFVSE NVAQYLQYKQ
160 170 180 190 200
EELVNTSVYT ILHEEDRKDF LKNLPKSTVN GVSWTNETQR QKSHTFNCRM
210 220 230 240 250
LMKTTRDILE DMNTSPEIRQ RYETMQCFAL SQPRAMMEEG EDLQSCMICV
260 270 280 290 300
ARRITTGERA FPSNPESFIT RHDLSGKVVN IDTNSLRSSM RPGFEDIIRR
310 320 330 340 350
CIQRFFSLND GQSWSQKRHY QEAYIHGHAE TPVYRFSLAD GTIVTAQTKS
360 370 380 390 400
KLFRNPVTND RHGFVSTHFL QREQNGYRPN SNPVGQGIRP PAGGCSSSIG
410 420 430 440 450
GMSMSPSQSL QMLTSRSYGL ADPSTTGQMS GARYGASSNI ASLTTGPGIQ
460 470 480 490 500
SPSSYQNNNY GLNMSSPPHG SPGLGSNQQN IMISPRNRGS PKMTSHQFSP
510 520 530 540 550
GAGVHSPMGT SGSTGSHSFS SSSLSALQAI SEGVGTSLLS TLSSPGPKLD
560 570 580 590 600
NSPSMNITQP GKVSSQESKS PLGLYCDQNP VESSGCQSNS RDHLSDKENK
610 620 630 640 650
ESSGEGSENQ RGPLESKGHK KLLQLLTCSS DDRGHSSLTN SPLDSSCKDS
660 670 680 690 700
SVSVTSPSGV SSSTSGGVSS TSNVHGSLLQ EKHRILHKLL QNGNSPAEVA
710 720 730 740 750
KITAEATGKD TSSTASCGEG SVKQEQLSPK KKENNALLRY LLDRDDPSDA
760 770 780 790 800
LSKELQPQVE GIDGKISQCS SATIPSSSQE KDSKVKTETN EEGSGDLDNL
810 820 830 840 850
DAILGDLTGS DFYSNSVSTN GSHLGTKQQI FQGTNSLGLR SPQPVQSIRP
860 870 880 890 900
PYNRAVSLDS PVSVGSNPPV KTVSAFPMLP KQSMLGGNPR MLDSQESYGC
910 920 930 940 950
NMGGPNRNVT VNQTPSSGDW GLPNSKVSKM EPMSSNSMGR PGGDYSASLP
960 970 980 990 1000
RPAVGGSMPT LPLRSNSIPG TRPMLQQQQI LQMRPAEIPM GIGVSLYGQP
1010 1020 1030 1040 1050
APSAQPGSWP DGMLSMEQGP HGTQNRPLLR NSLDDLLGPP SNPEGQSDER
1060 1070 1080 1090 1100
ALLDQLHTLL SNTDATGLEE IDRALGIPEL VNQGQALEPK QDAFQGQEAA
1110 1120 1130 1140 1150
VMMDQKAVLY GQTYPAQGPP MQGGFNLQGQ SPSFNSMMNQ MNQQGSFPLQ
1160 1170 1180 1190 1200
GMHPRASIMR PRTNTPKQLR MQLQQRLQGQ QFLNQSRQAL EMKMENPTAG
1210 1220 1230 1240 1250
GAAVVRPVMQ PQMSSQGFLN AQMVAQRSRE LLSHHFRQQR VAMMMQQQQQ
1260 1270 1280 1290 1300
QQQQQQQTQA FSPPPNVTAS PSMDGVLAGP AMPQAPPQQF SYPPSYGMGQ
1310 1320 1330 1340 1350
QPDPAFGRVS SPPNAMMSSR MGPTQNPMMQ HPQTAPMYQS SEMKGWPSGN
1360 1370 1380 1390 1400
LARNSTFPQQ QFAHQGSPAA YSMVHMNGSS SHLGQMSMNS MPMSGMPMGP

DQKYC
Length:1,405
Mass (Da):152,234
Last modified:November 22, 2017 - v1
Checksum:iE090AE632C395374
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GFFW01000056 Transcribed RNA Translation: JAV44732.1
RefSeqiXP_020036043.1, XM_020180454.1

Genome annotation databases

GeneIDi109697081

Similar proteinsi

Entry informationi

Entry nameiA0A250YM83_CASCN
AccessioniPrimary (citable) accession number: A0A250YM83
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: July 18, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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