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Protein

Non-specific serine/threonine protein kinase

Gene

PAK4

Organism
Castor canadensis (Beaver)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesi
Name:PAK4Imported
OrganismiCastor canadensis (Beaver)Imported
Taxonomic identifieri51338 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaCastorimorphaCastoridaeCastor

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 24CRIBInterPro annotationAdd BLAST14
Domaini320 – 571Protein kinaseInterPro annotationAdd BLAST252

Phylogenomic databases

KOiK05734

Family and domain databases

CDDicd01093 CRIB_PAK_like, 1 hit
Gene3Di3.90.810.10, 1 hit
InterProiView protein in InterPro
IPR000095 CRIB_dom
IPR036936 CRIB_dom_sf
IPR011009 Kinase-like_dom_sf
IPR033923 PAK_BD
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00786 PBD, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00285 PBD, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50108 CRIB, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Complete.

A0A250Y3B7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFGKRKKRVE ISAPSNFEHR VHTGFDQHEQ KFTGLPRQWQ SLIEESARRP
60 70 80 90 100
KPLVDPACIT SIQPGAPKTI VRGSKGAKDG ALTLLLDEFE NMSVTRSNSL
110 120 130 140 150
RRDSPPPPGR PRQENGMPEE RAPTARGSPE KAGGRGRATS RNEAGGGSGD
160 170 180 190 200
RRRVGPEKRP KSSKEGPTGS QESSRDKRPL SGPDVGTPQP AGLASGAKLA
210 220 230 240 250
AGRPFNTYPR ADTDHPPRGA QGETHDMAPN GPSAGGLAAP QSSRPPARAR
260 270 280 290 300
GTPSPGVLGP HASEPQLAPP ARALASPAVP PATGPPGPRS PQREPQRVSH
310 320 330 340 350
EQFRAALQLV VDPGDPRSYL DNFIKIGEGS TGIVCIATVR SSGKLVAVKK
360 370 380 390 400
MDLRKQQRRE LLFNEVVIMR DYRHENVVEM YNSYLVGDEL WVVMEFLEGG
410 420 430 440 450
ALTDIVTHTR MNEEQIAAVC LAVLQALSVL HAQGVIHRDI KSDSILLTHD
460 470 480 490 500
GRVKLSDFGF CAQVSKEVPR RKSLVGTPYW MAPELISRLP YGPEVDIWSL
510 520 530 540 550
GVMVIEMVDG EPPYFNEPPL KAMKMIRDNL PPRLKNLHKV SPSLKGFLDR
560 570 580 590
LLVRDPAQRA TAAELLKHPF LAKAGPPASI VPLMRQHRNR
Length:590
Mass (Da):64,315
Last modified:November 22, 2017 - v1
Checksum:i2C986D9C8AE04DC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GFFV01001901 Transcribed RNA Translation: JAV38044.1
RefSeqiXP_020040843.1, XM_020185254.1

Genome annotation databases

GeneIDi109700193
KEGGiccan:109700193

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GFFV01001901 Transcribed RNA Translation: JAV38044.1
RefSeqiXP_020040843.1, XM_020185254.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi109700193
KEGGiccan:109700193

Organism-specific databases

CTDi10298

Phylogenomic databases

KOiK05734

Family and domain databases

CDDicd01093 CRIB_PAK_like, 1 hit
Gene3Di3.90.810.10, 1 hit
InterProiView protein in InterPro
IPR000095 CRIB_dom
IPR036936 CRIB_dom_sf
IPR011009 Kinase-like_dom_sf
IPR033923 PAK_BD
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00786 PBD, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00285 PBD, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50108 CRIB, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A250Y3B7_CASCN
AccessioniPrimary (citable) accession number: A0A250Y3B7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2017
Last sequence update: November 22, 2017
Last modified: November 7, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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