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Protein
Submitted name:

Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase

Gene

CA163_21880

Organism
Vibrio parahaemolyticus
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.SAAS annotation

Pathwayi: L-tryptophan biosynthesis

This protein is involved in step 4 of the subpathway that synthesizes L-tryptophan from chorismate.SAAS annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Anthranilate synthase component 1 (YA91_14505), Anthranilate synthase component 1 (C1S91_13755), Anthranilate synthase component 1 (BA740_05030), Anthranilate synthase component 1 (ACS91_03520), Anthranilate synthase component 1 (AAY51_06950), Anthranilate synthase component 1 (WR32_18285), Anthranilate synthase component 1 (CNR26_20435), Anthranilate synthase component 1 (ACX03_18600), Anthranilate synthase component 1 (BBM75_23365)
  2. Anthranilate phosphoribosyltransferase (trpD), Anthranilate phosphoribosyltransferase (trpD), Anthranilate phosphoribosyltransferase (trpD), Anthranilate phosphoribosyltransferase (trpD), Anthranilate phosphoribosyltransferase (trpD), Anthranilate phosphoribosyltransferase (trpD), Anthranilate phosphoribosyltransferase (trpD), Anthranilate phosphoribosyltransferase (trpD)
  3. Multifunctional fusion protein (trpC), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpC), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpC), Multifunctional fusion protein (trpC), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpF)
  4. Multifunctional fusion protein (trpC), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpC), Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase (CA163_21880), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpC), Multifunctional fusion protein (trpC), Multifunctional fusion protein (trpF), Multifunctional fusion protein (trpF)
  5. Tryptophan synthase beta chain (trpB), Tryptophan synthase alpha chain (trpA), Tryptophan synthase beta chain (trpB), Tryptophan synthase beta chain (trpB), Tryptophan synthase alpha chain (trpA), Tryptophan synthase beta chain (trpB), Tryptophan synthase alpha chain (trpA), Tryptophan synthase alpha chain (trpA), Tryptophan synthase beta chain (trpB), Tryptophan synthase beta chain (trpB), Tryptophan synthase beta chain (trpB), Tryptophan synthase alpha chain (trpA), Tryptophan synthase beta chain (trpB), Tryptophan synthase beta chain (trpB), Tryptophan synthase alpha chain (trpA), Tryptophan synthase alpha chain (trpA)
This subpathway is part of the pathway L-tryptophan biosynthesis, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-tryptophan from chorismate, the pathway L-tryptophan biosynthesis and in Amino-acid biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseImported, LyaseSAAS annotationImported
Biological processAmino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesisSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00035; UER00043

Names & Taxonomyi

Protein namesi
Submitted name:
Bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomeraseImported (EC:4.1.1.48Imported, EC:5.3.1.24Imported)
Gene namesi
ORF Names:CA163_21880Imported
OrganismiVibrio parahaemolyticusImported
Taxonomic identifieri670 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000214596 Componenti: Unassembled WGS sequence

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 124IGPSInterPro annotationAdd BLAST124

Family and domain databases

CDDicd00331 IGPS, 1 hit
Gene3Di3.20.20.70, 1 hit
InterProiView protein in InterPro
IPR013785 Aldolase_TIM
IPR013798 Indole-3-glycerol_P_synth
IPR011060 RibuloseP-bd_barrel
PfamiView protein in Pfam
PF00218 IGPS, 1 hit
SUPFAMiSSF51366 SSF51366, 1 hit

Sequencei

Sequence statusi: Fragment.

A0A227J6H7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
QPVLCKDFMV DTYQVYLARH YGADAVLLML SVLNDEEYKA LEEAAHSLNM
60 70 80 90 100
GILTEVSNEE ELHRAVQLGA RVIGINNRNL RDLTTDLNRT KALAPTIRKL
110 120
APNATVISES GIYTHQQVRD LAEYADG
Length:127
Mass (Da):14,184
Last modified:October 25, 2017 - v1
Checksum:i53103C8D196E2928
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei127Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
NIXT01001940 Genomic DNA Translation: OXE30716.1

Similar proteinsi

Entry informationi

Entry nameiA0A227J6H7_VIBPH
AccessioniPrimary (citable) accession number: A0A227J6H7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2017
Last sequence update: October 25, 2017
Last modified: December 20, 2017
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

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