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UniProtKB - A0A224XDX0 (A0A224XDX0_9HEMI)

Entry version 7 (07 Oct 2020)
Sequence version 1 (25 Oct 2017)
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Protein
Submitted name:

Putative conserved plasma membrane protein

Gene
N/A
Organism
Panstrongylus lignarius
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processrRNA processingARBA annotation, tRNA processingARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative conserved plasma membrane proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPanstrongylus lignariusImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri156445 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Paraneoptera › Hemiptera › Heteroptera › Panheteroptera › Cimicomorpha › Reduviidae › Triatominae › Panstrongylus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei289 – 308HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane, NucleusARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini107 – 201DUF1726InterPro annotationAdd BLAST95
Domaini279 – 475Helicase_RecDInterPro annotationAdd BLAST197
Domaini515 – 738N-acetyltransferaseInterPro annotationAdd BLAST224
Domaini746 – 962tRNA_bind_2InterPro annotationAdd BLAST217

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili917 – 944Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

HAMAP database of protein families

More...HAMAPi		MF_03211, RNA_acetyltr_Nat10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000182, GNAT_dom
IPR007807, Helicase_dom
IPR033688, NAT10
IPR032672, TmcA/NAT10/Kre33
IPR013562, TmcA_N
IPR027992, tRNA_bind_dom

The PANTHER Classification System

More...PANTHERi		PTHR10925, PTHR10925, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08351, DUF1726, 1 hit
PF13718, GNAT_acetyltr_2, 1 hit
PF05127, Helicase_RecD, 1 hit
PF13725, tRNA_bind_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

A0A224XDX0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRTKIDNRI RLLIENGIKC SHRTMFVVVG DKGRDQVMIL HHILSKAVVK 
        60         70         80         90        100
ARPSVLWCYK KELGFSSNKM KRMKHVQRKI KIGKININED DPFELFIAST 
       110        120        130        140        150
NIRYCYYSET QKILGQTFGV CVLQDFEAIT PNLLARTIET VEGGGLVILL 
       160        170        180        190        200
LRTLTSLKQL YDMTMDVHER YRTEAHTDVV GRFNERFLLS LSSCKRCLVV 
       210        220        230        240        250
DDQLKILPIS SHVFDIQSMP DNAIVNQSDE DLKKLQDNLR DTQPVSSLIN 
       260        270        280        290        300
CCKTLDQAKA VLKFIDAISE KSLRYTVSLT AARGRGKSAA LGIAVAGAIA 
       310        320        330        340        350
FGYSNIFVTS PSPDNLKTFF EFVFKGFDVL GYQEHLDYGL VQSTNVEHNK 
       360        370        380        390        400
ALIRVNVFKT NRQTIQYISP LDSNKLSHAE LLVIDEAAAI PLPYVKNMFG 
       410        420        430        440        450
PYLIFLSSTI NGYEGTGRSL SLKLLQELRK QSTGSNDASN TPSKRTLYEI 
       460        470        480        490        500
TLEESIRYKP GDAVEQWLTE LLCLDATNSE RLWSGVPSPS ECDLYYINRD 
       510        520        530        540        550
TLFCFHKASE AFLHKIMALY VSSHYKNSPN DLQLMSDAPA HHLFCLLGPV 
       560        570        580        590        600
DPKKTVLPEV LCVIQVCLEG QISKRSVNVS LSHGNKPTGD LIPWTIAHQF 
       610        620        630        640        650
QDDEFPTLSG LRIVRIATHP DYQSMGYGAR ALSLLNDYYS LKIPVLDDLK 
       660        670        680        690        700
TTTGQQRNDR NGEEDLYNEI IEPRSSLPPL LMKLGERAPE KLDYLGVSYG 
       710        720        730        740        750
LTLPLLRFWK KADFVPVYLR QTSNDLTGEH SCIMLKSLSE NENASWLNQY 
       760        770        780        790        800
WLDFRRRFIS LLSYQFRVFT TSLALGVIFN KQEKDMSSCL KKEELDCHIT 
       810        820        830        840        850
KYDLKRLELY CNNVADYHLI MDLMPSLAKL FFLDQLGHIK CTAIQLALLV 
       860        870        880        890        900
GVGLQHKTVD EVAKELDLPL SQLLGLQIRL IKKIYHVIMN IVEDSVEQTL 
       910        920        930        940        950
GLNQNSNIKL NADNTPLQDL NEELEKADKK IRKKQKREKN MLKEEYGSEF 
       960        970        980        990       1000
AIKGSEDQWS EALSSGNSNI LSIKSGKMFV SESPSEHQDY TMIXXREKNM 
      1010 
LKEEYGSEFA I
Length:1,011
Mass (Da):114,844
Last modified:October 25, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i175FBB14E2B82788
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1011Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
GFTR01008438 Transcribed RNA Translation: JAW07988.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GFTR01008438 Transcribed RNA Translation: JAW07988.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

Family and domain databases

HAMAPiMF_03211, RNA_acetyltr_Nat10, 1 hit
InterProiView protein in InterPro
IPR000182, GNAT_dom
IPR007807, Helicase_dom
IPR033688, NAT10
IPR032672, TmcA/NAT10/Kre33
IPR013562, TmcA_N
IPR027992, tRNA_bind_dom
PANTHERiPTHR10925, PTHR10925, 1 hit
PfamiView protein in Pfam
PF08351, DUF1726, 1 hit
PF13718, GNAT_acetyltr_2, 1 hit
PF05127, Helicase_RecD, 1 hit
PF13725, tRNA_bind_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A224XDX0_9HEMI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A224XDX0
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2017
Last sequence update: October 25, 2017
Last modified: October 7, 2020
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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