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Protein

Probable malate:quinone oxidoreductase

Gene

mqo1

Organism
Actinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotationSAAS annotation

Cofactori

FADUniRule annotationSAAS annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo), Probable malate:quinone oxidoreductase (mqo1)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationSAAS annotationImported
Biological processTricarboxylic acid cycleUniRule annotationSAAS annotation
LigandFADUniRule annotationSAAS annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayi
UPA00223;UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqo1Imported
Synonyms:mqoUniRule annotation
ORF Names:CHY23_00510Imported
OrganismiActinobacillus pleuropneumoniae (Haemophilus pleuropneumoniae)Imported
Taxonomic identifieri715 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeActinobacillus

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotationSAAS annotation

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

A0A223MCN3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQDSSSALES YSDVTLIGAG IMSGTLGAFL TELAPEKSLA IFEKLSAVGL
60 70 80 90 100
ESSNEWNNAG TGHSALCELN YTEQKADGEV SVERAVKICE DFQLSLQLWS
110 120 130 140 150
YLVETGRIQA PREFIHRIPH ISFVQGEQNA QFLQKRYQSL AQSHLFEGMQ
160 170 180 190 200
FSRDHQQLAQ WMPLMMQNRD SNETLAASYI QYGTDVNFGE LTRKLFDYLV
210 220 230 240 250
KQKAELNLNH RVKNIQRLAN GEWKLTVVDQ QGQKRVHRSK FVFIGGGGGA
260 270 280 290 300
LPLLQKSGIT DGKNVGGFPV SGLFMVCNNP EVIAKHNAKV YGKAKLGAPP
310 320 330 340 350
MSVPHLDTRF IEGKQSLLFG PFAGFTLKFL KQGSVLDLPT SVTPTNFCSV
360 370 380 390 400
TKAGIKNLPL AHYLMKQAML TKAQRMADLR EFVPDAKDED WDVVVAGQRV
410 420 430 440 450
QVIKGGEMRF GTEVIRAEDG SLAALLGASP GASTSVKAML DVLVSCFAAE
460 470 480 490
LPQWQAKLTQ MLPSYGKALR SEPQLYAQIK QRVDQVLALA N
Length:491
Mass (Da):54,103
Last modified:October 25, 2017 - v1
Checksum:i492742F577350787
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP022715 Genomic DNA Translation: ASU15303.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP022715 Genomic DNA Translation: ASU15303.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayi
UPA00223;UER01008

Family and domain databases

Gene3Di3.50.50.60, 1 hit
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 1 hit
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A223MCN3_ACTPL
AccessioniPrimary (citable) accession number: A0A223MCN3
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2017
Last sequence update: October 25, 2017
Last modified: November 7, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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