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Entry version 13 (11 Dec 2019)
Sequence version 1 (25 Oct 2017)
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Protein
Submitted name:

DNA-binding SARP family transcriptional activator

Gene

DES30_103473

Organism
Prauserella marina
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingImported
Biological processTranscription, Transcription regulationSAAS annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
DNA-binding SARP family transcriptional activatorImported
Submitted name:
DNA-binding transcriptional activator of the SARP familyImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:DES30_103473Imported, SAMN05421630_109258Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPrauserella marinaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri530584 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaePrauserella
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000199494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000246674 Componenti: Unassembled WGS sequence

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini762 – 914TPR_REGIONInterPro annotationAdd BLAST153

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni625 – 649DisorderedSequence analysisAdd BLAST25

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.10.10, 1 hit
1.25.40.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005158 BTAD
IPR002182 NB-ARC
IPR001867 OmpR/PhoB-type_DNA-bd
IPR027417 P-loop_NTPase
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR041617 TPR_MalT
IPR019734 TPR_repeat
IPR036388 WH-like_DNA-bd_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03704 BTAD, 1 hit
PF00931 NB-ARC, 1 hit
PF17874 TPR_MalT, 1 hit
PF00486 Trans_reg_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01043 BTAD, 1 hit
SM00028 TPR, 4 hits
SM00862 Trans_reg_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF46894 SSF46894, 1 hit
SSF48452 SSF48452, 3 hits
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50293 TPR_REGION, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A222VS09-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGERTDDARA SAESLAFGVL GPFTVRRAGK RVVLPSGQTP QLLAVLVLNQ
60 70 80 90 100
GSLVSHELLS EVLWDEDPPA SARKLIQVRL SQLRRLLGEG AELVGGRQGY
110 120 130 140 150
RLEIPSAEVD LHEFRRLVAD AELVPPEAAE PLLHNALRLW RGVALDELSG
160 170 180 190 200
TVRGARIVAG LEEERLAAVS AHAEAALATG RCPGLVTDLA SIVAEYPLRE
210 220 230 240 250
RLRAHLMRAL HRAGRQAEAL AAFEEGRVLL AEELGLDPGK ELREAHAEIL
260 270 280 290 300
EGDSALAHPE VARPATAGAV PSVPRQLPGA PAHFVGRQAE SAALISAATG
310 320 330 340 350
AGDGPALVAV HGQGGQGKSA LVLHVAQQLA DSFPDGQLYV DLLGSTPGAS
360 370 380 390 400
PLAAEDVLRR FLRSFGVPAH AVPQDPTESS AMFRSAIAGK KVLVVLDNAV
410 420 430 440 450
DSAQVVPLLP AGPGTAVLVT SRRILATLDS LSVALEPLAT ADAVALFASH
460 470 480 490 500
LDRALTQRER GAAKRVAEVC GHLPLAVRIA AARLRGRPDW TVTHLLDRLA
510 520 530 540 550
DQRRRLDELD FDNLAVRSSM ELSYRDLDDG AARAFRLLGL LPLPYVSLPV
560 570 580 590 600
AAALLGHEPD TADTLLEPLV SARLIEVAAP GRYRLHDLVR LFALERAERH
610 620 630 640 650
ESKAERDTAV SRVLDHYQVR LNEAHTRLRP HNRSAEDGEA PPDHDDSPGI
660 670 680 690 700
ADYVRWISDE IDNLVAAARM AAGVAELAPR ALSIAHQLRL YLWAQEMRAD
710 720 730 740 750
AVEIAHLAGT AAERVGTDEA LDLALDVQAL INQHLGRLGE AHALYTRLLD
760 770 780 790 800
VRRRLGDISG QGRTLGNLGI LLRHMGRLDE ALHRLGEAGE LLDEHGPAEA
810 820 830 840 850
KPLVLACLAD VHLQADRPEE GLRHAERSLA LCAETDPTCA VYALVSIGQA
860 870 880 890 900
HSQLGDLPSA LTALSESITL CRTLHLPHDE WEALLCRSEV HVRAGEPDAA
910 920 930 940 950
IADAERVLTL LSNHGDYYAQ GAAHRQFARA FQLKGDELVA VEHASYAESL
960 970
FASPGVRRNP LLERLLARER ADTGESLV
Length:978
Mass (Da):105,119
Last modified:October 25, 2017 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB3E988DD212A0A80
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
QGTN01000003 Genomic DNA Translation: PWV80382.1
FMZE01000009 Genomic DNA Translation: SDD53116.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pmad:BAY61_18960

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
QGTN01000003 Genomic DNA Translation: PWV80382.1
FMZE01000009 Genomic DNA Translation: SDD53116.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

KEGGipmad:BAY61_18960

Family and domain databases

Gene3Di1.10.10.10, 1 hit
1.25.40.10, 3 hits
InterProiView protein in InterPro
IPR005158 BTAD
IPR002182 NB-ARC
IPR001867 OmpR/PhoB-type_DNA-bd
IPR027417 P-loop_NTPase
IPR016032 Sig_transdc_resp-reg_C-effctor
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR041617 TPR_MalT
IPR019734 TPR_repeat
IPR036388 WH-like_DNA-bd_sf
PfamiView protein in Pfam
PF03704 BTAD, 1 hit
PF00931 NB-ARC, 1 hit
PF17874 TPR_MalT, 1 hit
PF00486 Trans_reg_C, 1 hit
SMARTiView protein in SMART
SM01043 BTAD, 1 hit
SM00028 TPR, 4 hits
SM00862 Trans_reg_C, 1 hit
SUPFAMiSSF46894 SSF46894, 1 hit
SSF48452 SSF48452, 3 hits
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS50293 TPR_REGION, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A222VS09_9PSEU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A222VS09
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2017
Last sequence update: October 25, 2017
Last modified: December 11, 2019
This is version 13 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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